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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1964 1
1965 4
1967 2
1969 1
1970 1
1971 1
1972 1
1973 3
1974 4
1975 8
1976 14
1977 15
1978 12
1979 29
1980 65
1981 115
1982 123
1983 165
1984 170
1985 182
1986 196
1987 212
1988 279
1989 283
1990 293
1991 337
1992 327
1993 303
1994 374
1995 379
1996 418
1997 437
1998 508
1999 598
2000 649
2001 599
2002 694
2003 675
2004 773
2005 784
2006 846
2007 905
2008 963
2009 951
2010 1021
2011 1124
2012 1177
2013 1239
2014 1205
2015 1143
2016 750
2017 548
2018 782
2019 852
2020 875
2021 956
2022 944
2023 659
2024 104

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24,606 results

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Page 1
Mechanism of activation-induced cell death of T cells and regulation of FasL expression.
Arakaki R, Yamada A, Kudo Y, Hayashi Y, Ishimaru N. Arakaki R, et al. Among authors: yamada a. Crit Rev Immunol. 2014;34(4):301-14. doi: 10.1615/critrevimmunol.2014009988. Crit Rev Immunol. 2014. PMID: 24941158 Review.
Activation-induced cell death (AICD) of T cells is a process for regulating the peripheral immune system. ...In healthy humans, overactivated or autoreactive T cells are harmful and are eliminated to maintain the immune system. ...
Activation-induced cell death (AICD) of T cells is a process for regulating the peripheral immune system. ...In healthy humans, overa …
Generation of rejuvenated antigen-specific T cells by reprogramming to pluripotency and redifferentiation.
Nishimura T, Kaneko S, Kawana-Tachikawa A, Tajima Y, Goto H, Zhu D, Nakayama-Hosoya K, Iriguchi S, Uemura Y, Shimizu T, Takayama N, Yamada D, Nishimura K, Ohtaka M, Watanabe N, Takahashi S, Iwamoto A, Koseki H, Nakanishi M, Eto K, Nakauchi H. Nishimura T, et al. Among authors: yamada d. Cell Stem Cell. 2013 Jan 3;12(1):114-26. doi: 10.1016/j.stem.2012.11.002. Cell Stem Cell. 2013. PMID: 23290140 Free article.
In an effort to overcome this problem, we reprogrammed clonally expanded antigen-specific CD8(+) T cells from an HIV-1-infected patient to pluripotency. The T cell-derived induced pluripotent stem cells were then redifferentiated into CD8(+) T cells that had …
In an effort to overcome this problem, we reprogrammed clonally expanded antigen-specific CD8(+) T cells from an HIV-1-infected patie …
A phase 1 trial of NY-ESO-1-specific TCR-engineered T-cell therapy combined with a lymph node-targeting nanoparticulate peptide vaccine for the treatment of advanced soft tissue sarcoma.
Ishihara M, Nishida Y, Kitano S, Kawai A, Muraoka D, Momose F, Harada N, Miyahara Y, Seo N, Hattori H, Takada K, Emori M, Kakunaga S, Endo M, Matsumoto Y, Sasada T, Sato E, Yamada T, Matsumine A, Nagata Y, Watanabe T, Kageyama S, Shiku H. Ishihara M, et al. Among authors: yamada t. Int J Cancer. 2023 Jun 15;152(12):2554-2566. doi: 10.1002/ijc.34453. Epub 2023 Feb 17. Int J Cancer. 2023. PMID: 36727538 Clinical Trial.
The efficacy of immune checkpoint inhibitors is limited in refractory solid tumors. T-cell receptor gene-modified T (TCR-T)-cell therapy has attracted attention as a new immunotherapy for refractory cold tumors. ...The pullulan nanogel:LPA vaccine contains an …
The efficacy of immune checkpoint inhibitors is limited in refractory solid tumors. T-cell receptor gene-modified T (TCR-T …
Adaptive immunity in the joint of rheumatoid arthritis.
Yamada H. Yamada H. Immunol Med. 2022 Mar;45(1):1-11. doi: 10.1080/25785826.2021.1930371. Epub 2021 May 30. Immunol Med. 2022. PMID: 34053404 Review.
In the former, a recently identified CD4 T cell subset, peripheral helper T (Tph), which is characterized by the expression of PD-1 and production of CXCL13 and IL-21, is implicated, while the latter might be mediated by Th1-like CD4 T cell subsets that can p …
In the former, a recently identified CD4 T cell subset, peripheral helper T (Tph), which is characterized by the expression of …
The Search for the Pathogenic T Cells in the Joint of Rheumatoid Arthritis: Which T-Cell Subset Drives Autoimmune Inflammation?
Yamada H. Yamada H. Int J Mol Sci. 2023 Apr 8;24(8):6930. doi: 10.3390/ijms24086930. Int J Mol Sci. 2023. PMID: 37108093 Free PMC article. Review.
Historically, T-helper (Th)1 and Th17 cells are hypothesized to be pathogenic T cells in RA joints; however, lines of evidence do not fully support this hypothesis, showing polyfunctionality of the T cells. Recent progress in single-cell analysis technology h …
Historically, T-helper (Th)1 and Th17 cells are hypothesized to be pathogenic T cells in RA joints; however, lines of evidence …
Comprehensive genomic analysis identifying heterogeneity in peripheral T-cell lymphoma.
Yoshida N, Yamada K, Ohshima K. Yoshida N, et al. Among authors: yamada k. Cancer Sci. 2021 Apr;112(4):1339-1347. doi: 10.1111/cas.14849. Epub 2021 Feb 25. Cancer Sci. 2021. PMID: 33576080 Free PMC article. Review.
Peripheral T-cell lymphoma (PTCL) is a heterogeneous entity generally with a poor prognosis. ...ATLL is an incurable T-cell malignancy induced by human T-cell lymphotropic virus type 1 (HTLV-1). ...
Peripheral T-cell lymphoma (PTCL) is a heterogeneous entity generally with a poor prognosis. ...ATLL is an incurable T-cell ma …
Development of a Novel CD26-Targeted Chimeric Antigen Receptor T-Cell Therapy for CD26-Expressing T-Cell Malignancies.
Kobayashi E, Kamihara Y, Arai M, Wada A, Kikuchi S, Hatano R, Iwao N, Susukida T, Ozawa T, Adachi Y, Kishi H, Dang NH, Yamada T, Hayakawa Y, Morimoto C, Sato T. Kobayashi E, et al. Among authors: yamada t. Cells. 2023 Aug 14;12(16):2059. doi: 10.3390/cells12162059. Cells. 2023. PMID: 37626869 Free PMC article.
On the other hand, the development of CAR-T-cell therapy for T-cell malignancies is in its nascent stage. ...CD26-2G/3G was also highly effective against T-cell lymphoma cells derived from patients. In an in vivo mouse model in which a T-cell lymphoma …
On the other hand, the development of CAR-T-cell therapy for T-cell malignancies is in its nascent stage. ...CD26-2G/3G was al …
T Helper Cell Subsets in Experimental Lung Allograft Rejection.
Yamada Y, Brüstle K, Jungraithmayr W. Yamada Y, et al. J Surg Res. 2019 Jan;233:74-81. doi: 10.1016/j.jss.2018.07.073. Epub 2018 Aug 17. J Surg Res. 2019. PMID: 30502290 Review.
RESULTS: One of the most important immune cells responsible for rejection are T cells. Beside alloreactive CD8+ T cells, CD4+ T cells play a key role during the evolvement of allograft rejection. Certain subsets of these allograft CD4+ T cells have bee …
RESULTS: One of the most important immune cells responsible for rejection are T cells. Beside alloreactive CD8+ T cells, CD4+ …
Unique Phenotypes and Functions of Follicular Helper T Cells and Regulatory T Cells in Sjogren's Syndrome.
Saito M, Otsuka K, Ushio A, Yamada A, Arakaki R, Kudo Y, Ishimaru N. Saito M, et al. Among authors: yamada a. Curr Rheumatol Rev. 2018;14(3):239-245. doi: 10.2174/1573397113666170125122858. Curr Rheumatol Rev. 2018. PMID: 28124612 Free PMC article. Review.
Sjogren's syndrome (SS) is a T cell-mediated autoimmune disease of the systemic exocrine glands, such as salivary and lacrimal glands. ...In this review, we focused on follicular helper T cells related to antibody production and regulatory T cells to control …
Sjogren's syndrome (SS) is a T cell-mediated autoimmune disease of the systemic exocrine glands, such as salivary and lacrimal glands …
Possible Immune Regulation of Natural Killer T Cells in a Murine Model of Metal Ion-Induced Allergic Contact Dermatitis.
Kumagai K, Horikawa T, Shigematsu H, Matsubara R, Kitaura K, Eguchi T, Kobayashi H, Nakasone Y, Sato K, Yamada H, Suzuki S, Hamada Y, Suzuki R. Kumagai K, et al. Among authors: yamada h. Int J Mol Sci. 2016 Jan 12;17(1):87. doi: 10.3390/ijms17010087. Int J Mol Sci. 2016. PMID: 26771600 Free PMC article. Review.
Metal often causes delayed-type hypersensitivity reactions, which are possibly mediated by accumulating T cells in the inflamed skin, called irritant or allergic contact dermatitis. However, accumulating T cells during development of a metal allergy are poorly chara …
Metal often causes delayed-type hypersensitivity reactions, which are possibly mediated by accumulating T cells in the inflamed skin, …
24,606 results
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