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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1972 1
1973 1
1975 7
1976 3
1977 4
1978 9
1979 16
1980 21
1981 23
1982 14
1983 7
1984 15
1985 10
1986 9
1987 7
1988 9
1989 4
1990 4
1991 8
1992 5
1993 4
1994 5
1995 8
1996 7
1997 9
1998 13
1999 9
2000 11
2001 10
2002 15
2003 11
2004 16
2005 20
2006 30
2007 28
2008 33
2009 22
2010 15
2011 28
2012 28
2013 27
2014 33
2015 29
2016 41
2017 35
2018 59
2019 64
2020 74
2021 95
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887 results
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Did you mean the cancer (4,496,570 results)?
Multicenter, double-blind, randomized, placebo-controlled, parallel-group study of the efficacy, safety, and tolerability of THC:CBD extract and THC extract in patients with intractable cancer-related pain.
Johnson JR, Burnell-Nugent M, Lossignol D, Ganae-Motan ED, Potts R, Fallon MT. Johnson JR, et al. J Pain Symptom Manage. 2010 Feb;39(2):167-79. doi: 10.1016/j.jpainsymman.2009.06.008. Epub 2009 Nov 5. J Pain Symptom Manage. 2010. PMID: 19896326 Free article. Clinical Trial.
This study compared the efficacy of a tetrahydrocannabinol:cannabidiol (THC:CBD) extract, a nonopioid analgesic endocannabinoid system modulator, and a THC extract, with placebo, in relieving pain in patients with advanced cancer. ...However, the results from …
This study compared the efficacy of a tetrahydrocannabinol:cannabidiol (THC:CBD) extract, a nonopioid analgesic endocannabinoid syste …
Beyond THC and Endocannabinoids.
Pacher P, Kogan NM, Mechoulam R. Pacher P, et al. Annu Rev Pharmacol Toxicol. 2020 Jan 6;60:637-659. doi: 10.1146/annurev-pharmtox-010818-021441. Epub 2019 Oct 3. Annu Rev Pharmacol Toxicol. 2020. PMID: 31580774 Review.
The Cannabis plant constituent cannabidiol (CBD) was found to exert beneficial effects in many preclinical disease models ranging from epilepsy, cardiovascular disease, inflammation, and autoimmunity to neurodegenerative and kidney diseases and cancer. CBD was recently app …
The Cannabis plant constituent cannabidiol (CBD) was found to exert beneficial effects in many preclinical disease models ranging from epile …
An open-label extension study to investigate the long-term safety and tolerability of THC/CBD oromucosal spray and oromucosal THC spray in patients with terminal cancer-related pain refractory to strong opioid analgesics.
Johnson JR, Lossignol D, Burnell-Nugent M, Fallon MT. Johnson JR, et al. J Pain Symptom Manage. 2013 Aug;46(2):207-18. doi: 10.1016/j.jpainsymman.2012.07.014. Epub 2012 Nov 8. J Pain Symptom Manage. 2013. PMID: 23141881 Free article. Clinical Trial.
CONTEXT: Chronic pain in patients with advanced cancer poses a serious clinical challenge. The delta9-tetrahydrocannabinol (THC)/cannabidiol (CBD) oromucosal spray (U.S. ...OBJECTIVES: This follow-up study investigated the long-term safety and tolerability of …
CONTEXT: Chronic pain in patients with advanced cancer poses a serious clinical challenge. The delta9-tetrahydrocannabinol (THC
Practical considerations in medical cannabis administration and dosing.
MacCallum CA, Russo EB. MacCallum CA, et al. Eur J Intern Med. 2018 Mar;49:12-19. doi: 10.1016/j.ejim.2018.01.004. Epub 2018 Jan 4. Eur J Intern Med. 2018. PMID: 29307505 Review.
In this article, the authors endeavour to present concise data on cannabis pharmacology related to tetrahydrocannabinol (THC), cannabidiol (CBD) et al., methods of administration (smoking, vaporisation, oral), and dosing recommendations. ...CBD, in contrast to THC, …
In this article, the authors endeavour to present concise data on cannabis pharmacology related to tetrahydrocannabinol (THC), cannab …
Medical marijuana for cancer.
Kramer JL. Kramer JL. CA Cancer J Clin. 2015 Mar;65(2):109-22. doi: 10.3322/caac.21260. Epub 2014 Dec 10. CA Cancer J Clin. 2015. PMID: 25503438 Free article. Review.
Investigations into these medicinal properties has led to the development of cannabinoid pharmaceuticals such as dronabinol, nabilone, and nabiximols. Dronabinol is best studied in the treatment of nausea secondary to cancer chemotherapy and anorexia associat …
Investigations into these medicinal properties has led to the development of cannabinoid pharmaceuticals such as dronabinol, nabilone …
Pharmacokinetics and pharmacodynamics of cannabinoids.
Grotenhermen F. Grotenhermen F. Clin Pharmacokinet. 2003;42(4):327-60. doi: 10.2165/00003088-200342040-00003. Clin Pharmacokinet. 2003. PMID: 12648025 Review.
Delta(9)-Tetrahydrocannabinol (THC) is the main source of the pharmacological effects caused by the consumption of cannabis, both the marijuana-like action and the medicinal benefits of the plant. However, its acid metabolite THC-COOH, the non-psychotropic cannabidi …
Delta(9)-Tetrahydrocannabinol (THC) is the main source of the pharmacological effects caused by the consumption of cannabis, both the …
[Cannabidiol in cancer treatment].
Likar R, Köstenberger M, Nahler G. Likar R, et al. Schmerz. 2020 Apr;34(2):117-122. doi: 10.1007/s00482-019-00438-9. Schmerz. 2020. PMID: 31897700 Review. German.
BACKGROUND: Cannabis was used for cancer patients as early as about 2500 years ago. Experimental studies demonstrated tumor-inhibiting activities of various cannabinoids more than 40 years ago. In view of the status of tetrahydrocannabinol (THC) as a regulated subst …
BACKGROUND: Cannabis was used for cancer patients as early as about 2500 years ago. Experimental studies demonstrated tumor-inhibitin …
Taming THC: potential cannabis synergy and phytocannabinoid-terpenoid entourage effects.
Russo EB. Russo EB. Br J Pharmacol. 2011 Aug;163(7):1344-64. doi: 10.1111/j.1476-5381.2011.01238.x. Br J Pharmacol. 2011. PMID: 21749363 Free PMC article. Review.
Tetrahydrocannabinol (THC) has been the primary focus of cannabis research since 1964, when Raphael Mechoulam isolated and synthesized it. ...Scientific evidence is presented for non-cannabinoid plant components as putative antidotes to intoxicating effects of THC t …
Tetrahydrocannabinol (THC) has been the primary focus of cannabis research since 1964, when Raphael Mechoulam isolated and synthesize …
Cannabis and cannabinoids in cancer pain management.
Meng H, Dai T, Hanlon JG, Downar J, Alibhai SMH, Clarke H. Meng H, et al. Curr Opin Support Palliat Care. 2020 Jun;14(2):87-93. doi: 10.1097/SPC.0000000000000493. Curr Opin Support Palliat Care. 2020. PMID: 32332209 Review.
PURPOSE OF REVIEW: An increasing number of patients are turning to cannabis and cannabinoids for management of their palliative and nonpalliative cancer pain and other cancer-related symptoms. Canadians have a legal framework for access to medical cannabis, which pr …
PURPOSE OF REVIEW: An increasing number of patients are turning to cannabis and cannabinoids for management of their palliative and nonpalli …
Oral medicinal cannabinoids to relieve symptom burden in the palliative care of patients with advanced cancer: a double-blind, placebo-controlled, randomised clinical trial of efficacy and safety of 1:1 delta-9-tetrahydrocannabinol (THC) and cannabidiol (CBD).
Hardy J, Haywood A, Gogna G, Martin J, Yates P, Greer R, Good P. Hardy J, et al. Trials. 2020 Jul 6;21(1):611. doi: 10.1186/s13063-020-04541-6. Trials. 2020. PMID: 32631447 Free PMC article.
This study aims to define the role of a 1:1 delta-9-tetrahydrocannabinol/cannabidiol (THC/CBD) cannabinoid preparation in the management of symptom burden in patients with advanced cancer undergoing standard palliative care. ...DISCUSSION: This will be the first pla …
This study aims to define the role of a 1:1 delta-9-tetrahydrocannabinol/cannabidiol (THC/CBD) cannabinoid preparation in the managem …
887 results