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Elucidating the path to Plasmodium prolyl-tRNA synthetase inhibitors that overcome halofuginone resistance.
Tye MA, Payne NC, Johansson C, Singh K, Santos SA, Fagbami L, Pant A, Sylvester K, Luth MR, Marques S, Whitman M, Mota MM, Winzeler EA, Lukens AK, Derbyshire ER, Oppermann U, Wirth DF, Mazitschek R. Tye MA, et al. Among authors: sylvester k. Nat Commun. 2022 Aug 25;13(1):4976. doi: 10.1038/s41467-022-32630-4. Nat Commun. 2022. PMID: 36008486 Free PMC article.
Plasmodium parasite exploits host aquaporin-3 during liver stage malaria infection.
Posfai D, Sylvester K, Reddy A, Ganley JG, Wirth J, Cullen QE, Dave T, Kato N, Dave SS, Derbyshire ER. Posfai D, et al. Among authors: sylvester k. PLoS Pathog. 2018 May 18;14(5):e1007057. doi: 10.1371/journal.ppat.1007057. eCollection 2018 May. PLoS Pathog. 2018. PMID: 29775485 Free PMC article.
A Systematic Analysis of Mosquito-Microbiome Biosynthetic Gene Clusters Reveals Antimalarial Siderophores that Reduce Mosquito Reproduction Capacity.
Ganley JG, Pandey A, Sylvester K, Lu KY, Toro-Moreno M, Rütschlin S, Bradford JM, Champion CJ, Böttcher T, Xu J, Derbyshire ER. Ganley JG, et al. Among authors: sylvester k. Cell Chem Biol. 2020 Jul 16;27(7):817-826.e5. doi: 10.1016/j.chembiol.2020.06.004. Epub 2020 Jul 2. Cell Chem Biol. 2020. PMID: 32619453 Free article.
316 results