Swayze EE - Search Results

1

Comprehensive Structure-Activity Relationship of Triantennary N-Acetylgalactosamine Conjugated Antisense Oligonucleotides for Targeted Delivery to Hepatocytes.

Prakash TP, Yu J, Migawa MT, Kinberger GA, Wan WB, Østergaard ME, Carty RL, Vasquez G, Low A, Chappell A, Schmidt K, Aghajan M, Crosby J, Murray HM, Booten SL, Hsiao J, Soriano A, Machemer T, Cauntay P, Burel SA, Murray SF, Gaus H, Graham MJ, Swayze EE, Seth PP. Prakash TP, et al. Among authors: swayze ee. J Med Chem. 2016 Mar 24;59(6):2718-33. doi: 10.1021/acs.jmedchem.5b01948. Epub 2016 Mar 9. J Med Chem. 2016. PMID: 26914862

2

New inhibitors of bacterial protein synthesis from a combinatorial library of macrocycles.

Jefferson EA, Arakawa S, Blyn LB, Miyaji A, Osgood SA, Ranken R, Risen LM, Swayze EE. Jefferson EA, et al. Among authors: swayze ee. J Med Chem. 2002 Aug 1;45(16):3430-9. doi: 10.1021/jm010437x. J Med Chem. 2002. PMID: 12139453

3

SAR by MS: a ligand based technique for drug lead discovery against structured RNA targets.

Swayze EE, Jefferson EA, Sannes-Lowery KA, Blyn LB, Risen LM, Arakawa S, Osgood SA, Hofstadler SA, Griffey RH. Swayze EE, et al. J Med Chem. 2002 Aug 29;45(18):3816-9. doi: 10.1021/jm0255466. J Med Chem. 2002. PMID: 12190303

4

Synthesis and evaluation of novel bacterial rRNA-binding benzimidazoles by mass spectrometry.

He Y, Yang J, Wu B, Robinson D, Sprankle K, Kung PP, Lowery K, Mohan V, Hofstadler S, Swayze EE, Griffey R. He Y, et al. Among authors: swayze ee. Bioorg Med Chem Lett. 2004 Feb 9;14(3):695-9. doi: 10.1016/j.bmcl.2003.11.031. Bioorg Med Chem Lett. 2004. PMID: 14741271

5

Synthesis and biological activity of 5-fluorotubercidin.

Wang X, Seth PP, Ranken R, Swayze EE, Migawa MT. Wang X, et al. Among authors: swayze ee. Nucleosides Nucleotides Nucleic Acids. 2004;23(1-2):161-70. doi: 10.1081/ncn-120027825. Nucleosides Nucleotides Nucleic Acids. 2004. PMID: 15043144

6

Biaryl guanidine inhibitors of in vitro HCV-IRES activity.

Jefferson EA, Seth PP, Robinson DE, Winter DK, Miyaji A, Osgood SA, Swayze EE, Risen LM. Jefferson EA, et al. Among authors: swayze ee. Bioorg Med Chem Lett. 2004 Oct 18;14(20):5139-43. doi: 10.1016/j.bmcl.2004.07.066. Bioorg Med Chem Lett. 2004. PMID: 15380215

7

Optimizing the antibacterial activity of a lead structure discovered by "SAR by MS" technology.

Jefferson EA, Seth PP, Robinson DE, Winter DK, Miyaji A, Risen LM, Osgood SA, Bertrand M, Swayze EE. Jefferson EA, et al. Among authors: swayze ee. Bioorg Med Chem Lett. 2004 Nov 1;14(21):5257-61. doi: 10.1016/j.bmcl.2004.08.033. Bioorg Med Chem Lett. 2004. PMID: 15454207

8

Aryl urea analogs with broad-spectrum antibacterial activity.

Seth PP, Ranken R, Robinson DE, Osgood SA, Risen LM, Rodgers EL, Migawa MT, Jefferson EA, Swayze EE. Seth PP, et al. Among authors: swayze ee. Bioorg Med Chem Lett. 2004 Nov 15;14(22):5569-72. doi: 10.1016/j.bmcl.2004.08.059. Bioorg Med Chem Lett. 2004. PMID: 15482926

9

Fully 2'-modified oligonucleotide duplexes with improved in vitro potency and stability compared to unmodified small interfering RNA.

Allerson CR, Sioufi N, Jarres R, Prakash TP, Naik N, Berdeja A, Wanders L, Griffey RH, Swayze EE, Bhat B. Allerson CR, et al. Among authors: swayze ee. J Med Chem. 2005 Feb 24;48(4):901-4. doi: 10.1021/jm049167j. J Med Chem. 2005. PMID: 15715458

10

Positional effect of chemical modifications on short interference RNA activity in mammalian cells.

Prakash TP, Allerson CR, Dande P, Vickers TA, Sioufi N, Jarres R, Baker BF, Swayze EE, Griffey RH, Bhat B. Prakash TP, et al. Among authors: swayze ee. J Med Chem. 2005 Jun 30;48(13):4247-53. doi: 10.1021/jm050044o. J Med Chem. 2005. PMID: 15974578

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