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Prediction of the in vivo OATP1B1-mediated drug-drug interaction potential of an investigational drug against a range of statins.
Sharma P, Butters CJ, Smith V, Elsby R, Surry D. Sharma P, et al. Among authors: surry d. Eur J Pharm Sci. 2012 Aug 30;47(1):244-55. doi: 10.1016/j.ejps.2012.04.003. Epub 2012 Apr 19. Eur J Pharm Sci. 2012. PMID: 22538052
Effects of Fostamatinib on the Pharmacokinetics of Oral Contraceptive, Warfarin, and the Statins Rosuvastatin and Simvastatin: Results From Phase I Clinical Studies.
Martin P, Gillen M, Ritter J, Mathews D, Brealey C, Surry D, Oliver S, Holmes V, Severin P, Elsby R. Martin P, et al. Among authors: surry d. Drugs R D. 2016 Mar;16(1):93-107. doi: 10.1007/s40268-015-0120-x. Drugs R D. 2016. PMID: 26748647 Free PMC article. Clinical Trial.
Solitary Inhibition of the Breast Cancer Resistance Protein Efflux Transporter Results in a Clinically Significant Drug-Drug Interaction with Rosuvastatin by Causing up to a 2-Fold Increase in Statin Exposure.
Elsby R, Martin P, Surry D, Sharma P, Fenner K. Elsby R, et al. Among authors: surry d. Drug Metab Dispos. 2016 Mar;44(3):398-408. doi: 10.1124/dmd.115.066795. Epub 2015 Dec 23. Drug Metab Dispos. 2016. PMID: 26700956
Quantification of proteins by flow cytometry: Quantification of human hepatic transporter P-gp and OATP1B1 using flow cytometry and mass spectrometry.
Hogg K, Thomas J, Ashford D, Cartwright J, Coldwell R, Weston DJ, Pillmoor J, Surry D, O'Toole P. Hogg K, et al. Among authors: surry d. Methods. 2015 Jul 1;82:38-46. doi: 10.1016/j.ymeth.2015.03.030. Epub 2015 Apr 24. Methods. 2015. PMID: 25916617
In vitro risk assessment of AZD9056 perpetrating a transporter-mediated drug-drug interaction with methotrexate.
Elsby R, Fox L, Stresser D, Layton M, Butters C, Sharma P, Smith V, Surry D. Elsby R, et al. Among authors: surry d. Eur J Pharm Sci. 2011 May 18;43(1-2):41-9. doi: 10.1016/j.ejps.2011.03.006. Epub 2011 Apr 1. Eur J Pharm Sci. 2011. PMID: 21440623
The utility of in vitro data in making accurate predictions of human P-glycoprotein-mediated drug-drug interactions: a case study for AZD5672.
Elsby R, Gillen M, Butters C, Imisson G, Sharma P, Smith V, Surry DD. Elsby R, et al. Among authors: surry dd. Drug Metab Dispos. 2011 Feb;39(2):275-82. doi: 10.1124/dmd.110.035881. Epub 2010 Nov 12. Drug Metab Dispos. 2011. PMID: 21075975 Clinical Trial.
Validation of membrane vesicle-based breast cancer resistance protein and multidrug resistance protein 2 assays to assess drug transport and the potential for drug-drug interaction to support regulatory submissions.
Elsby R, Smith V, Fox L, Stresser D, Butters C, Sharma P, Surry DD. Elsby R, et al. Among authors: surry dd. Xenobiotica. 2011 Sep;41(9):764-83. doi: 10.3109/00498254.2011.578761. Epub 2011 May 25. Xenobiotica. 2011. PMID: 21612343
Validation of cell-based OATP1B1 assays to assess drug transport and the potential for drug-drug interaction to support regulatory submissions.
Sharma P, Holmes VE, Elsby R, Lambert C, Surry D. Sharma P, et al. Among authors: surry d. Xenobiotica. 2010 Jan;40(1):24-37. doi: 10.3109/00498250903351013. Xenobiotica. 2010. PMID: 19919292
Validation and application of Caco-2 assays for the in vitro evaluation of development candidate drugs as substrates or inhibitors of P-glycoprotein to support regulatory submissions.
Elsby R, Surry DD, Smith VN, Gray AJ. Elsby R, et al. Among authors: surry dd. Xenobiotica. 2008 Jul;38(7-8):1140-64. doi: 10.1080/00498250802050880. Xenobiotica. 2008. PMID: 18668443
Effects of Fostamatinib on the Pharmacokinetics of the CYP2C8 Substrate Pioglitazone: Results From In Vitro and Phase 1 Clinical Studies.
Martin P, Gillen M, Millson D, Oliver S, Brealey C, Surry D, Sweeny D, Lau D, Leese P. Martin P, et al. Among authors: surry d. Clin Pharmacol Drug Dev. 2016 May;5(3):170-9. doi: 10.1002/cpdd.243. Epub 2016 Mar 23. Clin Pharmacol Drug Dev. 2016. PMID: 27163495 Clinical Trial.
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