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ISPAD Clinical Practice Consensus Guidelines 2022: Type 2 diabetes in children and adolescents.
Shah AS, Zeitler PS, Wong J, Pena AS, Wicklow B, Arslanian S, Chang N, Fu J, Dabadghao P, Pinhas-Hamiel O, Urakami T, Craig ME. Shah AS, et al. Pediatr Diabetes. 2022 Nov;23(7):872-902. doi: 10.1111/pedi.13409. Epub 2022 Sep 25. Pediatr Diabetes. 2022. PMID: 36161685 Review.
Since the 2018 ISPAD guidelines on this topic, follow-up of large cohorts from around the globe have continued informing the current incidence and prevalence of co-morbidities and complications in young adults with youth-onset type 2 diabetes (T2D). .. …
Since the 2018 ISPAD guidelines on this topic, follow-up of large cohorts from around the globe have continued informing the current …
Insulin clearance at randomisation and in response to treatment in youth with type 2 diabetes: a secondary analysis of the TODAY randomised clinical trial.
Nadeau KJ, Arslanian SA, Bacha F, Caprio S, Chao LC, Farrell R, Hughan KS, Rayas M, Tung M, Cross K, El Ghormli L; TODAY Study Group. Nadeau KJ, et al. Diabetologia. 2025 Mar;68(3):676-687. doi: 10.1007/s00125-024-06327-w. Epub 2024 Dec 20. Diabetologia. 2025. PMID: 39706874 Free PMC article. Clinical Trial.
AIMS/HYPOTHESIS: Insulin resistance and compensatory hyperinsulinaemia are core features leading to beta cell failure in youth-onset type 2 diabetes. Insulin clearance (IC) is also a key regulator of insulin concentrations, but few data exist on IC in youth-o …
AIMS/HYPOTHESIS: Insulin resistance and compensatory hyperinsulinaemia are core features leading to beta cell failure in youth-onset type …
Monogenic diabetes in overweight and obese youth diagnosed with type 2 diabetes: the TODAY clinical trial.
Kleinberger JW, Copeland KC, Gandica RG, Haymond MW, Levitsky LL, Linder B, Shuldiner AR, Tollefsen S, White NH, Pollin TI. Kleinberger JW, et al. Genet Med. 2018 Jun;20(6):583-590. doi: 10.1038/gim.2017.150. Epub 2017 Oct 12. Genet Med. 2018. PMID: 29758564 Free PMC article. Clinical Trial.
This study was performed to estimate the prevalence of monogenic diabetes in a cohort of overweight/obese adolescents diagnosed with type 2 diabetes (T2D).MethodsSequencing using a custom monogenic diabetes gene panel was performed on a racially/ethnically di …
This study was performed to estimate the prevalence of monogenic diabetes in a cohort of overweight/obese adolescents diagnosed with type …
Adherence to a lifestyle program for youth with type 2 diabetes and its association with treatment outcome in the TODAY clinical trial.
Berkowitz RI, Marcus MD, Anderson BJ, Delahanty L, Grover N, Kriska A, Laffel L, Syme A, Venditti E, Van Buren DJ, Wilfley DE, Yasuda P, Hirst K; TODAY Study Group. Berkowitz RI, et al. Pediatr Diabetes. 2018 Mar;19(2):191-198. doi: 10.1111/pedi.12555. Epub 2017 Jun 30. Pediatr Diabetes. 2018. PMID: 28664624 Free PMC article. Clinical Trial.
OBJECTIVE: To assess the association of proxies of behavioral adherence to the Treatment Options for type 2 Diabetes in Adolescents and Youth (TODAY) lifestyle program with changes in glycemic control and obesity in a multi-ethnic sample of youth with …
OBJECTIVE: To assess the association of proxies of behavioral adherence to the Treatment Options for type 2 Diabetes in …
Weight change in the management of youth-onset type 2 diabetes: the TODAY clinical trial experience.
Marcus MD, Wilfley DE, El Ghormli L, Zeitler P, Linder B, Hirst K, Ievers-Landis CE, van Buren DJ, Walders-Abramson N; TODAY Study Group. Marcus MD, et al. Pediatr Obes. 2017 Aug;12(4):337-345. doi: 10.1111/ijpo.12148. Epub 2016 May 10. Pediatr Obes. 2017. PMID: 27161901 Free PMC article. Clinical Trial.
BACKGROUND: The Treatment Options for type 2 Diabetes in Adolescents and Youth (TODAY) clinical trial documented that metformin plus rosiglitazone, but not metformin plus lifestyle intervention, provided superior durability of glycemic co …
BACKGROUND: The Treatment Options for type 2 Diabetes in Adolescents and Youth (TODAY) clinical trial …
Design of a family-based lifestyle intervention for youth with type 2 diabetes: the TODAY study.
TODAY Study Group. TODAY Study Group. Int J Obes (Lond). 2010 Feb;34(2):217-26. doi: 10.1038/ijo.2009.195. Epub 2009 Oct 13. Int J Obes (Lond). 2010. PMID: 19823189 Free PMC article. Review.
Type 2 diabetes is associated with obesity and is increasing at an alarming rate in youth. Although weight loss through lifestyle change is one of the primary treatment recommendations for adults with type 2 diabetes, the efficacy of this …
Type 2 diabetes is associated with obesity and is increasing at an alarming rate in youth. Although weight loss through …
Development of type 2 diabetes mellitus in the obese adolescent: a growing challenge.
Caprio S. Caprio S. Endocr Pract. 2012 Sep-Oct;18(5):791-5. doi: 10.4158/EP12142.RA. Endocr Pract. 2012. PMID: 23047931 Review.
OBJECTIVE: To describe the metabolic phenotype of type 2 diabetes mellitus in youth and possible metabolic defects leading to its development with particular emphasis on fatty liver. ...We end briefly by discussing the current data available on treatme …
OBJECTIVE: To describe the metabolic phenotype of type 2 diabetes mellitus in youth and possible metabolic defec …
Youth-onset type 2 diabetes mellitus: lessons learned from the TODAY study.
Narasimhan S, Weinstock RS. Narasimhan S, et al. Mayo Clin Proc. 2014 Jun;89(6):806-16. doi: 10.1016/j.mayocp.2014.01.009. Epub 2014 Apr 3. Mayo Clin Proc. 2014. PMID: 24702733 Free PMC article. Clinical Trial.
Type 2 diabetes mellitus is increasingly diagnosed in obese children and adolescents. ...The significance of the findings from this important trial for the management of youth and young adults with youth-onset type 2 diabetes …
Type 2 diabetes mellitus is increasingly diagnosed in obese children and adolescents. ...The significance of the …
Screening for Prediabetes and Type 2 Diabetes in Children and Adolescents: Evidence Report and Systematic Review for the US Preventive Services Task Force.
Jonas DE, Vander Schaaf EB, Riley S, Allison BA, Middleton JC, Baker C, Ali R, Voisin CE, LeBlanc ES. Jonas DE, et al. JAMA. 2022 Sep 13;328(10):968-979. doi: 10.1001/jama.2022.7957. JAMA. 2022. PMID: 36098720
IMPORTANCE: Of youths diagnosed with type 2 diabetes, many develop microvascular complications by young adulthood. OBJECTIVE: To review the evidence on benefits and harms of screening children and adolescents for prediabetes and type 2 diabet …
IMPORTANCE: Of youths diagnosed with type 2 diabetes, many develop microvascular complications by young adulthood. OBJE …
Healthcare and associated costs related to type 2 diabetes in youth and adolescence: the TODAY clinical trial experience.
Songer TJ, Haymond MW, Glazner JE, Klingensmith GJ, Laffel LM, Zhang P, Hirst K; TODAY Study Group. Songer TJ, et al. Pediatr Diabetes. 2019 Sep;20(6):702-711. doi: 10.1111/pedi.12869. Epub 2019 Jun 6. Pediatr Diabetes. 2019. PMID: 31119838 Free PMC article.
The economic issues related to medical treatments in youth with type 2 diabetes (T2D) are rarely reported and thus not fully understood. The Treatment Options for type 2 Diabetes in Adolescents and Youth clinical trial of yo …
The economic issues related to medical treatments in youth with type 2 diabetes (T2D) are rarely reported and thus not …
59 results