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Frequent long-range epigenetic silencing of protocadherin gene clusters on chromosome 5q31 in Wilms' tumor.
Dallosso AR, Hancock AL, Szemes M, Moorwood K, Chilukamarri L, Tsai HH, Sarkar A, Barasch J, Vuononvirta R, Jones C, Pritchard-Jones K, Royer-Pokora B, Lee SB, Owen C, Malik S, Feng Y, Frank M, Ward A, Brown KW, Malik K. Dallosso AR, et al. Among authors: szemes m. PLoS Genet. 2009 Nov;5(11):e1000745. doi: 10.1371/journal.pgen.1000745. Epub 2009 Nov 26. PLoS Genet. 2009. PMID: 19956686 Free PMC article.
Long-range epigenetic silencing of chromosome 5q31 protocadherins is involved in early and late stages of colorectal tumorigenesis through modulation of oncogenic pathways.
Dallosso AR, Øster B, Greenhough A, Thorsen K, Curry TJ, Owen C, Hancock AL, Szemes M, Paraskeva C, Frank M, Andersen CL, Malik K. Dallosso AR, et al. Among authors: szemes m. Oncogene. 2012 Oct 4;31(40):4409-19. doi: 10.1038/onc.2011.609. Epub 2012 Jan 16. Oncogene. 2012. PMID: 22249255 Free PMC article.
The epithelial splicing regulator ESRP2 is epigenetically repressed by DNA hypermethylation in Wilms tumour and acts as a tumour suppressor.
Legge D, Li L, Moriarty W, Lee D, Szemes M, Zahed A, Panousopoulos L, Chung WY, Aghabi Y, Barratt J, Williams R, Pritchard-Jones K, Malik KTA, Oltean S, Brown KW. Legge D, et al. Among authors: szemes m. Mol Oncol. 2022 Feb;16(3):630-647. doi: 10.1002/1878-0261.13101. Epub 2021 Sep 28. Mol Oncol. 2022. PMID: 34520622 Free PMC article.
31 results