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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1799 3
1807 2
1814 1
1816 1
1827 1
1838 3
1840 1
1842 1
1845 3
1846 6
1847 5
1848 4
1849 6
1850 2
1853 1
1854 3
1855 4
1856 3
1857 2
1858 1
1860 3
1861 2
1862 2
1863 4
1864 3
1865 4
1866 8
1867 9
1868 4
1869 3
1870 4
1871 1
1872 5
1873 6
1874 3
1875 8
1876 3
1877 3
1878 1
1879 6
1880 1
1881 7
1882 1
1883 6
1884 6
1885 6
1886 12
1887 11
1888 13
1889 8
1890 8
1891 6
1892 8
1893 3
1894 1
1895 4
1896 5
1897 7
1898 9
1899 2
1900 9
1901 4
1902 16
1903 4
1905 2
1906 3
1907 3
1908 5
1909 3
1910 4
1911 5
1912 1
1913 10
1914 3
1915 11
1916 10
1917 19
1918 18
1919 15
1920 9
1921 3
1922 6
1923 3
1924 10
1925 18
1926 16
1927 14
1928 11
1929 12
1930 13
1931 12
1932 14
1933 13
1934 15
1935 10
1936 8
1937 5
1938 14
1939 14
1940 13
1941 19
1942 16
1943 16
1944 20
1945 48
1946 126
1947 135
1948 131
1949 118
1950 238
1951 377
1952 381
1953 381
1954 349
1955 271
1956 276
1957 270
1958 254
1959 207
1960 198
1961 207
1962 221
1963 650
1964 920
1965 594
1966 652
1967 595
1968 616
1969 633
1970 854
1971 1015
1972 1363
1973 2136
1974 4126
1975 34068
1976 35604
1977 36954
1978 38028
1979 40650
1980 58481
1981 79334
1982 84699
1983 92743
1984 96944
1985 100073
1986 106269
1987 112245
1988 118057
1989 125431
1990 130840
1991 136145
1992 142321
1993 147315
1994 155857
1995 161760
1996 166764
1997 173788
1998 182705
1999 192680
2000 208709
2001 219854
2002 231736
2003 251682
2004 277004
2005 301366
2006 306514
2007 330569
2008 357613
2009 384386
2010 421935
2011 462247
2012 500517
2013 531514
2014 553123
2015 558426
2016 372230
2017 272400
2018 393088
2019 409710
2020 448417
2021 475072
2022 452295
2023 378382
2024 176962
2025 1096
2026 3

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10,966,478 results

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The following terms were ignored: %, %, %, %, %, %, %
The following terms were not found in PubMed: 252525C3, 252525B6r, 252525C3, 252525BCner, 25252520M, 2525255BAuthor, 2525255D
Page 1
CD8(+) T cell exhaustion.
Kurachi M. Kurachi M. Semin Immunopathol. 2019 May;41(3):327-337. doi: 10.1007/s00281-019-00744-5. Epub 2019 Apr 15. Semin Immunopathol. 2019. PMID: 30989321 Review.
In the case of chronic infection or cancer, CD8(+) T cells are exposed to persistent antigen and/or inflammatory signals. This excessive amount of signals often leads CD8(+) T cells to gradual deterioration of T cell function, a state called "exhaustion." ... …
In the case of chronic infection or cancer, CD8(+) T cells are exposed to persistent antigen and/or inflammatory signals. This excess …
Heterogeneity in the differentiation and function of CD8+ T cells.
Mittrücker HW, Visekruna A, Huber M. Mittrücker HW, et al. Arch Immunol Ther Exp (Warsz). 2014 Dec;62(6):449-58. doi: 10.1007/s00005-014-0293-y. Epub 2014 May 31. Arch Immunol Ther Exp (Warsz). 2014. PMID: 24879097 Free article. Review.
However, there is growing evidence for alternative CD8(+) T cell fates influencing CD4(+) T-cell-mediated responses in the context of allergy, autoimmunity and infections. ...These environmental cues induce transcription factors further specifying CD8(+) T-ce …
However, there is growing evidence for alternative CD8(+) T cell fates influencing CD4(+) T-cell-mediated responses in the con …
Anti-ergotypic immunoregulation.
Quintana FJ, Cohen IR. Quintana FJ, et al. Scand J Immunol. 2006 Sep;64(3):205-10. doi: 10.1111/j.1365-3083.2006.01807.x. Scand J Immunol. 2006. PMID: 16918688 Free article. Review.
T-cell vaccination (TCV) controls pathogenic autoimmune T-cell responses via two different regulatory cell populations: anti-idiotypic and anti-ergotypic T cells. Anti-idiotypic T cells recognize clone-specific determinants, like the CDR3 region of the …
T-cell vaccination (TCV) controls pathogenic autoimmune T-cell responses via two different regulatory cell populations: anti-i …
Stability and function of regulatory T cells expressing the transcription factor T-bet.
Levine AG, Mendoza A, Hemmers S, Moltedo B, Niec RE, Schizas M, Hoyos BE, Putintseva EV, Chaudhry A, Dikiy S, Fujisawa S, Chudakov DM, Treuting PM, Rudensky AY. Levine AG, et al. Nature. 2017 Jun 15;546(7658):421-425. doi: 10.1038/nature22360. Epub 2017 Jun 7. Nature. 2017. PMID: 28607488 Free PMC article.
Loss of function or elimination of T-bet-expressing T(reg) cells-but not of T-bet expression in T(reg) cells-resulted in severe T(H)1 autoimmunity. Conversely, following depletion of T-bet(-) T(reg) cells, the remaining T-be …
Loss of function or elimination of T-bet-expressing T(reg) cells-but not of T-bet expression in T(reg) cells-res …
Artificial Methods for T Cell Activation: Critical Tools in T Cell Biology and T Cell Immunotherapy.
Roh KH. Roh KH. Adv Exp Med Biol. 2018;1064:207-219. doi: 10.1007/978-981-13-0445-3_13. Adv Exp Med Biol. 2018. PMID: 30471035 Review.
A variety of biomimetic approaches have been devised to artificially induce T cell activation either to study the T cell biology or to expand and prime the therapeutic T cell populations. ...With the growing number of successful adoptive T cell therapi …
A variety of biomimetic approaches have been devised to artificially induce T cell activation either to study the T cell biolo …
[Characteristics of T lymphocyte subpopulations].
Niedźwiedzka-Rystwej P, Tokarz-Deptuła B, Deptuła W. Niedźwiedzka-Rystwej P, et al. Postepy Hig Med Dosw (Online). 2013 May 10;67:371-9. doi: 10.5604/17322693.1048814. Postepy Hig Med Dosw (Online). 2013. PMID: 23667096 Free article. Review. Polish.
The paper describes the characteristics, receptor profile and functions of T lymphocyte subpopulations (helper, cytotoxic, regulatory, memory and others). Among T helper cells one can enumerate Th0, Th1, Th2, Th9, Th17, Th22, T(FH) and nTh2, while T cy …
The paper describes the characteristics, receptor profile and functions of T lymphocyte subpopulations (helper, cytotoxic, regulatory …
CD8+ regulatory T cells-A distinct T-cell lineage or a transient T-cell phenotype?
Aandahl EM, Torgersen KM, Taskén K. Aandahl EM, et al. Hum Immunol. 2008 Nov;69(11):696-9. doi: 10.1016/j.humimm.2008.08.291. Epub 2008 Sep 24. Hum Immunol. 2008. PMID: 18817824 Review.
Both the CD4(+) and the CD8(+) T cell compartments contain regulatory T cells. Although various CD4(+) regulatory T-cell subsets represent the best characterized regulatory T-cell populations, CD8(+) regulatory T cells also have strong immunosup …
Both the CD4(+) and the CD8(+) T cell compartments contain regulatory T cells. Although various CD4(+) regulatory T-cel …
T Cell-Associated Immunotherapy for Hepatocellular Carcinoma.
Ma W, Wu L, Zhou F, Hong Z, Yuan Y, Liu Z. Ma W, et al. Cell Physiol Biochem. 2017;41(2):609-622. doi: 10.1159/000457883. Epub 2017 Feb 3. Cell Physiol Biochem. 2017. PMID: 28214839 Free article. Review.
Accumulating evidences suggest that immunotherapy could be a promising option for treating HCC. T cell-associated immunotherapy lights up the hope for the improvement of complementary approach to conventional HCC treatments, which needs further research to consummate the c …
Accumulating evidences suggest that immunotherapy could be a promising option for treating HCC. T cell-associated immunotherapy light …
The role of T cell receptor dimerization for T cell antagonism and T cell specificity.
Salzmann M, Bachmann MF. Salzmann M, et al. Mol Immunol. 1998 Apr;35(5):271-7. doi: 10.1016/s0161-5890(98)00035-2. Mol Immunol. 1998. PMID: 9747887 Review.
T cell responses are highly specific and T cell receptors (TCRs) can recognise subtle differences in major histocompatibility complex (MHC)-peptide complexes. ...The present study analyses mathematically the role of TCR-dimerization for T cell antagonism and …
T cell responses are highly specific and T cell receptors (TCRs) can recognise subtle differences in major histocompatibility …
Cytotoxic CD8+ Lymphocytes in the Tumor Microenvironment.
Iwahori K. Iwahori K. Adv Exp Med Biol. 2020;1224:53-62. doi: 10.1007/978-3-030-35723-8_4. Adv Exp Med Biol. 2020. PMID: 32036604 Review.
In the tumor microenvironment, CD8(+) T cells play a major role in tumor immunity. CD8(+) T cells differentiate to cytotoxic T cells, traffic into the tumor microenvironment, and exhibit cytotoxicity against tumor cells. ...To achieve this, several immunother …
In the tumor microenvironment, CD8(+) T cells play a major role in tumor immunity. CD8(+) T cells differentiate to cytotoxic …
10,966,478 results
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