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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1998 1
1999 1
2000 1
2002 3
2003 2
2004 2
2005 3
2006 3
2007 2
2008 4
2009 3
2010 4
2011 5
2012 7
2013 5
2014 18
2015 16
2016 19
2017 10
2018 15
2019 15
2020 5
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136 results
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Page 1
TREM2 Maintains Microglial Metabolic Fitness in Alzheimer's Disease.
Ulland TK, Song WM, Huang SC, Ulrich JD, Sergushichev A, Beatty WL, Loboda AA, Zhou Y, Cairns NJ, Kambal A, Loginicheva E, Gilfillan S, Cella M, Virgin HW, Unanue ER, Wang Y, Artyomov MN, Holtzman DM, Colonna M. Ulland TK, et al. Cell. 2017 Aug 10;170(4):649-663.e13. doi: 10.1016/j.cell.2017.07.023. Cell. 2017. PMID: 28802038 Free PMC article.
Optimized sgRNA design to maximize activity and minimize off-target effects of CRISPR-Cas9.
Doench JG, Fusi N, Sullender M, Hegde M, Vaimberg EW, Donovan KF, Smith I, Tothova Z, Wilen C, Orchard R, Virgin HW, Listgarten J, Root DE. Doench JG, et al. Nat Biotechnol. 2016 Feb;34(2):184-191. doi: 10.1038/nbt.3437. Epub 2016 Jan 18. Nat Biotechnol. 2016. PMID: 26780180 Free PMC article.
Discovery of a proteinaceous cellular receptor for a norovirus.
Orchard RC, Wilen CB, Doench JG, Baldridge MT, McCune BT, Lee YC, Lee S, Pruett-Miller SM, Nelson CA, Fremont DH, Virgin HW. Orchard RC, et al. Science. 2016 Aug 26;353(6302):933-6. doi: 10.1126/science.aaf1220. Epub 2016 Aug 18. Science. 2016. PMID: 27540007 Free PMC article.
Disease-specific alterations in the enteric virome in inflammatory bowel disease.
Norman JM, Handley SA, Baldridge MT, Droit L, Liu CY, Keller BC, Kambal A, Monaco CL, Zhao G, Fleshner P, Stappenbeck TS, McGovern DP, Keshavarzian A, Mutlu EA, Sauk J, Gevers D, Xavier RJ, Wang D, Parkes M, Virgin HW. Norman JM, et al. Cell. 2015 Jan 29;160(3):447-60. doi: 10.1016/j.cell.2015.01.002. Epub 2015 Jan 22. Cell. 2015. PMID: 25619688 Free PMC article. Clinical Trial.
Molecular characterization of LC3-associated phagocytosis reveals distinct roles for Rubicon, NOX2 and autophagy proteins.
Martinez J, Malireddi RK, Lu Q, Cunha LD, Pelletier S, Gingras S, Orchard R, Guan JL, Tan H, Peng J, Kanneganti TD, Virgin HW, Green DR. Martinez J, et al. Nat Cell Biol. 2015 Jul;17(7):893-906. doi: 10.1038/ncb3192. Epub 2015 Jun 22. Nat Cell Biol. 2015. PMID: 26098576 Free PMC article.
Zika virus infection damages the testes in mice.
Govero J, Esakky P, Scheaffer SM, Fernandez E, Drury A, Platt DJ, Gorman MJ, Richner JM, Caine EA, Salazar V, Moley KH, Diamond MS. Govero J, et al. Nature. 2016 Dec 15;540(7633):438-442. doi: 10.1038/nature20556. Epub 2016 Oct 31. Nature. 2016. PMID: 27798603 Free PMC article.
A Mouse Model of Zika Virus Pathogenesis.
Lazear HM, Govero J, Smith AM, Platt DJ, Fernandez E, Miner JJ, Diamond MS. Lazear HM, et al. Cell Host Microbe. 2016 May 11;19(5):720-30. doi: 10.1016/j.chom.2016.03.010. Epub 2016 Apr 5. Cell Host Microbe. 2016. PMID: 27066744 Free PMC article.
Zika Virus Infection during Pregnancy in Mice Causes Placental Damage and Fetal Demise.
Miner JJ, Cao B, Govero J, Smith AM, Fernandez E, Cabrera OH, Garber C, Noll M, Klein RS, Noguchi KK, Mysorekar IU, Diamond MS. Miner JJ, et al. Cell. 2016 May 19;165(5):1081-1091. doi: 10.1016/j.cell.2016.05.008. Epub 2016 May 11. Cell. 2016. PMID: 27180225 Free PMC article.
A CRISPR screen defines a signal peptide processing pathway required by flaviviruses.
Zhang R, Miner JJ, Gorman MJ, Rausch K, Ramage H, White JP, Zuiani A, Zhang P, Fernandez E, Zhang Q, Dowd KA, Pierson TC, Cherry S, Diamond MS. Zhang R, et al. Nature. 2016 Jul 7;535(7610):164-8. doi: 10.1038/nature18625. Epub 2016 Jun 17. Nature. 2016. PMID: 27383988 Free PMC article.
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