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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1970 1
1973 1
1975 3
1976 6
1977 4
1978 6
1979 7
1980 20
1981 24
1982 38
1983 45
1984 37
1985 43
1986 68
1987 84
1988 97
1989 92
1990 105
1991 61
1992 97
1993 103
1994 114
1995 131
1996 122
1997 124
1998 153
1999 186
2000 249
2001 198
2002 202
2003 281
2004 244
2005 258
2006 260
2007 285
2008 246
2009 269
2010 312
2011 329
2012 381
2013 396
2014 378
2015 419
2016 277
2017 221
2018 297
2019 290
2020 323
2021 337
2022 298
2023 260
2024 23

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7,974 results

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Page 1
Anti-GPRC5D/CD3 Bispecific T-Cell-Redirecting Antibody for the Treatment of Multiple Myeloma.
Kodama T, Kochi Y, Nakai W, Mizuno H, Baba T, Habu K, Sawada N, Tsunoda H, Shima T, Miyawaki K, Kikushige Y, Mori Y, Miyamoto T, Maeda T, Akashi K. Kodama T, et al. Among authors: miyamoto t. Mol Cancer Ther. 2019 Sep;18(9):1555-1564. doi: 10.1158/1535-7163.MCT-18-1216. Epub 2019 Jul 3. Mol Cancer Ther. 2019. PMID: 31270154
In addition, we constructed IgG-based anti-GPRC5D/CD3 bispecific T-cell-redirecting antibodies (GPRC5D TRAB), which suppressed the tumor growth of GPRC5D-positive myeloma cells through the activation of T cells in vitro and in vivo in xenograft models. ...
In addition, we constructed IgG-based anti-GPRC5D/CD3 bispecific T-cell-redirecting antibodies (GPRC5D TRAB), which suppressed the tu …
Illuminating Stannylation.
Sakamoto K, Nagashima Y, Wang C, Miyamoto K, Tanaka K, Uchiyama M. Sakamoto K, et al. Among authors: miyamoto k. J Am Chem Soc. 2021 Apr 21;143(15):5629-5635. doi: 10.1021/jacs.1c00887. Epub 2021 Mar 26. J Am Chem Soc. 2021. PMID: 33769051
We have developed photoboosted stannylation reactions of terminal alkynes (linear-selective hydrostannylation) and fluoroarenes (defluorostannylation), in which the stannyl anion is photoexcited to an excited triplet (T(1)) stannyl diradical species. This unprecedented …
We have developed photoboosted stannylation reactions of terminal alkynes (linear-selective hydrostannylation) and fluoroarenes (defluorosta …
The liver-brain-gut neural arc maintains the T(reg) cell niche in the gut.
Teratani T, Mikami Y, Nakamoto N, Suzuki T, Harada Y, Okabayashi K, Hagihara Y, Taniki N, Kohno K, Shibata S, Miyamoto K, Ishigame H, Chu PS, Sujino T, Suda W, Hattori M, Matsui M, Okada T, Okano H, Inoue M, Yada T, Kitagawa Y, Yoshimura A, Tanida M, Tsuda M, Iwasaki Y, Kanai T. Teratani T, et al. Among authors: miyamoto k. Nature. 2020 Sep;585(7826):591-596. doi: 10.1038/s41586-020-2425-3. Epub 2020 Jun 11. Nature. 2020. PMID: 32526765
Despite recent advances in our understanding of neuroimmune interactions, it remains unclear how the gut and brain communicate to maintain gut immune homeostasis, including in the induction and maintenance of peripheral regulatory T cells (pT(reg) cells), and what environm …
Despite recent advances in our understanding of neuroimmune interactions, it remains unclear how the gut and brain communicate to maintain g …
Gut pathobionts underlie intestinal barrier dysfunction and liver T helper 17 cell immune response in primary sclerosing cholangitis.
Nakamoto N, Sasaki N, Aoki R, Miyamoto K, Suda W, Teratani T, Suzuki T, Koda Y, Chu PS, Taniki N, Yamaguchi A, Kanamori M, Kamada N, Hattori M, Ashida H, Sakamoto M, Atarashi K, Narushima S, Yoshimura A, Honda K, Sato T, Kanai T. Nakamoto N, et al. Among authors: miyamoto k. Nat Microbiol. 2019 Mar;4(3):492-503. doi: 10.1038/s41564-018-0333-1. Epub 2019 Jan 14. Nat Microbiol. 2019. PMID: 30643240
Gnotobiotic mice inoculated with PSC-derived microbiota exhibited T helper 17 (T(H)17) cell responses in the liver and increased susceptibility to hepatobiliary injuries. ...A bacterial-organoid co-culture system visualized the epithelial-damaging effect of PSC-deri …
Gnotobiotic mice inoculated with PSC-derived microbiota exhibited T helper 17 (T(H)17) cell responses in the liver and increas …
B7-H3 Suppresses Antitumor Immunity via the CCL2-CCR2-M2 Macrophage Axis and Contributes to Ovarian Cancer Progression.
Miyamoto T, Murakami R, Hamanishi J, Tanigaki K, Hosoe Y, Mise N, Takamatsu S, Mise Y, Ukita M, Taki M, Yamanoi K, Horikawa N, Abiko K, Yamaguchi K, Baba T, Matsumura N, Mandai M. Miyamoto T, et al. Cancer Immunol Res. 2022 Jan;10(1):56-69. doi: 10.1158/2326-6066.CIR-21-0407. Epub 2021 Nov 19. Cancer Immunol Res. 2022. PMID: 34799346 Free PMC article.
In syngeneic mouse models, B7-H3 (Cd276) knockout (KO) in tumor cells, but not in stromal cells, suppressed tumor progression, with a reduced number of M2 macrophages and an increased number of IFNgamma(+)CD8(+) T cells. CCL2 expression was downregulated in the B7-H3 KO tu …
In syngeneic mouse models, B7-H3 (Cd276) knockout (KO) in tumor cells, but not in stromal cells, suppressed tumor progression, with a reduce …
Peripheral helper-T-cell-derived CXCL13 is a crucial pathogenic factor in idiopathic multicentric Castleman disease.
Harada T, Kikushige Y, Miyamoto T, Uno K, Niiro H, Kawakami A, Koga T, Akashi K, Yoshizaki K. Harada T, et al. Among authors: miyamoto t. Nat Commun. 2023 Oct 31;14(1):6959. doi: 10.1038/s41467-023-42718-0. Nat Commun. 2023. PMID: 37907518 Free PMC article.
Immunodeficient mice, transplanted with lymph node (LN) cells from iMCD-NOS patients, develop iMCD-like lethal inflammation, while mice transplanted with LN cells from non-iMCD patients without inflammation serve as negative control. Grafts depleted of human CD3(+) T cells …
Immunodeficient mice, transplanted with lymph node (LN) cells from iMCD-NOS patients, develop iMCD-like lethal inflammation, while mice tran …
Single-cell transcriptomics of human gut T cells identifies cytotoxic CD4(+)CD8A(+) T cells related to mouse CD4 cytotoxic T cells.
Tanemoto S, Sujino T, Miyamoto K, Moody J, Yoshimatsu Y, Ando Y, Koya I, Harada Y, Tojo AO, Ono K, Hayashi Y, Takabayashi K, Okabayashi K, Teratani T, Mikami Y, Nakamoto N, Hosoe N, Ogata H, Hon CC, Shin JW, Kanai T. Tanemoto S, et al. Among authors: miyamoto k. Front Immunol. 2022 Oct 24;13:977117. doi: 10.3389/fimmu.2022.977117. eCollection 2022. Front Immunol. 2022. PMID: 36353619 Free PMC article.
The population of cytotoxic CD4(+) T cells in the human intestine is currently unknown. Moreover, it is unclear how cytotoxic CD4 T cells change in patients with inflammatory bowel disease (IBD). ...In CD4(+) T cells, granzyme and perforin expression was high …
The population of cytotoxic CD4(+) T cells in the human intestine is currently unknown. Moreover, it is unclear how cytotoxic CD4 …
Establishing a whole blood CD4(+) T cell immunity measurement to predict response to anti-PD-1.
Yamaguchi O, Atarashi K, Yoshimura K, Shiono A, Mouri A, Nishihara F, Miura Y, Hashimoto K, Miyamoto Y, Uga H, Seki N, Matsushima T, Kikukawa N, Kobayashi K, Kaira K, Kagamu H. Yamaguchi O, et al. Among authors: miyamoto y. BMC Cancer. 2022 Dec 17;22(1):1325. doi: 10.1186/s12885-022-10445-2. BMC Cancer. 2022. PMID: 36528575 Free PMC article.
We have previously reported a novel formula that predicts the response to treatment with second-line nivolumab with high sensitivity and specificity in patients with non-small cell lung cancer (NSCLC) previously treated with chemotherapy. The formula was based on the percentages …
We have previously reported a novel formula that predicts the response to treatment with second-line nivolumab with high sensitivity and spe …
Diverse roles of integrins in human T lymphocyte biology.
Miyamoto Y, Andruss B, Mitchell J, Billard M, McIntyre B. Miyamoto Y, et al. Immunol Res. 2003;27(1):71-84. doi: 10.1385/IR:27:1:71. Immunol Res. 2003. PMID: 12637769 Review.
T lymphocytes are the primary cells responsible for maintaining the immune system. There are many intricate mechanisms involved in the regulation of T cells and the integrin family of adhesive surface proteins plays a pivotal role in the control of T lymphocy
T lymphocytes are the primary cells responsible for maintaining the immune system. There are many intricate mechanisms involved in th
Glucosylceramide in T cells regulates the pathology of inflammatory bowel disease.
Komuro M, Nagane M, Endo R, Nakamura T, Miyamoto T, Niwa C, Fukuyama T, Harashima H, Aihara N, Kamiie J, Suzuki R, Yamashita T. Komuro M, et al. Among authors: miyamoto t. Biochem Biophys Res Commun. 2022 Apr 9;599:24-30. doi: 10.1016/j.bbrc.2022.02.004. Epub 2022 Feb 3. Biochem Biophys Res Commun. 2022. PMID: 35168060
Inflammatory bowel disease (IBD) is a chronic inflammatory disease in the colon characterized by excessive activation of T cells. Glycosphingolipids (GSLs) are composed of lipid rafts in cellular membranes, and their content is linked to immune cell function. ...Ad libitum …
Inflammatory bowel disease (IBD) is a chronic inflammatory disease in the colon characterized by excessive activation of T cells. Gly …
7,974 results