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Targeting multidrug resistance in cancer.
Szakács G, Paterson JK, Ludwig JA, Booth-Genthe C, Gottesman MM. Szakács G, et al. Nat Rev Drug Discov. 2006 Mar;5(3):219-34. doi: 10.1038/nrd1984. Nat Rev Drug Discov. 2006. PMID: 16518375 Review.
Parallel functional and immunological detection of human multidrug resistance proteins, P-glycoprotein and MRP1.
Holló Z, Homolya L, Hegedûs T, Müller M, Szakács G, Jakab K, Antal F, Sarkadi B. Holló Z, et al. Among authors: szakacs g. Anticancer Res. 1998 Jul-Aug;18(4C):2981-7. Anticancer Res. 1998. PMID: 9713496
Functional multidrug resistance protein (MRP1) lacking the N-terminal transmembrane domain.
Bakos E, Evers R, Szakács G, Tusnády GE, Welker E, Szabó K, de Haas M, van Deemter L, Borst P, Váradi A, Sarkadi B. Bakos E, et al. Among authors: szakacs g. J Biol Chem. 1998 Nov 27;273(48):32167-75. doi: 10.1074/jbc.273.48.32167. J Biol Chem. 1998. PMID: 9822694
Diagnostics of multidrug resistance in cancer.
Szakács G, Jakab K, Antal F, Sarkadi B. Szakács G, et al. Pathol Oncol Res. 1998;4(4):251-7. doi: 10.1007/BF02905214. Pathol Oncol Res. 1998. PMID: 9887354 Review.
Nucleotide occlusion in the human cystic fibrosis transmembrane conductance regulator. Different patterns in the two nucleotide binding domains.
Szabó K, Szakács G, Hegeds T, Sarkadi B. Szabó K, et al. Among authors: szakacs g. J Biol Chem. 1999 Apr 30;274(18):12209-12. doi: 10.1074/jbc.274.18.12209. J Biol Chem. 1999. PMID: 10212185
Transition-state formation in ATPase-negative mutants of human MDR1 protein.
Szakács G, Ozvegy C, Bakos E, Sarkadi B, Váradi A. Szakács G, et al. Biochem Biophys Res Commun. 2000 Oct 5;276(3):1314-9. doi: 10.1006/bbrc.2000.3576. Biochem Biophys Res Commun. 2000. PMID: 11027628
Characterization of the amino-terminal regions in the human multidrug resistance protein (MRP1).
Bakos E, Evers R, Calenda G, Tusnády GE, Szakács G, Váradi A, Sarkadi B. Bakos E, et al. Among authors: szakacs g. J Cell Sci. 2000 Dec;113 Pt 24:4451-61. J Cell Sci. 2000. PMID: 11082039
Calcein assay for multidrug resistance reliably predicts therapy response and survival rate in acute myeloid leukaemia.
Karászi E, Jakab K, Homolya L, Szakács G, Holló Z, Telek B, Kiss A, Rejtô L, Nahajevszky S, Sarkadi B, Kappelmayer J. Karászi E, et al. Among authors: szakacs g. Br J Haematol. 2001 Feb;112(2):308-14. doi: 10.1046/j.1365-2141.2001.02554.x. Br J Haematol. 2001. PMID: 11167823
Role of glycine-534 and glycine-1179 of human multidrug resistance protein (MDR1) in drug-mediated control of ATP hydrolysis.
Szakács G, Ozvegy C, Bakos E, Sarkadi B, Váradi A. Szakács G, et al. Biochem J. 2001 May 15;356(Pt 1):71-5. doi: 10.1042/0264-6021:3560071. Biochem J. 2001. PMID: 11336637 Free PMC article.
Functional characterization of the human multidrug transporter, ABCG2, expressed in insect cells.
Ozvegy C, Litman T, Szakács G, Nagy Z, Bates S, Váradi A, Sarkadi B. Ozvegy C, et al. Among authors: szakacs g. Biochem Biophys Res Commun. 2001 Jul 6;285(1):111-7. doi: 10.1006/bbrc.2001.5130. Biochem Biophys Res Commun. 2001. PMID: 11437380
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