Suter L - Search Results

1

Renal biomarker qualification submission: a dialog between the FDA-EMEA and Predictive Safety Testing Consortium.

Dieterle F, Sistare F, Goodsaid F, Papaluca M, Ozer JS, Webb CP, Baer W, Senagore A, Schipper MJ, Vonderscher J, Sultana S, Gerhold DL, Phillips JA, Maurer G, Carl K, Laurie D, Harpur E, Sonee M, Ennulat D, Holder D, Andrews-Cleavenger D, Gu YZ, Thompson KL, Goering PL, Vidal JM, Abadie E, Maciulaitis R, Jacobson-Kram D, Defelice AF, Hausner EA, Blank M, Thompson A, Harlow P, Throckmorton D, Xiao S, Xu N, Taylor W, Vamvakas S, Flamion B, Lima BS, Kasper P, Pasanen M, Prasad K, Troth S, Bounous D, Robinson-Gravatt D, Betton G, Davis MA, Akunda J, McDuffie JE, Suter L, Obert L, Guffroy M, Pinches M, Jayadev S, Blomme EA, Beushausen SA, Barlow VG, Collins N, Waring J, Honor D, Snook S, Lee J, Rossi P, Walker E, Mattes W. Dieterle F, et al. Among authors: suter l. Nat Biotechnol. 2010 May;28(5):455-62. doi: 10.1038/nbt.1625. Epub 2010 May 10. Nat Biotechnol. 2010. PMID: 20458315

2

Application of metabonomics in a comparative profiling study reveals N-acetylfelinine excretion as a biomarker for inhibition of the farnesyl pathway by bisphosphonates.

Dieterle F, Schlotterbeck G, Binder M, Ross A, Suter L, Senn H. Dieterle F, et al. Among authors: suter l. Chem Res Toxicol. 2007 Sep;20(9):1291-9. doi: 10.1021/tx700151t. Epub 2007 Aug 4. Chem Res Toxicol. 2007. PMID: 17676813

3

EU framework 6 project: predictive toxicology (PredTox)--overview and outcome.

Suter L, Schroeder S, Meyer K, Gautier JC, Amberg A, Wendt M, Gmuender H, Mally A, Boitier E, Ellinger-Ziegelbauer H, Matheis K, Pfannkuch F. Suter L, et al. Toxicol Appl Pharmacol. 2011 Apr 15;252(2):73-84. doi: 10.1016/j.taap.2010.10.008. Epub 2010 Oct 16. Toxicol Appl Pharmacol. 2011. PMID: 20955723

4

Cross-study and cross-omics comparisons of three nephrotoxic compounds reveal mechanistic insights and new candidate biomarkers.

Matheis KA, Com E, Gautier JC, Guerreiro N, Brandenburg A, Gmuender H, Sposny A, Hewitt P, Amberg A, Boernsen O, Riefke B, Hoffmann D, Mally A, Kalkuhl A, Suter L, Dieterle F, Staedtler F. Matheis KA, et al. Among authors: suter l. Toxicol Appl Pharmacol. 2011 Apr 15;252(2):112-22. doi: 10.1016/j.taap.2010.11.006. Epub 2010 Nov 21. Toxicol Appl Pharmacol. 2011. PMID: 21081137

5

The enhanced value of combining conventional and "omics" analyses in early assessment of drug-induced hepatobiliary injury.

Ellinger-Ziegelbauer H, Adler M, Amberg A, Brandenburg A, Callanan JJ, Connor S, Fountoulakis M, Gmuender H, Gruhler A, Hewitt P, Hodson M, Matheis KA, McCarthy D, Raschke M, Riefke B, Schmitt CS, Sieber M, Sposny A, Suter L, Sweatman B, Mally A. Ellinger-Ziegelbauer H, et al. Among authors: suter l. Toxicol Appl Pharmacol. 2011 Apr 15;252(2):97-111. doi: 10.1016/j.taap.2010.09.022. Epub 2010 Oct 1. Toxicol Appl Pharmacol. 2011. PMID: 20888850

6

Gene expression-based in vivo and in vitro prediction of liver toxicity allows compound selection at an early stage of drug development.

Roth A, Boess F, Landes C, Steiner G, Freichel C, Plancher JM, Raab S, de Vera Mudry C, Weiser T, Suter L. Roth A, et al. Among authors: suter l. J Biochem Mol Toxicol. 2011 May-Jun;25(3):183-94. doi: 10.1002/jbt.20375. Epub 2010 Nov 12. J Biochem Mol Toxicol. 2011. PMID: 21671310

7

Toxicogenomics in predictive toxicology in drug development.

Suter L, Babiss LE, Wheeldon EB. Suter L, et al. Chem Biol. 2004 Feb;11(2):161-71. doi: 10.1016/j.chembiol.2004.02.003. Chem Biol. 2004. PMID: 15123278 Review.

8

Increased levels of urinary phenylacetylglycine associated with mitochondrial toxicity in a model of drug-induced phospholipidosis.

Doessegger L, Schmitt G, Lenz B, Fischer H, Schlotterbeck G, Atzpodien EA, Senn H, Suter L, Csato M, Evers S, Singer T. Doessegger L, et al. Among authors: suter l. Ther Adv Drug Saf. 2013 Jun;4(3):101-14. doi: 10.1177/2042098613479393. Ther Adv Drug Saf. 2013. PMID: 25083254 Free PMC article.

9

Preclinical evidence for nitrogen-containing bisphosphonate inhibition of farnesyl diphosphate (FPP) synthase in the kidney: implications for renal safety.

Lühe A, Künkele KP, Haiker M, Schad K, Zihlmann C, Bauss F, Suter L, Pfister T. Lühe A, et al. Among authors: suter l. Toxicol In Vitro. 2008 Jun;22(4):899-909. doi: 10.1016/j.tiv.2008.01.006. Epub 2008 Jan 26. Toxicol In Vitro. 2008. PMID: 18325729

10

A long-term three dimensional liver co-culture system for improved prediction of clinically relevant drug-induced hepatotoxicity.

Kostadinova R, Boess F, Applegate D, Suter L, Weiser T, Singer T, Naughton B, Roth A. Kostadinova R, et al. Among authors: suter l. Toxicol Appl Pharmacol. 2013 Apr 1;268(1):1-16. doi: 10.1016/j.taap.2013.01.012. Epub 2013 Jan 23. Toxicol Appl Pharmacol. 2013. PMID: 23352505

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