Search Page

1

Cite

Share

NAD⁺ metabolism and its roles in cellular processes during ageing.

Covarrubias AJ, Perrone R, Grozio A, Verdin E. Covarrubias AJ, et al. Nat Rev Mol Cell Biol. 2021 Feb;22(2):119-141. doi: 10.1038/s41580-020-00313-x. Epub 2020 Dec 22. Nat Rev Mol Cell Biol. 2021. PMID: 33353981 Free PMC article. Review.

Cite

Share

2

Cite

Share

Mitochondrial Dysfunction Induces Senescence with a Distinct Secretory Phenotype.

Wiley CD, Velarde MC, Lecot P, Liu S, Sarnoski EA, Freund A, Shirakawa K, Lim HW, Davis SS, Ramanathan A, Gerencser AA, Verdin E, Campisi J. Wiley CD, et al. Cell Metab. 2016 Feb 9;23(2):303-14. doi: 10.1016/j.cmet.2015.11.011. Epub 2015 Dec 10. Cell Metab. 2016. PMID: 26686024 Free PMC article.

Cite

Share

3

Cite

Share

Protein Turnover in Aging and Longevity.

Basisty N, Meyer JG, Schilling B. Basisty N, et al. Proteomics. 2018 Mar;18(5-6):e1700108. doi: 10.1002/pmic.201700108. Proteomics. 2018. PMID: 29453826 Free PMC article. Review.

Cite

Share

4

Cite

Share

Ketogenic Diet Reduces Midlife Mortality and Improves Memory in Aging Mice.

Newman JC, Covarrubias AJ, Zhao M, Yu X, Gut P, Ng CP, Huang Y, Haldar S, Verdin E. Newman JC, et al. Cell Metab. 2017 Sep 5;26(3):547-557.e8. doi: 10.1016/j.cmet.2017.08.004. Cell Metab. 2017. PMID: 28877458 Free PMC article.

Cite

Share

5

Cite

Share

Senescent cells promote tissue NAD⁺ decline during ageing via the activation of CD38⁺ macrophages.

Covarrubias AJ, Kale A, Perrone R, Lopez-Dominguez JA, Pisco AO, Kasler HG, Schmidt MS, Heckenbach I, Kwok R, Wiley CD, Wong HS, Gibbs E, Iyer SS, Basisty N, Wu Q, Kim IJ, Silva E, Vitangcol K, Shin KO, Lee YM, Riley R, Ben-Sahra I, Ott M, Schilling B, Scheibye-Knudsen M, Ishihara K, Quake SR, Newman J, Brenner C, Campisi J, Verdin E. Covarrubias AJ, et al. Nat Metab. 2020 Nov;2(11):1265-1283. doi: 10.1038/s42255-020-00305-3. Epub 2020 Nov 16. Nat Metab. 2020. PMID: 33199924 Free PMC article.

Cite

Share

6

Cite

Share

The Mitochondrial Acylome Emerges: Proteomics, Regulation by Sirtuins, and Metabolic and Disease Implications.

Carrico C, Meyer JG, He W, Gibson BW, Verdin E. Carrico C, et al. Cell Metab. 2018 Mar 6;27(3):497-512. doi: 10.1016/j.cmet.2018.01.016. Cell Metab. 2018. PMID: 29514063 Free PMC article. Review.

Cite

Share

7

Cite

Share

A Muscle Stem Cell Support Group: Coordinated Cellular Responses in Muscle Regeneration.

Wosczyna MN, Rando TA. Wosczyna MN, et al. Dev Cell. 2018 Jul 16;46(2):135-143. doi: 10.1016/j.devcel.2018.06.018. Dev Cell. 2018. PMID: 30016618 Free PMC article. Review.

Cite

Share

8

Cite

Share

The Role of Advanced Glycation End Products in Aging and Metabolic Diseases: Bridging Association and Causality.

Chaudhuri J, Bains Y, Guha S, Kahn A, Hall D, Bose N, Gugliucci A, Kapahi P. Chaudhuri J, et al. Cell Metab. 2018 Sep 4;28(3):337-352. doi: 10.1016/j.cmet.2018.08.014. Cell Metab. 2018. PMID: 30184484 Free PMC article. Review.

Cite

Share

9

Cite

Share

MTOR regulates the pro-tumorigenic senescence-associated secretory phenotype by promoting IL1A translation.

Laberge RM, Sun Y, Orjalo AV, Patil CK, Freund A, Zhou L, Curran SC, Davalos AR, Wilson-Edell KA, Liu S, Limbad C, Demaria M, Li P, Hubbard GB, Ikeno Y, Javors M, Desprez PY, Benz CC, Kapahi P, Nelson PS, Campisi J. Laberge RM, et al. Nat Cell Biol. 2015 Aug;17(8):1049-61. doi: 10.1038/ncb3195. Epub 2015 Jul 6. Nat Cell Biol. 2015. PMID: 26147250 Free PMC article.

Cite

Share

10

Cite

Share

SIRT5 regulates the mitochondrial lysine succinylome and metabolic networks.

Rardin MJ, He W, Nishida Y, Newman JC, Carrico C, Danielson SR, Guo A, Gut P, Sahu AK, Li B, Uppala R, Fitch M, Riiff T, Zhu L, Zhou J, Mulhern D, Stevens RD, Ilkayeva OR, Newgard CB, Jacobson MP, Hellerstein M, Goetzman ES, Gibson BW, Verdin E. Rardin MJ, et al. Cell Metab. 2013 Dec 3;18(6):920-33. doi: 10.1016/j.cmet.2013.11.013. Cell Metab. 2013. PMID: 24315375 Free PMC article.

Cite

Share