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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1953 1
1962 2
1963 2
1966 1
1968 1
1969 1
1971 2
1973 1
1974 6
1975 29
1976 27
1977 25
1978 25
1979 36
1980 57
1981 104
1982 110
1983 124
1984 155
1985 124
1986 158
1987 147
1988 192
1989 227
1990 244
1991 246
1992 241
1993 251
1994 300
1995 318
1996 371
1997 358
1998 440
1999 436
2000 492
2001 461
2002 453
2003 469
2004 524
2005 579
2006 524
2007 672
2008 699
2009 697
2010 777
2011 850
2012 895
2013 935
2014 892
2015 904
2016 568
2017 464
2018 650
2019 646
2020 692
2021 825
2022 729
2023 612
2024 335
2025 2

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19,241 results

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Page 1
Molecular markers in ALL: Clinical implications.
Kimura S, Mullighan CG. Kimura S, et al. Best Pract Res Clin Haematol. 2020 Sep;33(3):101193. doi: 10.1016/j.beha.2020.101193. Epub 2020 Jun 7. Best Pract Res Clin Haematol. 2020. PMID: 33038982 Free PMC article. Review.
In the past decade, development of massively parallel sequencing has enabled large scale genome profiling studies of ALL, which not only led to identification of new subtypes in both B-cell precursor ALL (BCP-ALL) and T-cell ALL (T-ALL), but has also identified pote …
In the past decade, development of massively parallel sequencing has enabled large scale genome profiling studies of ALL, which not only led …
IL-6: regulator of Treg/Th17 balance.
Kimura A, Kishimoto T. Kimura A, et al. Eur J Immunol. 2010 Jul;40(7):1830-5. doi: 10.1002/eji.201040391. Eur J Immunol. 2010. PMID: 20583029 Free article. Review.
Recent studies have demonstrated that IL-6 has a very important role in regulating the balance between IL-17-producing Th17 cells and regulatory T cells (Treg). The two T-cell subsets play prominent roles in immune functions: Th17 cell is a key player in the pathoge …
Recent studies have demonstrated that IL-6 has a very important role in regulating the balance between IL-17-producing Th17 cells and regula …
IL7 increases targeted lipid nanoparticle-mediated mRNA expression in T cells in vitro and in vivo by enhancing T cell protein translation.
Tilsed CM, Sadiq BA, Papp TE, Areesawangkit P, Kimura K, Noguera-Ortega E, Scholler J, Cerda N, Aghajanian H, Bot A, Mui B, Tam Y, Weissman D, June CH, Albelda SM, Parhiz H. Tilsed CM, et al. Among authors: kimura k. Proc Natl Acad Sci U S A. 2024 Mar 26;121(13):e2319856121. doi: 10.1073/pnas.2319856121. Epub 2024 Mar 21. Proc Natl Acad Sci U S A. 2024. PMID: 38513098 Free PMC article.
T cell health and activation can be increased with cytokines, therefore, using mCherry mRNA as a reporter, we found that culturing either mouse or human T cells with the cytokine IL7 significantly improved protein expression of delivered mRNA in both CD4(+) and CD8( …
T cell health and activation can be increased with cytokines, therefore, using mCherry mRNA as a reporter, we found that culturing ei …
EBV in T-/NK-Cell Tumorigenesis.
Kimura H. Kimura H. Adv Exp Med Biol. 2018;1045:459-475. doi: 10.1007/978-981-10-7230-7_21. Adv Exp Med Biol. 2018. PMID: 29896680 Review.
Epstein-Barr virus (EBV), which is associated with B-cell proliferative disorders, also transforms T- or natural killer (NK)-lineage cells and has been connected with various T- or NK (T/NK)-cell malignancies, such as extranodal NK/T-cell lymphoma-nasa …
Epstein-Barr virus (EBV), which is associated with B-cell proliferative disorders, also transforms T- or natural killer (NK)-lineage …
Overview of EBV-Associated T/NK-Cell Lymphoproliferative Diseases.
Kimura H, Fujiwara S. Kimura H, et al. Front Pediatr. 2019 Jan 4;6:417. doi: 10.3389/fped.2018.00417. eCollection 2018. Front Pediatr. 2019. PMID: 30662890 Free PMC article. Review.
Epstein-Barr virus-associated T/natural killer-cell lymphoproliferative diseases (EBV-T/NK-LPDs) are a group of rare diseases resulting from ectopic infection of T or natural killer (NK) lymphocytes with Epstein-Barr virus (EBV). ...Extra-nodal NK/T-ce …
Epstein-Barr virus-associated T/natural killer-cell lymphoproliferative diseases (EBV-T/NK-LPDs) are a group of rare diseases …
T cell immunity in interstitial lung disease with non-small cell lung cancer patients.
Isono T, Iwahori K, Yanagawa M, Yamamoto Y, Tone M, Haruna M, Hirata M, Fukui E, Kimura T, Kanou T, Ose N, Funaki S, Takeda Y, Morii E, Kumanogoh A, Shintani Y, Wada H. Isono T, et al. Among authors: kimura t. Lung Cancer. 2023 Aug;182:107278. doi: 10.1016/j.lungcan.2023.107278. Epub 2023 Jun 9. Lung Cancer. 2023. PMID: 37321075
T cell functions were measured based on cytokine production by T cells stimulated with phorbol 12-myristate 13-acetate and ionomycin. RESULTS: The percentages of CD4(+) T cells expressing immune checkpoint molecules (Tim-3, ICOS, and 4-1BB), CD103(+)CD8(+) …
T cell functions were measured based on cytokine production by T cells stimulated with phorbol 12-myristate 13-acetate and ion …
Cancer therapeutic trispecific antibodies recruiting both T and natural killer cells to cancer cells.
Kimura K, Kuwahara A, Suzuki S, Nakanishi T, Kumagai I, Asano R. Kimura K, et al. Oncol Rep. 2023 Dec;50(6):212. doi: 10.3892/or.2023.8649. Epub 2023 Oct 20. Oncol Rep. 2023. PMID: 37859608 Free PMC article.
In the present study, trispecific antibodies were created, namely T cell and NK cell engagers (TaKEs), that recruit both T cells and NK cells. Notably, three Fc-fused TaKEs were designed, TaKE1-Fc, TaKE2-Fc and TaKE3-Fc, using variable fragments targeting the epider …
In the present study, trispecific antibodies were created, namely T cell and NK cell engagers (TaKEs), that recruit both T cel …
Antitumor activity of alpha-pinene in T-cell tumors.
Abe M, Asada N, Kimura M, Fukui C, Yamada D, Wang Z, Miyake M, Takarada T, Ono M, Aoe M, Kitamura W, Matsuda M, Moriyama T, Matsumura A, Maeda Y. Abe M, et al. Among authors: kimura m. Cancer Sci. 2024 Apr;115(4):1317-1332. doi: 10.1111/cas.16086. Epub 2024 Jan 26. Cancer Sci. 2024. PMID: 38279512 Free PMC article.
This report provides a comprehensive analysis of the potential benefits of using alpha-pinene as an antitumor agent for the treatment of T-cell tumors. We found that alpha-pinene inhibited the proliferation of hematologic malignancies, especially in T-cell tumor cel …
This report provides a comprehensive analysis of the potential benefits of using alpha-pinene as an antitumor agent for the treatment of …
Th17 cells in inflammation.
Kimura A, Kishimoto T. Kimura A, et al. Int Immunopharmacol. 2011 Mar;11(3):319-22. doi: 10.1016/j.intimp.2010.10.004. Epub 2010 Oct 28. Int Immunopharmacol. 2011. PMID: 21035432 Review.
Naive T cells are multipotential precursors that differentiate into various effector subsets, such as T helper type 1 (Th1) and Th2 cells, which are characterized by their distinct functions. The IL-17-producing T helper (Th17) cell has been recently identifi …
Naive T cells are multipotential precursors that differentiate into various effector subsets, such as T helper type 1 (Th1) an …
CD69 Imposes Tumor-Specific CD8+ T-cell Fate in Tumor-Draining Lymph Nodes.
Koyama-Nasu R, Kimura MY, Kiuchi M, Aoki A, Wang Y, Mita Y, Hasegawa I, Endo Y, Onodera A, Hirahara K, Motohashi S, Nakayama T. Koyama-Nasu R, et al. Among authors: kimura my. Cancer Immunol Res. 2023 Aug 3;11(8):1085-1099. doi: 10.1158/2326-6066.CIR-22-0406. Cancer Immunol Res. 2023. PMID: 37216576
Intratumoral CD8+ T cells are heterogeneous; Tcf1+ stemlike CD8+ T cells give rise to their cytotoxic progeny-Tim-3+ terminally differentiated CD8+ T cells. ...In TDLNs, CD69 deficiency diminished TOX expression in tumor-specific CD8+ T cells, and cons …
Intratumoral CD8+ T cells are heterogeneous; Tcf1+ stemlike CD8+ T cells give rise to their cytotoxic progeny-Tim-3+ terminall …
19,241 results
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