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Clonal Heterogeneity and Tumor Evolution: Past, Present, and the Future.
McGranahan N, Swanton C. McGranahan N, et al. Cell. 2017 Feb 9;168(4):613-628. doi: 10.1016/j.cell.2017.01.018. Cell. 2017. PMID: 28187284 Review.
Chromosomal instability, colorectal cancer and taxane resistance.
Swanton C, Tomlinson I, Downward J. Swanton C, et al. Cell Cycle. 2006 Apr;5(8):818-23. doi: 10.4161/cc.5.8.2682. Epub 2006 Apr 17. Cell Cycle. 2006. PMID: 16628000 Review.
Regulators of mitotic arrest and ceramide metabolism are determinants of sensitivity to paclitaxel and other chemotherapeutic drugs.
Swanton C, Marani M, Pardo O, Warne PH, Kelly G, Sahai E, Elustondo F, Chang J, Temple J, Ahmed AA, Brenton JD, Downward J, Nicke B. Swanton C, et al. Cancer Cell. 2007 Jun;11(6):498-512. doi: 10.1016/j.ccr.2007.04.011. Cancer Cell. 2007. PMID: 17560332
The extracellular matrix protein TGFBI induces microtubule stabilization and sensitizes ovarian cancers to paclitaxel.
Ahmed AA, Mills AD, Ibrahim AE, Temple J, Blenkiron C, Vias M, Massie CE, Iyer NG, McGeoch A, Crawford R, Nicke B, Downward J, Swanton C, Bell SD, Earl HM, Laskey RA, Caldas C, Brenton JD. Ahmed AA, et al. Cancer Cell. 2007 Dec;12(6):514-27. doi: 10.1016/j.ccr.2007.11.014. Cancer Cell. 2007. PMID: 18068629 Free PMC article.
Molecular classification of solid tumours: towards pathway-driven therapeutics.
Swanton C, Caldas C. Swanton C, et al. Br J Cancer. 2009 May 19;100(10):1517-22. doi: 10.1038/sj.bjc.6605031. Epub 2009 Apr 14. Br J Cancer. 2009. PMID: 19367275 Free PMC article. Review.
Chromosomal instability determines taxane response.
Swanton C, Nicke B, Schuett M, Eklund AC, Ng C, Li Q, Hardcastle T, Lee A, Roy R, East P, Kschischo M, Endesfelder D, Wylie P, Kim SN, Chen JG, Howell M, Ried T, Habermann JK, Auer G, Brenton JD, Szallasi Z, Downward J. Swanton C, et al. Proc Natl Acad Sci U S A. 2009 May 26;106(21):8671-6. doi: 10.1073/pnas.0811835106. Epub 2009 May 19. Proc Natl Acad Sci U S A. 2009. PMID: 19458043 Free PMC article.
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