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Year Number of Results
1987 1
1990 1
1994 1
1995 2
1996 3
1997 1
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2000 1
2003 1
2007 1
2012 1
2013 2
2014 1
2016 2
2018 1
2019 1
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Susceptibility to AIDS progression appears early in HIV infection.
Schechter MT, Craib KJ, Le TN, Montaner JS, Douglas B, Sestak P, Willoughby B, O'Shaughnessy MV. Schechter MT, et al. AIDS. 1990 Mar;4(3):185-90. doi: 10.1097/00002030-199003000-00002. AIDS. 1990. PMID: 2112396
To investigate whether predictors of AIDS progression are operative very early in the natural history of HIV infection, we conducted a nested case-control study within a cohort of 119 subjects who seroconverted while under observation in a prosp …
To investigate whether predictors of AIDS progression are operative very early in the natural history of HIV
Computational study to determine when to initiate and alternate therapy in HIV infection.
Haering M, Hördt A, Meyer-Hermann M, Hernandez-Vargas EA. Haering M, et al. Biomed Res Int. 2014;2014:472869. doi: 10.1155/2014/472869. Epub 2014 May 11. Biomed Res Int. 2014. PMID: 24900966 Free PMC article.
HIV is a widespread viral infection without cure. Drug treatment has transformed HIV disease into a treatable long-term infection. ...We contribute to this discussion with predictions derived from a mathematical model of HIV dynamics. Our
HIV is a widespread viral infection without cure. Drug treatment has transformed HIV disease into a treatable lo
Impact of cellular restriction gene (TRIM5α, BST-2) polymorphisms on the acquisition of HIV-1 and disease progression.
Singh H, Samani D, Ghate MV, Gangakhedkar RR. Singh H, et al. J Gene Med. 2018 Feb;20(2-3):e3004. doi: 10.1002/jgm.3004. Epub 2018 Jan 25. J Gene Med. 2018. PMID: 29282802
BACKGROUND: TRIM5α and BST-2 are cellular restriction factors affecting the HIV-1 infection and its progression. Genetic variability in these genes alters the expression pattern. ...TRIM5α rs7127617 CC and BST-2 Δ19/i19 genotypes in alcohol-using HIV p …
BACKGROUND: TRIM5α and BST-2 are cellular restriction factors affecting the HIV-1 infection and its progression. Geneti …
Reverse geroscience: how does exposure to early diseases accelerate the age-related decline in health?
Kohanski RA, Deeks SG, Gravekamp C, Halter JB, High K, Hurria A, Fuldner R, Green P, Huebner R, Macchiarini F, Sierra F. Kohanski RA, et al. Ann N Y Acad Sci. 2016 Dec;1386(1):30-44. doi: 10.1111/nyas.13297. Epub 2016 Dec 1. Ann N Y Acad Sci. 2016. PMID: 27907230 Free article. Review.
While, previously, the focus was on the role of aging in susceptibility to disease and disability, the other side of this relationship, which is the contribution of disease to aging, has been less explored at the molecular/cellular level. ...A recent summit c …
While, previously, the focus was on the role of aging in susceptibility to disease and disability, the other side of this rela …
Immunodeficiency.
Justiz Vaillant AA, Qurie A. Justiz Vaillant AA, et al. 2019 Nov 22. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2020 Jan–. StatPearls. 2020 Jan–. PMID: 29763203 Free Books & Documents. Review.
Acquired Immune Deficiency Syndrome (AIDS): Caused by human immunodeficiency virus (HIV), which is a retrovirus transmitted sexually, perinatally or blood products. ...Infected cells may be killed by HIV-1 specific CD8+ T cells. In HIV
Acquired Immune Deficiency Syndrome (AIDS): Caused by human immunodeficiency virus (HIV), which is a retr
Immune and hematopoietic parameters in HIV-1-infected chimpanzees during clinical progression toward AIDS.
Villinger F, Brar SS, Brice GT, Chikkala NF, Novembre FJ, Mayne AE, Bucur S, Hillyer CD, Ansari AA. Villinger F, et al. J Med Primatol. 1997 Feb-Apr;26(1-2):11-8. doi: 10.1111/j.1600-0684.1997.tb00314.x. J Med Primatol. 1997. PMID: 9271184
Until recently, chimpanzees were considered susceptible to human immunodeficiency virus type 1 (HIV-1) infection, but refractory to disease induction based on the asymptomatic status of all experimentally infected chimpanzees after over 10 years …
Until recently, chimpanzees were considered susceptible to human immunodeficiency virus type 1 (HIV-1) infection
Infection of gamma/delta T lymphocytes by human herpesvirus 6: transcriptional induction of CD4 and susceptibility to HIV infection.
Lusso P, Garzino-Demo A, Crowley RW, Malnati MS. Lusso P, et al. J Exp Med. 1995 Apr 1;181(4):1303-10. doi: 10.1084/jem.181.4.1303. J Exp Med. 1995. PMID: 7699322 Free PMC article.
Progression of the infection was associated with the appearance of typical cytomorphological changes and, eventually, massive cell death. ...Whereas purified CD4- gamma/delta T cell populations were per se refractory to HIV infection, they becam
Progression of the infection was associated with the appearance of typical cytomorphological changes and, eventually, m
CD4(+) T-cell depletion in HIV infection: mechanisms of immunological failure.
Okoye AA, Picker LJ. Okoye AA, et al. Immunol Rev. 2013 Jul;254(1):54-64. doi: 10.1111/imr.12066. Immunol Rev. 2013. PMID: 23772614 Free PMC article. Review.
The hallmark of acquired immunodeficiency syndrome (AIDS) pathogenesis is a progressive depletion of CD4(+) T-cell populations in close association with progressive impairment of cellular immunity and increasing susceptibility to o …
The hallmark of acquired immunodeficiency syndrome (AIDS) pathogenesis is a progressive depletion of CD4( …
MHC-driven HIV-1 control on the long run is not systematically determined at early times post-HIV-1 infection.
Antoni G, Guergnon J, Meaudre C, Samri A, Boufassa F, Goujard C, Lambotte O, Autran B, Rouzioux C, Costagliola D, Meyer L, Theodorou I. Antoni G, et al. AIDS. 2013 Jul 17;27(11):1707-16. doi: 10.1097/QAD.0b013e328360a4bd. AIDS. 2013. PMID: 23462218
First, the HLA B*57, HLA-B*27, HLA-B*13 and HLA-C*14 alleles, which have a strong effect on long-term disease control, also influence at least one of the early infection phenotypes. ...CONCLUSION: Our study highlighted independent effects of HLA-B and HLA-C a …
First, the HLA B*57, HLA-B*27, HLA-B*13 and HLA-C*14 alleles, which have a strong effect on long-term disease control, also influence …
Development of a G118R mutation in HIV-1 integrase following a switch to dolutegravir monotherapy leading to cross-resistance to integrase inhibitors.
Brenner BG, Thomas R, Blanco JL, Ibanescu RI, Oliveira M, Mesplède T, Golubkov O, Roger M, Garcia F, Martinez E, Wainberg MA. Brenner BG, et al. J Antimicrob Chemother. 2016 Jul;71(7):1948-53. doi: 10.1093/jac/dkw071. Epub 2016 Mar 29. J Antimicrob Chemother. 2016. PMID: 27029845 Free PMC article.
OBJECTIVES: Dolutegravir shows a high barrier to resistance with no previously reported cases of acquired integrase mutations during first-line therapy. ...Virological failure (<1000 copies/mL) emerged early within 2 months following the dolutegravir switch. The …
OBJECTIVES: Dolutegravir shows a high barrier to resistance with no previously reported cases of acquired integrase mutations during …
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