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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1993 1
1995 3
1998 1
1999 1
2001 1
2002 3
2003 3
2004 7
2005 8
2006 7
2007 8
2008 12
2009 25
2010 28
2011 25
2012 16
2013 19
2014 11
2015 13
2016 16
2017 12
2018 18
2019 19
2020 13
2021 1
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240 results
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Page 1
DARK Classics in Chemical Neuroscience: Cocaine.
Drake LR, Scott PJH. Drake LR, et al. ACS Chem Neurosci. 2018 Oct 17;9(10):2358-2372. doi: 10.1021/acschemneuro.8b00117. Epub 2018 Apr 24. ACS Chem Neurosci. 2018. PMID: 29630337 Free PMC article. Review.
Structure of an endosomal signaling GPCR-G protein-β-arrestin megacomplex.
Nguyen AH, Thomsen ARB, Cahill TJ 3rd, Huang R, Huang LY, Marcink T, Clarke OB, Heissel S, Masoudi A, Ben-Hail D, Samaan F, Dandey VP, Tan YZ, Hong C, Mahoney JP, Triest S, Little J 4th, Chen X, Sunahara R, Steyaert J, Molina H, Yu Z, des Georges A, Lefkowitz RJ. Nguyen AH, et al. Nat Struct Mol Biol. 2019 Dec;26(12):1123-1131. doi: 10.1038/s41594-019-0330-y. Epub 2019 Nov 18. Nat Struct Mol Biol. 2019. PMID: 31740855 Free PMC article.
GPCR-G Protein-β-Arrestin Super-Complex Mediates Sustained G Protein Signaling.
Thomsen ARB, Plouffe B, Cahill TJ 3rd, Shukla AK, Tarrasch JT, Dosey AM, Kahsai AW, Strachan RT, Pani B, Mahoney JP, Huang L, Breton B, Heydenreich FM, Sunahara RK, Skiniotis G, Bouvier M, Lefkowitz RJ. Thomsen ARB, et al. Cell. 2016 Aug 11;166(4):907-919. doi: 10.1016/j.cell.2016.07.004. Epub 2016 Aug 4. Cell. 2016. PMID: 27499021 Free PMC article.
Structural insights into binding specificity, efficacy and bias of a β2AR partial agonist.
Masureel M, Zou Y, Picard LP, van der Westhuizen E, Mahoney JP, Rodrigues JPGLM, Mildorf TJ, Dror RO, Shaw DE, Bouvier M, Pardon E, Steyaert J, Sunahara RK, Weis WI, Zhang C, Kobilka BK. Masureel M, et al. Nat Chem Biol. 2018 Nov;14(11):1059-1066. doi: 10.1038/s41589-018-0145-x. Epub 2018 Oct 16. Nat Chem Biol. 2018. PMID: 30327561 Free PMC article.
Conformational biosensors reveal GPCR signalling from endosomes.
Irannejad R, Tomshine JC, Tomshine JR, Chevalier M, Mahoney JP, Steyaert J, Rasmussen SG, Sunahara RK, El-Samad H, Huang B, von Zastrow M. Irannejad R, et al. Nature. 2013 Mar 28;495(7442):534-8. doi: 10.1038/nature12000. Epub 2013 Mar 20. Nature. 2013. PMID: 23515162 Free PMC article.
TTK inhibition radiosensitizes basal-like breast cancer through impaired homologous recombination.
Chandler BC, Moubadder L, Ritter CL, Liu M, Cameron M, Wilder-Romans K, Zhang A, Pesch AM, Michmerhuizen AR, Hirsh N, Androsiglio M, Ward T, Olsen E, Niknafs YS, Merajver S, Thomas DG, Brown PH, Lawrence TS, Nyati S, Pierce LJ, Chinnaiyan A, Speers C. Chandler BC, et al. J Clin Invest. 2020 Feb 3;130(2):958-973. doi: 10.1172/JCI130435. J Clin Invest. 2020. PMID: 31961339 Free PMC article.
Allosteric coupling from G protein to the agonist-binding pocket in GPCRs.
DeVree BT, Mahoney JP, Vélez-Ruiz GA, Rasmussen SG, Kuszak AJ, Edwald E, Fung JJ, Manglik A, Masureel M, Du Y, Matt RA, Pardon E, Steyaert J, Kobilka BK, Sunahara RK. DeVree BT, et al. Nature. 2016 Jul 7;535(7610):182-6. doi: 10.1038/nature18324. Epub 2016 Jun 29. Nature. 2016. PMID: 27362234 Free PMC article.
240 results
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