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The impact of genetic markers on the diagnosis of lung cancer: a current perspective.
Chorostowska-Wynimko J, Szpechcinski A. Chorostowska-Wynimko J, et al. J Thorac Oncol. 2007 Nov;2(11):1044-51. doi: 10.1097/JTO.0b013e318158eed4. J Thorac Oncol. 2007. PMID: 17975498 Review.
Reliable detection of rare mutations in EGFR gene codon L858 by PNA-LNA PCR clamp in non-small cell lung cancer.
Skronski M, Chorostowska-Wynimko J, Szczepulska E, Szpechcinski A, Rudzinski P, Orlowski T, Langfort R. Skronski M, et al. Among authors: szpechcinski a. Adv Exp Med Biol. 2013;756:321-31. doi: 10.1007/978-94-007-4549-0_39. Adv Exp Med Biol. 2013. PMID: 22836650
Plasma cell-free DNA levels and integrity in patients with chest radiological findings: NSCLC versus benign lung nodules.
Szpechcinski A, Rudzinski P, Kupis W, Langfort R, Orlowski T, Chorostowska-Wynimko J. Szpechcinski A, et al. Cancer Lett. 2016 May 1;374(2):202-7. doi: 10.1016/j.canlet.2016.02.002. Epub 2016 Feb 5. Cancer Lett. 2016. PMID: 26854716
[Highlights from the ERS Congress in Amsterdam, 24-28 September, 2011].
Kuca P, Puścińska E, Szpechciński A, Chorostowska-Wynimko J, Szturmowicz M. Kuca P, et al. Pneumonol Alergol Pol. 2012;80(3):280-6. Pneumonol Alergol Pol. 2012. PMID: 22562279 Polish. No abstract available.
Quantitative analysis of free-circulating DNA in plasma of patients with resectable NSCLC.
Szpechcinski A, Chorostowska-Wynimko J, Kupis W, Maszkowska-Kopij K, Dancewicz M, Kowalewski J, Orlowski T. Szpechcinski A, et al. Expert Opin Biol Ther. 2012 Jun;12 Suppl 1:S3-9. doi: 10.1517/14712598.2012.668519. Epub 2012 May 5. Expert Opin Biol Ther. 2012. PMID: 22559166

Drastic increase in plasma DNA levels up to mean 68.74 ng/ml was detected a week after primary tumor resection. Still, similar phenomenon was observed in patients subjected to orthopedic surgical treatment (from 3.00 to 28.38 ng/ml, p < 0.0015). ...Importantly, the kine

Drastic increase in plasma DNA levels up to mean 68.74 ng/ml was detected a week after primary tumor resection. Still, similar phenom …
[Molecular diagnostics of alpha-1-antitrypsin deficiency in clinical practice].
Struniawski R, Szpechciński A, Chorostowska-Wynimko J. Struniawski R, et al. Pneumonol Alergol Pol. 2008;76(4):253-64. Pneumonol Alergol Pol. 2008. PMID: 18785130 Review. Polish.
Cell-free DNA levels in plasma of patients with non-small-cell lung cancer and inflammatory lung disease.
Szpechcinski A, Chorostowska-Wynimko J, Struniawski R, Kupis W, Rudzinski P, Langfort R, Puscinska E, Bielen P, Sliwinski P, Orlowski T. Szpechcinski A, et al. Br J Cancer. 2015 Jul 28;113(3):476-83. doi: 10.1038/bjc.2015.225. Epub 2015 Jun 30. Br J Cancer. 2015. PMID: 26125447 Free PMC article.
Rapid DNA extraction protocol for detection of alpha-1 antitrypsin deficiency from dried blood spots by real-time PCR.
Struniawski R, Szpechcinski A, Poplawska B, Skronski M, Chorostowska-Wynimko J. Struniawski R, et al. Adv Exp Med Biol. 2013;756:29-37. doi: 10.1007/978-94-007-4549-0_5. Adv Exp Med Biol. 2013. PMID: 22836616
In the present study we propose a fast, efficient, and cost effective protocol of DNA extraction from dried blood spot (DBS) samples that provides sufficient quantity and quality of DNA and effectively eliminates any natural PCR inhibitors, allowing for successful AAT geno …
In the present study we propose a fast, efficient, and cost effective protocol of DNA extraction from dried blood spot (DBS) samples …
Real-time PCR quantification of plasma DNA in non-small cell lung cancer patients and healthy controls.
Szpechcinski A, Dancewicz M, Kopinski P, Kowalewski J, Chorostowska-Wynimko J. Szpechcinski A, et al. Eur J Med Res. 2009 Dec 7;14 Suppl 4(Suppl 4):237-40. doi: 10.1186/2047-783x-14-s4-237. Eur J Med Res. 2009. PMID: 20156763 Free PMC article.
INTRODUCTION: Free-circulating DNA is present in minute amounts in plasma of healthy individuals, whereas increased levels are found in a number of malignant pathologies including non-small cell lung cancer (NSCLC). ...A greater variability of plasma DNA concentrati …
INTRODUCTION: Free-circulating DNA is present in minute amounts in plasma of healthy individuals, whereas increased levels are found in a
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