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Biochemical, single-channel, whole-cell patch clamp, and pharmacological analyses of endogenous TRPM4 channels in HEK293 cells.
Amarouch MY, Syam N, Abriel H. Amarouch MY, et al. Among authors: syam n. Neurosci Lett. 2013 Apr 29;541:105-10. doi: 10.1016/j.neulet.2013.02.011. Epub 2013 Feb 18. Neurosci Lett. 2013. PMID: 23428507
β1- and β3- voltage-gated sodium channel subunits modulate cell surface expression and glycosylation of Nav1.7 in HEK293 cells.
Laedermann CJ, Syam N, Pertin M, Decosterd I, Abriel H. Laedermann CJ, et al. Among authors: syam n. Front Cell Neurosci. 2013 Aug 30;7:137. doi: 10.3389/fncel.2013.00137. eCollection 2013. Front Cell Neurosci. 2013. PMID: 24009557 Free PMC article.
Glycosylation of TRPM4 and TRPM5 channels: molecular determinants and functional aspects.
Syam N, Rougier JS, Abriel H. Syam N, et al. Front Cell Neurosci. 2014 Feb 24;8:52. doi: 10.3389/fncel.2014.00052. eCollection 2014. Front Cell Neurosci. 2014. PMID: 24605085 Free PMC article.
Variants of Transient Receptor Potential Melastatin Member 4 in Childhood Atrioventricular Block.
Syam N, Chatel S, Ozhathil LC, Sottas V, Rougier JS, Baruteau A, Baron E, Amarouch MY, Daumy X, Probst V, Schott JJ, Abriel H. Syam N, et al. J Am Heart Assoc. 2016 May 20;5(5):e001625. doi: 10.1161/JAHA.114.001625. J Am Heart Assoc. 2016. PMID: 27207958 Free PMC article.
The Ca(2+)-activated cation channel TRPM4 is a negative regulator of angiotensin II-induced cardiac hypertrophy.
Kecskés M, Jacobs G, Kerselaers S, Syam N, Menigoz A, Vangheluwe P, Freichel M, Flockerzi V, Voets T, Vennekens R. Kecskés M, et al. Among authors: syam n. Basic Res Cardiol. 2015;110(4):43. doi: 10.1007/s00395-015-0501-x. Epub 2015 Jun 5. Basic Res Cardiol. 2015. PMID: 26043922 Free PMC article.
TRPM4 channels in the cardiovascular system: physiology, pathophysiology, and pharmacology.
Abriel H, Syam N, Sottas V, Amarouch MY, Rougier JS. Abriel H, et al. Among authors: syam n. Biochem Pharmacol. 2012 Oct 1;84(7):873-81. doi: 10.1016/j.bcp.2012.06.021. Epub 2012 Jun 27. Biochem Pharmacol. 2012. PMID: 22750058 Review.
Molecular genetics and functional anomalies in a series of 248 Brugada cases with 11 mutations in the TRPM4 channel.
Liu H, Chatel S, Simard C, Syam N, Salle L, Probst V, Morel J, Millat G, Lopez M, Abriel H, Schott JJ, Guinamard R, Bouvagnet P. Liu H, et al. Among authors: syam n. PLoS One. 2013;8(1):e54131. doi: 10.1371/journal.pone.0054131. Epub 2013 Jan 30. PLoS One. 2013. PMID: 23382873 Free PMC article.
Muscling in on TRP channels in vascular smooth muscle cells and cardiomyocytes.
Alonso-Carbajo L, Kecskes M, Jacobs G, Pironet A, Syam N, Talavera K, Vennekens R. Alonso-Carbajo L, et al. Among authors: syam n. Cell Calcium. 2017 Sep;66:48-61. doi: 10.1016/j.ceca.2017.06.004. Epub 2017 Jun 15. Cell Calcium. 2017. PMID: 28807149 Review.
PDZ domain-binding motif regulates cardiomyocyte compartment-specific NaV1.5 channel expression and function.
Shy D, Gillet L, Ogrodnik J, Albesa M, Verkerk AO, Wolswinkel R, Rougier JS, Barc J, Essers MC, Syam N, Marsman RF, van Mil AM, Rotman S, Redon R, Bezzina CR, Remme CA, Abriel H. Shy D, et al. Among authors: syam n. Circulation. 2014 Jul 8;130(2):147-60. doi: 10.1161/CIRCULATIONAHA.113.007852. Epub 2014 Jun 3. Circulation. 2014. PMID: 24895455
AAV9-Mediated Overexpression of TRPM4 Increases the Incidence of Stress-Induced Ventricular Arrhythmias in Mice.
Pironet A, Syam N, Vandewiele F, Van den Haute C, Kerselaers S, Pinto S, Vande Velde G, Gijsbers R, Vennekens R. Pironet A, et al. Among authors: syam n. Front Physiol. 2019 Jun 27;10:802. doi: 10.3389/fphys.2019.00802. eCollection 2019. Front Physiol. 2019. PMID: 31316392 Free PMC article.
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