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Application of gene-editing technologies to HIV-1.
Drake MJ, Bates P. Drake MJ, et al. Curr Opin HIV AIDS. 2015 Mar;10(2):123-7. doi: 10.1097/COH.0000000000000139. Curr Opin HIV AIDS. 2015. PMID: 25612322 Free PMC article. Review.
The Notch1 transcriptional activation domain is required for development and reveals a novel role for Notch1 signaling in fetal hematopoietic stem cells.
Gerhardt DM, Pajcini KV, D'altri T, Tu L, Jain R, Xu L, Chen MJ, Rentschler S, Shestova O, Wertheim GB, Tobias JW, Kluk M, Wood AW, Aster JC, Gimotty PA, Epstein JA, Speck N, Bigas A, Pear WS. Gerhardt DM, et al. Genes Dev. 2014 Mar 15;28(6):576-93. doi: 10.1101/gad.227496.113. Genes Dev. 2014. PMID: 24637115 Free PMC article.
The major cellular sterol regulatory pathway is required for Andes virus infection.
Petersen J, Drake MJ, Bruce EA, Riblett AM, Didigu CA, Wilen CB, Malani N, Male F, Lee FH, Bushman FD, Cherry S, Doms RW, Bates P, Briley K Jr. Petersen J, et al. PLoS Pathog. 2014 Feb 6;10(2):e1003911. doi: 10.1371/journal.ppat.1003911. eCollection 2014 Feb. PLoS Pathog. 2014. PMID: 24516383 Free PMC article.
Dicer-2 processes diverse viral RNA species.
Sabin LR, Zheng Q, Thekkat P, Yang J, Hannon GJ, Gregory BD, Tudor M, Cherry S. Sabin LR, et al. PLoS One. 2013;8(2):e55458. doi: 10.1371/journal.pone.0055458. Epub 2013 Feb 12. PLoS One. 2013. PMID: 23424633 Free PMC article.