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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1946 1
1947 2
1951 2
1952 2
1953 1
1954 1
1955 4
1956 5
1957 5
1958 3
1959 3
1960 3
1961 9
1962 4
1963 21
1964 41
1965 45
1966 82
1967 113
1968 163
1969 184
1970 193
1971 321
1972 341
1973 340
1974 356
1975 376
1976 451
1977 452
1978 467
1979 557
1980 656
1981 589
1982 717
1983 775
1984 734
1985 740
1986 727
1987 668
1988 668
1989 801
1990 883
1991 912
1992 981
1993 1164
1994 1119
1995 1139
1996 1187
1997 1194
1998 1365
1999 1473
2000 1699
2001 1846
2002 2070
2003 2063
2004 2084
2005 2136
2006 2461
2007 2427
2008 2580
2009 2635
2010 2806
2011 2869
2012 2918
2013 3017
2014 2877
2015 2760
2016 2744
2017 2777
2018 2693
2019 2522
2020 2524
2021 2579
2022 1951
2023 514
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74,693 results
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Page 1
The cell biology of synapse formation.
Südhof TC. Südhof TC. J Cell Biol. 2021 Jul 5;220(7):e202103052. doi: 10.1083/jcb.202103052. Epub 2021 Jun 4. J Cell Biol. 2021. PMID: 34086051 Free PMC article. Review.
Here, I posit that synaptic adhesion molecules (SAMs) organize synapse formation. Diverse SAMs collaborate to achieve the astounding specificity and plasticity of synapses, with each SAM contributing different facets. ...Although many candidate SAMs are known …
Here, I posit that synaptic adhesion molecules (SAMs) organize synapse formation. Diverse SAMs collaborate to achieve the asto …
Synapse formation: from cellular and molecular mechanisms to neurodevelopmental and neurodegenerative disorders.
Batool S, Raza H, Zaidi J, Riaz S, Hasan S, Syed NI. Batool S, et al. J Neurophysiol. 2019 Apr 1;121(4):1381-1397. doi: 10.1152/jn.00833.2018. Epub 2019 Feb 13. J Neurophysiol. 2019. PMID: 30759043 Free article. Review.
Thus, synapse formation is not restricted to neurodevelopment; it is a process that remains active throughout life. ...This review seeks to highlight salient steps that are involved in a neuron's journey, starting with the establishment, maturation, and conso …
Thus, synapse formation is not restricted to neurodevelopment; it is a process that remains active throughout life. ...This re …
Latrophilin GPCR signaling mediates synapse formation.
Sando R, Südhof TC. Sando R, et al. Elife. 2021 Mar 1;10:e65717. doi: 10.7554/eLife.65717. Elife. 2021. PMID: 33646123 Free PMC article.
In mouse CA1-region neurons, Latrophilin-2 and Latrophilin-3 are essential for formation of entorhinal-cortex-derived and Schaffer-collateral-derived synapses, respectively. ...Our results suggest that Latrophilin-2 and Latrophilin-3 require GPCR signaling in syn …
In mouse CA1-region neurons, Latrophilin-2 and Latrophilin-3 are essential for formation of entorhinal-cortex-derived and Schaffer-co …
Astrocytes Control Synapse Formation, Function, and Elimination.
Chung WS, Allen NJ, Eroglu C. Chung WS, et al. Cold Spring Harb Perspect Biol. 2015 Feb 6;7(9):a020370. doi: 10.1101/cshperspect.a020370. Cold Spring Harb Perspect Biol. 2015. PMID: 25663667 Free PMC article. Review.
In this article, we will review the key findings on astrocytic control of synapse formation, function, and elimination. First, we will summarize our current structural and functional understanding of astrocytes at the synapse. Then, we will discuss the cellul …
In this article, we will review the key findings on astrocytic control of synapse formation, function, and elimination. First, …
A Presynaptic Perspective on Transport and Assembly Mechanisms for Synapse Formation.
Rizalar FS, Roosen DA, Haucke V. Rizalar FS, et al. Neuron. 2021 Jan 6;109(1):27-41. doi: 10.1016/j.neuron.2020.09.038. Epub 2020 Oct 23. Neuron. 2021. PMID: 33098763 Free article. Review.
In contrast with the significant progress that has been made in understanding synaptic transmission and processing of information at the post-synapse, comparably little is known about the formation and dynamic remodeling of the presynaptic compartment. ...
In contrast with the significant progress that has been made in understanding synaptic transmission and processing of information at the pos …
Latrophilin GPCRs direct synapse specificity by coincident binding of FLRTs and teneurins.
Sando R, Jiang X, Südhof TC. Sando R, et al. Science. 2019 Feb 22;363(6429):eaav7969. doi: 10.1126/science.aav7969. Science. 2019. PMID: 30792275 Free PMC article.
Bidirectional signaling by cell adhesion molecules is thought to mediate synapse formation, but the mechanisms involved remain elusive. We found that the adhesion G protein-coupled receptors latrophilin-2 and latrophilin-3 selectively direct formation of perf …
Bidirectional signaling by cell adhesion molecules is thought to mediate synapse formation, but the mechanisms involved remain …
[Synapse formation and regeneration].
d'Houtaud S, Sztermer E, Buffenoir K, Giot JP, Wager M, Bauche S, Lapierre F, Rigoard P. d'Houtaud S, et al. Neurochirurgie. 2009 Mar;55 Suppl 1:S49-62. doi: 10.1016/j.neuchi.2008.03.014. Epub 2009 Feb 20. Neurochirurgie. 2009. PMID: 19230939 Review. French.
Synapse formation is probably the key process in neural development allowing signal transmission between nerve cells. ...The initial steps of this differentiation and motor endplate formation require several postsynaptic molecular agents including agrin, the …
Synapse formation is probably the key process in neural development allowing signal transmission between nerve cells. ...The i …
Phase separation at the synapse.
Chen X, Wu X, Wu H, Zhang M. Chen X, et al. Nat Neurosci. 2020 Mar;23(3):301-310. doi: 10.1038/s41593-019-0579-9. Epub 2020 Feb 3. Nat Neurosci. 2020. PMID: 32015539 Review.
Emerging evidence indicates that liquid-liquid phase separation, the formation of a condensed molecular assembly within another diluted aqueous solution, is a means for cells to organize highly condensed biological assemblies (also known as biological condensates or membra …
Emerging evidence indicates that liquid-liquid phase separation, the formation of a condensed molecular assembly within another dilut …
Mechanism of Oxidative Stress and Synapse Dysfunction in the Pathogenesis of Alzheimer's Disease: Understanding the Therapeutics Strategies.
Kamat PK, Kalani A, Rai S, Swarnkar S, Tota S, Nath C, Tyagi N. Kamat PK, et al. Mol Neurobiol. 2016 Jan;53(1):648-661. doi: 10.1007/s12035-014-9053-6. Epub 2014 Dec 17. Mol Neurobiol. 2016. PMID: 25511446 Free PMC article. Review.
This passage usually gets damaged or lost in most of the neurodegenerative diseases. It is widely believed that the synaptic dysfunction and synapse loss contribute to the cognitive deficits in patients with Alzheimer's disease (AD). ...NMDARs maintain neuronal exci …
This passage usually gets damaged or lost in most of the neurodegenerative diseases. It is widely believed that the synaptic dysfunction and …
74,693 results
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