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Matrix elasticity directs stem cell lineage specification.
Engler AJ, Sen S, Sweeney HL, Discher DE. Engler AJ, et al. Cell. 2006 Aug 25;126(4):677-89. doi: 10.1016/j.cell.2006.06.044. Cell. 2006. PMID: 16923388
Extracellular matrix elasticity directs stem cell differentiation.
Engler AJ, Sweeney HL, Discher DE, Schwarzbauer JE. Engler AJ, et al. J Musculoskelet Neuronal Interact. 2007 Oct-Dec;7(4):335. J Musculoskelet Neuronal Interact. 2007. PMID: 18094500 No abstract available.
Upregulation of paxillin and focal adhesion signaling follows Dystroglycan Complex deletions and promotes a hypertensive state of differentiation.
Sen S, Tewari M, Zajac A, Barton E, Sweeney HL, Discher DE. Sen S, et al. Eur J Cell Biol. 2011 Feb-Mar;90(2-3):249-60. doi: 10.1016/j.ejcb.2010.06.005. Eur J Cell Biol. 2011. PMID: 20663583 Free PMC article.
Preparation of collagen-coated gels that maximize in vitro myogenesis of stem cells by matching the lateral elasticity of in vivo muscle.
Chaudhuri T, Rehfeldt F, Sweeney HL, Discher DE. Chaudhuri T, et al. Methods Mol Biol. 2010;621:185-202. doi: 10.1007/978-1-60761-063-2_13. Methods Mol Biol. 2010. PMID: 20405368 Free PMC article.
Mutation of smooth muscle myosin causes epithelial invasion and cystic expansion of the zebrafish intestine.
Wallace KN, Dolan AC, Seiler C, Smith EM, Yusuff S, Chaille-Arnold L, Judson B, Sierk R, Yengo C, Sweeney HL, Pack M. Wallace KN, et al. Dev Cell. 2005 May;8(5):717-26. doi: 10.1016/j.devcel.2005.02.015. Dev Cell. 2005. PMID: 15866162
gamma-Sarcoglycan deficiency increases cell contractility, apoptosis and MAPK pathway activation but does not affect adhesion.
Griffin MA, Feng H, Tewari M, Acosta P, Kawana M, Sweeney HL, Discher DE. Griffin MA, et al. J Cell Sci. 2005 Apr 1;118(Pt 7):1405-16. doi: 10.1242/jcs.01717. Epub 2005 Mar 15. J Cell Sci. 2005. PMID: 15769854
Adhesion-contractile balance in myocyte differentiation.
Griffin MA, Sen S, Sweeney HL, Discher DE. Griffin MA, et al. J Cell Sci. 2004 Nov 15;117(Pt 24):5855-63. doi: 10.1242/jcs.01496. Epub 2004 Nov 2. J Cell Sci. 2004. PMID: 15522893
Myotubes differentiate optimally on substrates with tissue-like stiffness: pathological implications for soft or stiff microenvironments.
Engler AJ, Griffin MA, Sen S, Bönnemann CG, Sweeney HL, Discher DE. Engler AJ, et al. J Cell Biol. 2004 Sep 13;166(6):877-87. doi: 10.1083/jcb.200405004. J Cell Biol. 2004. PMID: 15364962 Free PMC article.
Correction of the dystrophic phenotype by in vivo targeting of muscle progenitor cells.
Kobinger GP, Louboutin JP, Barton ER, Sweeney HL, Wilson JM. Kobinger GP, et al. Hum Gene Ther. 2003 Oct 10;14(15):1441-9. doi: 10.1089/104303403769211655. Hum Gene Ther. 2003. PMID: 14577924
Mesenchymal stem cell injection after myocardial infarction improves myocardial compliance.
Berry MF, Engler AJ, Woo YJ, Pirolli TJ, Bish LT, Jayasankar V, Morine KJ, Gardner TJ, Discher DE, Sweeney HL. Berry MF, et al. Am J Physiol Heart Circ Physiol. 2006 Jun;290(6):H2196-203. doi: 10.1152/ajpheart.01017.2005. Epub 2006 Feb 10. Am J Physiol Heart Circ Physiol. 2006. PMID: 16473959
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