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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1947 1
1971 4
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1974 1
1975 6
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1978 10
1979 5
1980 7
1981 9
1982 4
1983 8
1984 6
1985 8
1986 4
1987 2
1988 2
1989 5
1990 8
1991 10
1992 10
1993 13
1994 9
1995 17
1996 13
1997 24
1998 35
1999 36
2000 43
2001 53
2002 49
2003 53
2004 53
2005 71
2006 70
2007 89
2008 79
2009 82
2010 99
2011 137
2012 181
2013 207
2014 243
2015 279
2016 376
2017 347
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2026 68

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Page 1
Synthetic cannabinoids: epidemiology, pharmacodynamics, and clinical implications.
Castaneto MS, Gorelick DA, Desrosiers NA, Hartman RL, Pirard S, Huestis MA. Castaneto MS, et al. Drug Alcohol Depend. 2014 Nov 1;144:12-41. doi: 10.1016/j.drugalcdep.2014.08.005. Epub 2014 Aug 18. Drug Alcohol Depend. 2014. PMID: 25220897 Free PMC article. Review.
BACKGROUND: Synthetic cannabinoids (SC) are a heterogeneous group of compounds developed to probe the endogenous cannabinoid system or as potential therapeutics. ...In the early 2000s, SC became popular as "legal highs" under brand names such as Spice and K2, …
BACKGROUND: Synthetic cannabinoids (SC) are a heterogeneous group of compounds developed to probe the endogenous cannabinoi
Synthetic Cannabinoids.
Mills B, Yepes A, Nugent K. Mills B, et al. Am J Med Sci. 2015 Jul;350(1):59-62. doi: 10.1097/MAJ.0000000000000466. Am J Med Sci. 2015. PMID: 26132518 Review.
Synthetic cannabinoids (SCBs), also known under the brand names of "Spice," "K2," "herbal incense," "Cloud 9," "Mojo" and many others, are becoming a large public health concern due not only to their increasing use but also to their unpredictable toxicity and abuse
Synthetic cannabinoids (SCBs), also known under the brand names of "Spice," "K2," "herbal incense," "Cloud 9," "Mojo" and many
[Toxicology of synthetic cannabinoids].
Mouraouakkil Y, Mounir R, El Cadi MA, Lamsaouri J, Bousliman Y, ElJaoudi R. Mouraouakkil Y, et al. Ann Biol Clin (Paris). 2024 Jun 5;82(2):151-173. doi: 10.1684/abc.2024.1888. Ann Biol Clin (Paris). 2024. PMID: 38721719 Review. French.
Synthetic cannabinoids (CS), or synthetic endocannabinoid receptor agonists, were initially synthesized for basic research into exocannabinoid signaling pathways, as well as in clinical research for their analgesic properties. The use of CS for recreational p
Synthetic cannabinoids (CS), or synthetic endocannabinoid receptor agonists, were initially synthesized for basic resea
Synthetic cannabinoids and ST elevation myocardial infarction.
Jafry AH, LaGrow A, Akhtar KH, Hacker E, Russell S, Kliewer B, Asad ZUA. Jafry AH, et al. Am J Med Sci. 2022 Oct;364(4):481-491. doi: 10.1016/j.amjms.2022.05.001. Epub 2022 May 8. Am J Med Sci. 2022. PMID: 35545143 Review.
Synthetic cannabinoids cannot be detected on a standard urine drug screen (UDS), making them a convenient drug of abuse. ...We highlight STEMI as a potentially lethal complication of synthetic cannabinoids; prompt angiography may be lifesaving....
Synthetic cannabinoids cannot be detected on a standard urine drug screen (UDS), making them a convenient drug of abuse. ...We
Synthetic cannabinoids are substrates and inhibitors of multiple drug-metabolizing enzymes.
Kong TY, Kim JH, Kim DK, Lee HS. Kong TY, et al. Arch Pharm Res. 2018 Jul;41(7):691-710. doi: 10.1007/s12272-018-1055-x. Epub 2018 Jul 23. Arch Pharm Res. 2018. PMID: 30039377 Review.
The inhibitory effects of synthetic cannabinoids on CYP and UGT activities are also reviewed to predict the potential of synthetic cannabinoids for drug-drug interactions. The drug-metabolizing enzymes responsible for metabolism of synthetic
The inhibitory effects of synthetic cannabinoids on CYP and UGT activities are also reviewed to predict the potential of sy
Synthetic Cannabinoids: Psychopharmacology, Clinical Aspects, Psychotic Onset.
Martinotti G, Santacroce R, Papanti D, Elgharably Y, Prilutskaya M, Corazza O. Martinotti G, et al. CNS Neurol Disord Drug Targets. 2017;16(5):567-575. doi: 10.2174/1871527316666170413101839. CNS Neurol Disord Drug Targets. 2017. PMID: 28412921 Review.
BACKGROUND: Synthetic Cannabinoids (SC) are the widest and most diffused class of Novel Psychoactive Substances. ...METHOD: A structured search of two bibliographic databases (PubMed and Scopus) was undertaken according to inclusion/exclusion criteria. The following …
BACKGROUND: Synthetic Cannabinoids (SC) are the widest and most diffused class of Novel Psychoactive Substances. ...METHOD: A …
Synthetic cannabinoids: analysis and metabolites.
Elsohly MA, Gul W, Wanas AS, Radwan MM. Elsohly MA, et al. Life Sci. 2014 Feb 27;97(1):78-90. doi: 10.1016/j.lfs.2013.12.212. Epub 2014 Jan 8. Life Sci. 2014. PMID: 24412391 Review.
Cannabimimetics (commonly referred to as synthetic cannabinoids), a group of compounds encompassing a wide range of chemical structures, have been developed by scientists with the hope of achieving selectivity toward one or the other of the cannabinoid recept …
Cannabimimetics (commonly referred to as synthetic cannabinoids), a group of compounds encompassing a wide range of chemical s …
Synthetic cannabinoids: the hidden side of Spice drugs.
Pintori N, Loi B, Mereu M. Pintori N, et al. Behav Pharmacol. 2017 Sep;28(6):409-419. doi: 10.1097/FBP.0000000000000323. Behav Pharmacol. 2017. PMID: 28692429 Review.
The aim of this review is to gain insights into the epidemiological, pharmacological and toxicological properties of synthetic cannabinoids, aiming to provide a reliable background needed for the management of synthetic cannabinoid-related adverse effe …
The aim of this review is to gain insights into the epidemiological, pharmacological and toxicological properties of synthetic can
The synthetic cannabinoids phenomenon: from structure to toxicological properties. A review.
Alves VL, Gonçalves JL, Aguiar J, Teixeira HM, Câmara JS. Alves VL, et al. Crit Rev Toxicol. 2020 May;50(5):359-382. doi: 10.1080/10408444.2020.1762539. Epub 2020 Jun 12. Crit Rev Toxicol. 2020. PMID: 32530350 Review.
The word "cannabinoid" refers to every chemical substance, regardless of structure or origin, that joins the cannabinoid receptors of the body and brain and that have similar effects to those produced by the Cannabis plant and based on their source of production, …
The word "cannabinoid" refers to every chemical substance, regardless of structure or origin, that joins the cannabinoid recep …
The synthetic cannabinoids menace: a review of health risks and toxicity.
Alzu'bi A, Almahasneh F, Khasawneh R, Abu-El-Rub E, Baker WB, Al-Zoubi RM. Alzu'bi A, et al. Eur J Med Res. 2024 Jan 12;29(1):49. doi: 10.1186/s40001-023-01443-6. Eur J Med Res. 2024. PMID: 38216984 Free PMC article. Review.
Synthetic cannabinoids (SCs) are chemically classified as psychoactive substances that target the endocannabinoid system in many body organs. ...The majority of SCs-related side effects are mediated by activating Cannabinoid Receptor 1 (CB1R) and Cannabino
Synthetic cannabinoids (SCs) are chemically classified as psychoactive substances that target the endocannabinoid system in ma
4,818 results