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Sympathetic hyperactivity in chronic kidney disease: pathophysiology and (new) treatment options.
Vink EE, de Jager RL, Blankestijn PJ. Vink EE, et al. Curr Hypertens Rep. 2013 Apr;15(2):95-101. doi: 10.1007/s11906-013-0328-5. Curr Hypertens Rep. 2013. PMID: 23354877 Review.
Abundant evidence shows that chronic kidney disease (CKD) is a disease state characterized by increased sympathetic activation. ...This current report focuses on the effects of sympathetic hyperactivity in CKD, and gives an overvie …
Abundant evidence shows that chronic kidney disease (CKD) is a disease state characterized by increased sympa
The role of renal denervation for the treatment of hypertension in patients with chronic kidney disease: a position paper of the Italian Society of Nephrology.
Feriozzi S, Battaglia Y, Cirami CL, Gangemi C, La Manna G, Gesualdo L, Muiesan ML, Pani A, Pieruzzi F, Ribichini F, Taddei S, Bianchi S. Feriozzi S, et al. J Nephrol. 2025 Nov;38(8):2053-2065. doi: 10.1007/s40620-025-02406-2. Epub 2025 Sep 8. J Nephrol. 2025. PMID: 40920285 Free PMC article. Review.
Hypertension is a clinical condition associated with an increase in cardiovascular morbidity and mortality. In chronic kidney disease (CKD), hypertension is also a driver of faster disease progression. Correct and appropriate treatment with anti …
Hypertension is a clinical condition associated with an increase in cardiovascular morbidity and mortality. In chronic kidney
Sympathetic hyperactivity in chronic renal failure: a wake-up call.
Koomans HA, Blankestijn PJ, Joles JA. Koomans HA, et al. J Am Soc Nephrol. 2004 Mar;15(3):524-37. doi: 10.1097/01.asn.0000113320.57127.b9. J Am Soc Nephrol. 2004. PMID: 14978154 Review.
Sympathetic hyperactivity plays an important and distinct role in hypertension associated with chronic renal failure (CRF). ...Evidence is accumulating for a role of sympathetic hyperactivity in renal and cardiac damage in patients
Sympathetic hyperactivity plays an important and distinct role in hypertension associated with chronic renal fai
Evidence and consequences of the central role of the kidneys in the pathophysiology of sympathetic hyperactivity.
Vink EE, Blankestijn PJ. Vink EE, et al. Front Physiol. 2012 Feb 20;3:29. doi: 10.3389/fphys.2012.00029. eCollection 2012. Front Physiol. 2012. PMID: 22363298 Free PMC article.
Chronic elevation of the sympathetic nervous system has been identified as a major contributor to the complex pathophysiology of hypertension, states of volume overload - such as heart failure - and progressive kidney disease. ...This review foc
Chronic elevation of the sympathetic nervous system has been identified as a major contributor to the complex pathophysiolo