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Page 1
Induction of tissue factor in the arterial wall during recurrent thrombus formation.
D'Andrea D, Ravera M, Golino P, Rosica A, De Felice M, Ragni M, Cirillo P, Vigorito F, Corcione N, Tommasini P, Gargiulo A, Piro O, Calabró P, Chiariello M. D'Andrea D, et al. Among authors: vigorito f. Arterioscler Thromb Vasc Biol. 2003 Sep 1;23(9):1684-9. doi: 10.1161/01.ATV.0000087034.22709.5F. Epub 2003 Jul 17. Arterioscler Thromb Vasc Biol. 2003. PMID: 12869352
No TF expression was observed in the media of control vessels, whereas a progressive increase in TF mRNA and protein expression was observed in carotid arteries as CFVs progressed. No increase in TF expression was observed in animals pretreated with hirudin. …
No TF expression was observed in the media of control vessels, whereas a progressive increase in TF mRNA and protein expressio …
Antithrombotic effects of recombinant human, active site-blocked factor VIIa in a rabbit model of recurrent arterial thrombosis.
Golino P, Ragni M, Cirillo P, D'Andrea D, Scognamiglio A, Ravera A, Buono C, Ezban M, Corcione N, Vigorito F, Condorelli M, Chiariello M. Golino P, et al. Among authors: vigorito f. Circ Res. 1998 Jan 9-23;82(1):39-46. doi: 10.1161/01.res.82.1.39. Circ Res. 1998. PMID: 9440703
The extrinsic coagulation pathway is activated when circulating factor VII (FVII) gains access to tissue factor (TF) exposed as a consequence of vascular injury. Increasing evidence indicates that this TF-dependent activation of the coagulation plays an important ro …
The extrinsic coagulation pathway is activated when circulating factor VII (FVII) gains access to tissue factor (TF) exposed as a con …
Expression of exogenous tissue factor pathway inhibitor in vivo suppresses thrombus formation in injured rabbit carotid arteries.
Golino P, Cirillo P, Calabro' P, Ragni M, D'Andrea D, Avvedimento EV, Vigorito F, Corcione N, Loffredo F, Chiariello M. Golino P, et al. Among authors: vigorito f. J Am Coll Cardiol. 2001 Aug;38(2):569-76. doi: 10.1016/s0735-1097(01)01350-x. J Am Coll Cardiol. 2001. PMID: 11499754 Free article.
BACKGROUND: Acute coronary syndromes (unstable angina and acute myocardial infarction) are usually caused by atherosclerotic plaque rupture, with consequent activation of the coagulation cascade and circulating platelets. Tissue factor (TF) exposure represents an early eve …
BACKGROUND: Acute coronary syndromes (unstable angina and acute myocardial infarction) are usually caused by atherosclerotic plaque rupture, …
Long-lasting antithrombotic effects of a single dose of human recombinant, active site-blocked factor VII: insights into possible mechanism(s) of action.
Cirillo P, Golino P, Ragni M, D'andrea D, Calabró P, Corcione N, Vigorito F, Ravera M, Chiariello M. Cirillo P, et al. Among authors: vigorito f. J Thromb Haemost. 2003 May;1(5):992-8. doi: 10.1046/j.1538-7836.2003.00235.x. J Thromb Haemost. 2003. PMID: 12871367 Free article.
Tissue factor (TF) is important in initiating intravascular thrombosis. We demonstrated that active-site blocked factor VII (FVIIai) inhibits intravascular thrombosis for at least 6 h following a single injection, despite FVIIai plasma half-life was approximately 45 min. . …
Tissue factor (TF) is important in initiating intravascular thrombosis. We demonstrated that active-site blocked factor VII (FVIIai) …