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Plexin-B1 directly interacts with PDZ-RhoGEF/LARG to regulate RhoA and growth cone morphology.
Swiercz JM, Kuner R, Behrens J, Offermanns S. Swiercz JM, et al. Neuron. 2002 Jul 3;35(1):51-63. doi: 10.1016/s0896-6273(02)00750-x. Neuron. 2002. PMID: 12123608
Grb2 mediates semaphorin-4D-dependent RhoA inactivation.
Sun T, Krishnan R, Swiercz JM. Sun T, et al. Among authors: swiercz jm. J Cell Sci. 2012 Aug 1;125(Pt 15):3557-67. doi: 10.1242/jcs.101063. Epub 2012 Apr 14. J Cell Sci. 2012. PMID: 22505611 Free article.
ArhGEF18 regulates RhoA-Rock2 signaling to maintain neuro-epithelial apico-basal polarity and proliferation.
Herder C, Swiercz JM, Müller C, Peravali R, Quiring R, Offermanns S, Wittbrodt J, Loosli F. Herder C, et al. Among authors: swiercz jm. Development. 2013 Jul;140(13):2787-97. doi: 10.1242/dev.096487. Epub 2013 May 22. Development. 2013. PMID: 23698346 Free article.
Genetic dissection of plexin signaling in vivo.
Worzfeld T, Swiercz JM, Sentürk A, Genz B, Korostylev A, Deng S, Xia J, Hoshino M, Epstein JA, Chan AM, Vollmar B, Acker-Palmer A, Kuner R, Offermanns S. Worzfeld T, et al. Among authors: swiercz jm. Proc Natl Acad Sci U S A. 2014 Feb 11;111(6):2194-9. doi: 10.1073/pnas.1308418111. Epub 2014 Jan 27. Proc Natl Acad Sci U S A. 2014. PMID: 24469813 Free PMC article.
ErbB-2 signals through Plexin-B1 to promote breast cancer metastasis.
Worzfeld T, Swiercz JM, Looso M, Straub BK, Sivaraj KK, Offermanns S. Worzfeld T, et al. Among authors: swiercz jm. J Clin Invest. 2012 Apr;122(4):1296-305. doi: 10.1172/JCI60568. Epub 2012 Mar 1. J Clin Invest. 2012. PMID: 22378040 Free PMC article.
A reverse signaling pathway downstream of Sema4A controls cell migration via Scrib.
Sun T, Yang L, Kaur H, Pestel J, Looso M, Nolte H, Krasel C, Heil D, Krishnan RK, Santoni MJ, Borg JP, Bünemann M, Offermanns S, Swiercz JM, Worzfeld T. Sun T, et al. Among authors: swiercz jm. J Cell Biol. 2017 Jan 2;216(1):199-215. doi: 10.1083/jcb.201602002. Epub 2016 Dec 22. J Cell Biol. 2017. PMID: 28007914 Free PMC article.
Semaphorin-Plexin Signaling Controls Mitotic Spindle Orientation during Epithelial Morphogenesis and Repair.
Xia J, Swiercz JM, Bañón-Rodríguez I, Matković I, Federico G, Sun T, Franz T, Brakebusch CH, Kumanogoh A, Friedel RH, Martín-Belmonte F, Gröne HJ, Offermanns S, Worzfeld T. Xia J, et al. Among authors: swiercz jm. Dev Cell. 2015 May 4;33(3):299-313. doi: 10.1016/j.devcel.2015.02.001. Epub 2015 Apr 16. Dev Cell. 2015. PMID: 25892012 Free article.
The IκB kinase complex is required for plexin-B-mediated activation of RhoA.
Zielonka M, Krishnan RK, Swiercz JM, Offermanns S. Zielonka M, et al. Among authors: swiercz jm. PLoS One. 2014 Aug 19;9(8):e105661. doi: 10.1371/journal.pone.0105661. eCollection 2014. PLoS One. 2014. PMID: 25137062 Free PMC article.
Semaphorin 4D signaling requires the recruitment of phospholipase C gamma into the plexin-B1 receptor complex.
Swiercz JM, Worzfeld T, Offermanns S. Swiercz JM, et al. Mol Cell Biol. 2009 Dec;29(23):6321-34. doi: 10.1128/MCB.00103-09. Epub 2009 Oct 5. Mol Cell Biol. 2009. PMID: 19805522 Free PMC article.
The semaphorin 4D-plexin-B signalling complex regulates dendritic and axonal complexity in developing neurons via diverse pathways.
Vodrazka P, Korostylev A, Hirschberg A, Swiercz JM, Worzfeld T, Deng S, Fazzari P, Tamagnone L, Offermanns S, Kuner R. Vodrazka P, et al. Among authors: swiercz jm. Eur J Neurosci. 2009 Oct;30(7):1193-208. doi: 10.1111/j.1460-9568.2009.06934.x. Epub 2009 Sep 29. Eur J Neurosci. 2009. PMID: 19788569
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