Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My NCBI Filters

Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1971 1
1972 1
1975 15
1976 11
1977 17
1978 17
1979 24
1980 30
1981 36
1982 32
1983 41
1984 37
1985 56
1986 58
1987 56
1988 58
1989 81
1990 99
1991 109
1992 111
1993 149
1994 177
1995 205
1996 230
1997 241
1998 320
1999 332
2000 380
2001 503
2002 520
2003 738
2004 922
2005 1180
2006 1226
2007 1472
2008 1827
2009 2041
2010 2572
2011 3145
2012 3802
2013 4527
2014 5119
2015 5523
2016 3583
2017 2505
2018 3917
2019 4542
2020 5341
2021 6091
2022 6857
2023 5869
2024 1057

Text availability

Article attribute

Article type

Publication date

Search Results

69,075 results

Results by year

Filters applied: . Clear all
Page 1
BCL6 promotes a stem-like CD8(+) T cell program in cancer via antagonizing BLIMP1.
Sun Q, Cai D, Liu D, Zhao X, Li R, Xu W, Xie B, Gou M, Wei K, Li Y, Huang J, Chi X, Wei P, Hao J, Guo X, Pan B, Fu Y, Ni L, Dong C. Sun Q, et al. Among authors: wei p, wei k. Sci Immunol. 2023 Oct 27;8(88):eadh1306. doi: 10.1126/sciimmunol.adh1306. Epub 2023 Oct 20. Sci Immunol. 2023. PMID: 37862431
Overcoming CD8(+) T cell exhaustion is critical in cancer immunotherapy. Recently, an intratumor stem/progenitor-like CD8(+) T cell (T(prog) cell) population that mediates the persistence of antitumor responses has been defined, which can further develop into …
Overcoming CD8(+) T cell exhaustion is critical in cancer immunotherapy. Recently, an intratumor stem/progenitor-like CD8(+) T …
In vivo CRISPR screening reveals nutrient signaling processes underpinning CD8(+) T cell fate decisions.
Huang H, Zhou P, Wei J, Long L, Shi H, Dhungana Y, Chapman NM, Fu G, Saravia J, Raynor JL, Liu S, Palacios G, Wang YD, Qian C, Yu J, Chi H. Huang H, et al. Among authors: wei j. Cell. 2021 Mar 4;184(5):1245-1261.e21. doi: 10.1016/j.cell.2021.02.021. Epub 2021 Feb 25. Cell. 2021. PMID: 33636132 Free PMC article.
How early events in effector T cell (T(EFF)) subsets tune memory T cell (T(MEM)) responses remains incompletely understood. Here, we systematically investigated metabolic factors in fate determination of T(EFF) and T(MEM) cells using in v …
How early events in effector T cell (T(EFF)) subsets tune memory T cell (T(MEM)) responses remains incompletely …
Depletion of BATF in CAR-T cells enhances antitumor activity by inducing resistance against exhaustion and formation of central memory cells.
Zhang X, Zhang C, Qiao M, Cheng C, Tang N, Lu S, Sun W, Xu B, Cao Y, Wei X, Wang Y, Han W, Wang H. Zhang X, et al. Among authors: wei x. Cancer Cell. 2022 Nov 14;40(11):1407-1422.e7. doi: 10.1016/j.ccell.2022.09.013. Epub 2022 Oct 13. Cancer Cell. 2022. PMID: 36240777 Free article.
Chimeric antigen receptor (CAR) T cell therapy has limited efficacy against solid tumors, and one major challenge is T cell exhaustion. ...In different types of CAR-T cells and mouse OT-1 cells, loss of BATF endows T cells with improved resistance to e …
Chimeric antigen receptor (CAR) T cell therapy has limited efficacy against solid tumors, and one major challenge is T cell ex …
Regulatory T cells in tumor microenvironment: new mechanisms, potential therapeutic strategies and future prospects.
Li C, Jiang P, Wei S, Xu X, Wang J. Li C, et al. Among authors: wei s. Mol Cancer. 2020 Jul 17;19(1):116. doi: 10.1186/s12943-020-01234-1. Mol Cancer. 2020. PMID: 32680511 Free PMC article. Review.
Regulatory T cells (Tregs) characterized by the expression of the master transcription factor forkhead box protein p3 (Foxp3) suppress anticancer immunity, thereby hindering protective immunosurveillance of tumours and hampering effective antitumour immune responses in tum …
Regulatory T cells (Tregs) characterized by the expression of the master transcription factor forkhead box protein p3 (Foxp3) suppres …
A trispecific antibody targeting HER2 and T cells inhibits breast cancer growth via CD4 cells.
Seung E, Xing Z, Wu L, Rao E, Cortez-Retamozo V, Ospina B, Chen L, Beil C, Song Z, Zhang B, Levit M, Deng G, Hebert A, Kirby P, Li A, Poulton EJ, Vicente R, Garrigou A, Piepenhagen P, Ulinski G, Sanicola-Nadel M, Bangari DS, Qiu H, Pao L, Wiederschain D, Wei R, Yang ZY, Nabel GJ. Seung E, et al. Among authors: wei r. Nature. 2022 Mar;603(7900):328-334. doi: 10.1038/s41586-022-04439-0. Epub 2022 Feb 23. Nature. 2022. PMID: 35197632
Effective antitumour immunity depends on the orchestration of potent T cell responses against malignancies(1). Regression of human cancers has been induced by immune checkpoint inhibitors, T cell engagers or chimeric antigen receptor T cell therapies(2-4). Al …
Effective antitumour immunity depends on the orchestration of potent T cell responses against malignancies(1). Regression of human ca …
CD4(+) T-cell epitope-based heterologous prime-boost vaccination potentiates anti-tumor immunity and PD-1/PD-L1 immunotherapy.
Xiao M, Xie L, Cao G, Lei S, Wang P, Wei Z, Luo Y, Fang J, Yang X, Huang Q, Xu L, Guo J, Wen S, Wang Z, Wu Q, Tang J, Wang L, Chen X, Chen C, Zhang Y, Yao W, Ye J, He R, Huang J, Ye L. Xiao M, et al. Among authors: wei z. J Immunother Cancer. 2022 May;10(5):e004022. doi: 10.1136/jitc-2021-004022. J Immunother Cancer. 2022. PMID: 35580929 Free PMC article.
BACKGROUND: Antitumor therapeutic vaccines are generally based on antigenic epitopes presented by major histocompatibility complex (MHC-I) molecules to induce tumor-specific CD8(+) T cells. Paradoxically, continuous T cell receptor (TCR) stimulation from tumor-deriv …
BACKGROUND: Antitumor therapeutic vaccines are generally based on antigenic epitopes presented by major histocompatibility complex (MHC-I) m …
Characteristics of premanufacture CD8(+)T cells determine CAR-T efficacy in patients with diffuse large B-cell lymphoma.
Wang Y, Tong C, Lu Y, Wu Z, Guo Y, Liu Y, Wei J, Wang C, Yang Q, Han W. Wang Y, et al. Among authors: wei j. Signal Transduct Target Ther. 2023 Oct 25;8(1):409. doi: 10.1038/s41392-023-01659-2. Signal Transduct Target Ther. 2023. PMID: 37875502 Free PMC article.
To reveal changes in CAR-T cell therapy and identify response biomarkers, we conducted a retrospective analysis of pre-manufacture source T cells and CAR-T cell products and their association with outcome in 58 patients with r/rDLBCL who received tandem CD19/ …
To reveal changes in CAR-T cell therapy and identify response biomarkers, we conducted a retrospective analysis of pre-manufacture so …
Delivery of CD47 blocker SIRPalpha-Fc by CAR-T cells enhances antitumor efficacy.
Chen H, Yang Y, Deng Y, Wei F, Zhao Q, Liu Y, Liu Z, Yu B, Huang Z. Chen H, et al. Among authors: wei f. J Immunother Cancer. 2022 Feb;10(2):e003737. doi: 10.1136/jitc-2021-003737. J Immunother Cancer. 2022. PMID: 35110357 Free PMC article.
Given the antitumor activity against preclinical model of CD47-blocking to induce the innate and adaptive immune system in the tumor microenvironment, here we developed a CAR-T cell secreting CD47 blocker signal regulatory protein alpha (SIRPalpha)-Fc fusion protein (Sirf …
Given the antitumor activity against preclinical model of CD47-blocking to induce the innate and adaptive immune system in the tumor microen …
Follicular CXCR5- expressing CD8(+) T cells curtail chronic viral infection.
He R, Hou S, Liu C, Zhang A, Bai Q, Han M, Yang Y, Wei G, Shen T, Yang X, Xu L, Chen X, Hao Y, Wang P, Zhu C, Ou J, Liang H, Ni T, Zhang X, Zhou X, Deng K, Chen Y, Luo Y, Xu J, Qi H, Wu Y, Ye L. He R, et al. Among authors: wei g. Nature. 2016 Aug 2;537(7620):412-428. doi: 10.1038/nature19317. Nature. 2016. PMID: 27501245
During chronic viral infection, virus-specific CD8(+) T cells become exhausted, exhibit poor effector function and lose memory potential. ...In patients with HIV, we also identified a virus-specific CXCR5(+) CD8(+) T-cell subset, and its number was inversely correla …
During chronic viral infection, virus-specific CD8(+) T cells become exhausted, exhibit poor effector function and lose memory potent …
Arthritis flares mediated by tissue-resident memory T cells in the joint.
Chang MH, Levescot A, Nelson-Maney N, Blaustein RB, Winden KD, Morris A, Wactor A, Balu S, Grieshaber-Bouyer R, Wei K, Henderson LA, Iwakura Y, Clark RA, Rao DA, Fuhlbrigge RC, Nigrovic PA. Chang MH, et al. Among authors: wei k. Cell Rep. 2021 Oct 26;37(4):109902. doi: 10.1016/j.celrep.2021.109902. Cell Rep. 2021. PMID: 34706228 Free PMC article.
Pursuing this intriguing pattern, we show that arthritis recurrence is mediated by long-lived synovial resident memory T cells (T(RM)). In three murine models, CD8+ cells bearing T(RM) markers remain in previously inflamed joints during remission. ...Correspo …
Pursuing this intriguing pattern, we show that arthritis recurrence is mediated by long-lived synovial resident memory T cells (T …
69,075 results
You have reached the last available page of results. Please see the User Guide for more information.