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Premature ageing in mice expressing defective mitochondrial DNA polymerase.
Trifunovic A, Wredenberg A, Falkenberg M, Spelbrink JN, Rovio AT, Bruder CE, Bohlooly-Y M, Gidlöf S, Oldfors A, Wibom R, Törnell J, Jacobs HT, Larsson NG. Trifunovic A, et al. Nature. 2004 May 27;429(6990):417-23. doi: 10.1038/nature02517. Nature. 2004. PMID: 15164064
G protein-coupled receptor 12 deficiency results in dyslipidemia and obesity in mice.
Bjursell M, Gerdin AK, Jönsson M, Surve VV, Svensson L, Huang XF, Törnell J, Bohlooly-Y M. Bjursell M, et al. Among authors: tornell j. Biochem Biophys Res Commun. 2006 Sep 22;348(2):359-66. doi: 10.1016/j.bbrc.2006.07.090. Epub 2006 Jul 28. Biochem Biophys Res Commun. 2006. PMID: 16887097
GH substitution reverses the growth phenotype but not the defective ossification in thyroid hormone receptor alpha 1-/-beta-/- mice.
Kindblom JM, Göthe S, Forrest D, Törnell J, Törnell J, Vennström B, Ohlsson C. Kindblom JM, et al. J Endocrinol. 2001 Oct;171(1):15-22. doi: 10.1677/joe.0.1710015. J Endocrinol. 2001. PMID: 11572786
Liver-derived insulin-like growth factor I (IGF-I) is the principal source of IGF-I in blood but is not required for postnatal body growth in mice.
Sjögren K, Liu JL, Blad K, Skrtic S, Vidal O, Wallenius V, LeRoith D, Törnell J, Isaksson OG, Jansson JO, Ohlsson C. Sjögren K, et al. Proc Natl Acad Sci U S A. 1999 Jun 8;96(12):7088-92. doi: 10.1073/pnas.96.12.7088. Proc Natl Acad Sci U S A. 1999. PMID: 10359843 Free PMC article.
Phenotypic screening of hepatocyte nuclear factor (HNF) 4-gamma receptor knockout mice.
Gerdin AK, Surve VV, Jönsson M, Bjursell M, Björkman M, Edenro A, Schuelke M, Saad A, Bjurström S, Lundgren EJ, Snaith M, Fransson-Steen R, Törnell J, Berg AL, Bohlooly-Y M. Gerdin AK, et al. Among authors: tornell j. Biochem Biophys Res Commun. 2006 Oct 20;349(2):825-32. doi: 10.1016/j.bbrc.2006.08.103. Epub 2006 Aug 24. Biochem Biophys Res Commun. 2006. PMID: 16945327
Melanin-concentrating hormone receptor 1 deficiency increases insulin sensitivity in obese leptin-deficient mice without affecting body weight.
Bjursell M, Gerdin AK, Ploj K, Svensson D, Svensson L, Oscarsson J, Snaith M, Törnell J, Bohlooly-Y M. Bjursell M, et al. Among authors: tornell j. Diabetes. 2006 Mar;55(3):725-33. doi: 10.2337/diabetes.55.03.06.db05-1302. Diabetes. 2006. PMID: 16505236 Free article.
Importance of melanin-concentrating hormone receptor for the acute effects of ghrelin.
Bjursell M, Egecioglu E, Gerdin AK, Svensson L, Oscarsson J, Morgan D, Snaith M, Törnell J, Bohlooly-Y M. Bjursell M, et al. Biochem Biophys Res Commun. 2005 Jan 28;326(4):759-65. doi: 10.1016/j.bbrc.2004.11.116. Biochem Biophys Res Commun. 2005. PMID: 15607734
Growth hormone overexpression in the central nervous system results in hyperphagia-induced obesity associated with insulin resistance and dyslipidemia.
Bohlooly-Y M, Olsson B, Bruder CE, Lindén D, Sjögren K, Bjursell M, Egecioglu E, Svensson L, Brodin P, Waterton JC, Isaksson OG, Sundler F, Ahrén B, Ohlsson C, Oscarsson J, Törnell J. Bohlooly-Y M, et al. Diabetes. 2005 Jan;54(1):51-62. doi: 10.2337/diabetes.54.1.51. Diabetes. 2005. PMID: 15616010
Bovine growth hormone transgenic mice are resistant to diet-induced obesity but develop hyperphagia, dyslipidemia, and diabetes on a high-fat diet.
Olsson B, Bohlooly-Y M, Fitzgerald SM, Frick F, Ljungberg A, Ahrén B, Törnell J, Bergström G, Oscarsson J. Olsson B, et al. Endocrinology. 2005 Feb;146(2):920-30. doi: 10.1210/en.2004-1232. Epub 2004 Nov 11. Endocrinology. 2005. PMID: 15539551
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