Synergistic signals for natural cytotoxicity are required to overcome inhibition by c-Cbl ubiquitin ligase.
Immunity. 2010.
PMID: 20189481
Free PMC article.
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Synergistic signals for natural cytotoxicity are required to overcome inhibition by c-Cbl ubiquitin ligase.
Kim HS, Das A, Gross CC, Bryceson YT, Long EO.
Kim HS, et al.
Immunity. 2010 Feb 26;32(2):175-86. doi: 10.1016/j.immuni.2010.02.004.
Immunity. 2010.
PMID: 20189481
Free PMC article.
Thus, synergy requires not strict complementation but, rather, strong Vav1 signals to overcome inhibition by c-Cbl. Inhibition of NK cell cytotoxicity by CD94-NKG2A binding to HLA-E on target cells was dominant over syner …
Thus, synergy requires not strict complementation but, rather, strong Vav1 signals to overcome inhibition by …
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Complementary phosphorylation sites in the adaptor protein SLP-76 promote synergistic activation of natural killer cells.
Kim HS, Long EO.
Kim HS, et al.
Sci Signal. 2012 Jul 10;5(232):ra49. doi: 10.1126/scisignal.2002754.
Sci Signal. 2012.
PMID: 22786724
Free PMC article.
The cytotoxic effects of natural killer (NK) cells and their ability to secrete cytokines require synergistic signals from specific pairs of co-activation receptors, such as CD314 (also known as NKG2D) and CD244 (2B4), which bind to distinct lig …
The cytotoxic effects of natural killer (NK) cells and their ability to secrete cytokines require synergistic …
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