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Page 1
Anticancer Potential of Pyridoxine-Based Doxorubicin Derivatives: An In Vitro Study.
Karwt R, Bondar OV, Pugachev MV, Mohammad T, Kadyrova AS, Pavelyev RS, Alrhmoun S, Gnezdilov OI, Shtyrlin YG. Karwt R, et al. Life (Basel). 2024 Feb 20;14(3):282. doi: 10.3390/life14030282. Life (Basel). 2024. PMID: 38541608
Of these two compounds, DOX-2, in which the pyridoxine fragment is attached to the doxorubicin molecule via a C3 linker, revealed higher selectivity against specific cancer cell types compared to doxorubicin and a promising safety profile for conditionally normal cells. .. …
Of these two compounds, DOX-2, in which the pyridoxine fragment is attached to the doxorubicin molecule via a C3 linker, revealed hig …
Erythema Multiforme-Like Fixed Drug Eruption During Azathioprine and Hydroxychloroquine Treatment for Systemic Lupus Erythematosus Mimicking Rowell Syndrome: A Rare and Challenging Clinical Scenario.
Shaker N, Sangueza OP, Shaker N, Arthur M, Pradhan D. Shaker N, et al. Int J Surg Pathol. 2024 Mar 18:10668969241234316. doi: 10.1177/10668969241234316. Online ahead of print. Int J Surg Pathol. 2024. PMID: 38494929
The patient had a significant past medical history of systemic lupus erythematous with positive (ANA, Sm, dsDNA, ribosomalP, RNP) antibodies, hypocomplementemia, inflammatory arthritis, discoid lupus, leukopenia, thrombocytopenia, and immune thrombocytopenic purpura, and a …
The patient had a significant past medical history of systemic lupus erythematous with positive (ANA, Sm, dsDNA, ribosomalP, RNP) ant …
Association of urine autoantibodies with disease activity in systemic lupus erythematosus.
Zhang Y, Qu X, Wang L, Song L. Zhang Y, et al. Front Med (Lausanne). 2024 Jan 19;11:1346609. doi: 10.3389/fmed.2024.1346609. eCollection 2024. Front Med (Lausanne). 2024. PMID: 38314205 Free PMC article.

Compared to the uANA negative group, the positive group exhibited significantly higher SLEDAI-2000 scores (7.85 5.88 vs. 18.69 6.93, p < 0.001), RSLEDAI scores [0 (0, 4.0) vs. 12.0 (8.0, 16.0), p < 0.001], and NRSLEDAI [4 (2.0, 8.0) vs. 6.0 (4.0, 9.5), p = 0.038]. Patients

Compared to the uANA negative group, the positive group exhibited significantly higher SLEDAI-2000 scores (7.85 5.88 vs. 18.69 6.93, p < …
Identification of pattern recognition receptor genes in peripheral blood mononuclear cells and monocytes as biomarkers for the diagnosis of lupus nephritis.
Ke PF, Zhu YT, Cao SL, Wang Y, Wu ST, He QQ, Liang LF, Li JC. Ke PF, et al. Clin Chim Acta. 2024 Feb 1;554:117785. doi: 10.1016/j.cca.2024.117785. Epub 2024 Jan 14. Clin Chim Acta. 2024. PMID: 38228224
In addition, the expression levels of these PRRs were correlated with other clinical features in LN patients, including Anti-Sm, ESR, serum Cr, and C3. CONCLUSION: Our study suggests that these lupus-related PRRs might be served as potential biomarkers of LN....
In addition, the expression levels of these PRRs were correlated with other clinical features in LN patients, including Anti-Sm, ESR, …
An Atypical Initial Manifestation of Systemic Lupus Erythematosus: Lupus Enteritis Accompanied by Intestinal Pseudo-Obstruction and Bilateral Hydronephroureter.
Naeem F, Noor MU, Batool S, Anwer Khan SE, Akmal M. Naeem F, et al. Cureus. 2023 Dec 16;15(12):e50628. doi: 10.7759/cureus.50628. eCollection 2023 Dec. Cureus. 2023. PMID: 38226118 Free PMC article.
Her labs revealed positive anti-nucleosome antibodies (8 U/mL), anti-Ro antibodies (100 U/mL), and anti-La antibodies (53 U/mL); equivocal anti-dsDNA antibodies (7 U/mL) and anti-Sm antibodies (7 U/mL); direct Coomb's positive hemolytic anemia; raised C-reactive protein an …
Her labs revealed positive anti-nucleosome antibodies (8 U/mL), anti-Ro antibodies (100 U/mL), and anti-La antibodies (53 U/mL); equivocal a …
Predictors of renal flares in systemic lupus erythematosus: a post-hoc analysis of four phase III clinical trials of belimumab.
Jägerback S, Gomez A, Parodis I. Jägerback S, et al. Rheumatology (Oxford). 2024 Jan 12:keae023. doi: 10.1093/rheumatology/keae023. Online ahead of print. Rheumatology (Oxford). 2024. PMID: 38216728
CONCLUSION: A history of renal involvement, high baseline proteinuria, hypoalbuminaemia, and C3 consumption were robust determinants of impending renal flares. Beyond anti-dsDNA, anti-Sm and anti-ribosomal P protein antibody positivity may have value in surveillance …
CONCLUSION: A history of renal involvement, high baseline proteinuria, hypoalbuminaemia, and C3 consumption were robust determinants …
Lupus erythematosus cells in a bone marrow aspirate.
Zhang J, Tan B, Fernandez-Pol S. Zhang J, et al. J Hematop. 2023 Dec;16(4):247-248. doi: 10.1007/s12308-023-00561-8. Epub 2023 Oct 2. J Hematop. 2023. PMID: 38175431
Subsequent serologic testing was positive for ANA (1:1280), low C3/C4, anti-dsDNA, anti-SM and anti-B2GP1. A kidney biopsy demonstrated findings consistent with class III lupus nephritis....
Subsequent serologic testing was positive for ANA (1:1280), low C3/C4, anti-dsDNA, anti-SM and anti-B2GP1. A kidney biopsy dem …
Dye Degradation, Antimicrobial Activity, and Molecular Docking Analysis of Samarium-Grafted Carbon Nitride Doped-Bismuth Oxobromide Quantum Dots.
Rani S, Imran M, Haider A, Shahzadi A, Ul-Hamid A, Somaily HH, Moeen S, Khan M, Nabgan W, Ikram M. Rani S, et al. Glob Chall. 2023 Nov 10;7(12):2300118. doi: 10.1002/gch2.202300118. eCollection 2023 Dec. Glob Chall. 2023. PMID: 38094862 Free PMC article.
TEM revealed that pure BiOBr possessed non-uniform QDS, and agglomeration increased with the addition of Sm-g-C(3)N(4). The catalytic performance of Sm-g-C(3)N(4) into BiOBr (6 mL) in a neutral medium toward rhodamine B exhibited excellent results (99.66%). ...Molec …
TEM revealed that pure BiOBr possessed non-uniform QDS, and agglomeration increased with the addition of Sm-g-C(3)N(4). The catalytic …
363 results