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Hexose/pentose ratio in rhizosphere exudates-mediated soil eutrophic/oligotrophic bacteria regulates the growth pattern of host plant in young apple-aromatic plant intercropping systems.
Zhao M, Sun Y, Dong M, Zhang K, Zhang J, Qin X, Yao Y. Zhao M, et al. Front Microbiol. 2024 Mar 25;15:1364355. doi: 10.3389/fmicb.2024.1364355. eCollection 2024. Front Microbiol. 2024. PMID: 38591033 Free PMC article.
The above- and under-ground biomass of intercrops in TA and TMA were higher than those in TM, with the highest in TA, suggesting that the interspecific competition was the most pronounced in TA. ...Notably, TA caused an increase in pentose content and …
The above- and under-ground biomass of intercrops in TA and TMA were higher than those in TM, with the highest in TA, suggesti …
Compassionate Use Narsoplimab for Severe Refractory Transplantation-Associated Thrombotic Microangiopathy in Children.
Schoettler ML, Patel S, Bryson E, Deeb L, Watkins B, Qayed M, Chandrakasan S, Fitch T, Silvis K, Jones J, Chonat S, Williams KM. Schoettler ML, et al. Transplant Cell Ther. 2024 Mar;30(3):336.e1-336.e8. doi: 10.1016/j.jtct.2023.12.017. Epub 2023 Dec 23. Transplant Cell Ther. 2024. PMID: 38145741
TA-TMA-directed therapy with eculizumab, a complement C5 inhibitor, has resulted in a survival benefit in some studies. However, children with TA-TMA refractory to C5 inhibition with eculizumab (rTA-TMA) have mortality rates exceeding 80%, and there ar
TA-TMA-directed therapy with eculizumab, a complement C5 inhibitor, has resulted in a survival benefit in some studies. Howeve
A prospective multi-institutional study of eculizumab to treat high-risk stem cell transplantation-associated TMA.
Jodele S, Dandoy CE, Aguayo-Hiraldo P, Lane A, Teusink-Cross A, Sabulski A, Mizuno K, Laskin BL, Freedman J, Davies SM. Jodele S, et al. Blood. 2024 Mar 21;143(12):1112-1123. doi: 10.1182/blood.2023022526. Blood. 2024. PMID: 37946262 Clinical Trial.
High-risk, complement mediated, untreated transplant-associated thrombotic microangiopathy (hrTMA) has dismal outcomes due to multi-organ dysfunction syndrome (MODS). The complement C5 blocker eculizumab shows promising results in hrTMA, but has not been prospectively stud …
High-risk, complement mediated, untreated transplant-associated thrombotic microangiopathy (hrTMA) has dismal outcomes due to multi-organ dy …
Characterization of the pleural microenvironment niche and cancer transition using single-cell RNA sequencing in EGFR-mutated lung cancer.
Wu YY, Hsu YL, Huang YC, Su YC, Wu KL, Chang CY, Ong CT, Lai JC, Shen TY, Lee TH, Hung JY, Tsai YM. Wu YY, et al. Theranostics. 2023 Aug 6;13(13):4412-4429. doi: 10.7150/thno.85084. eCollection 2023. Theranostics. 2023. PMID: 37649596 Free PMC article.
Specifically, upregulated complement factors were also found in the MPE, and C5 was associated with poor overall survival in the lung cancer patients with epidermal growth factor receptor mutation. ...
Specifically, upregulated complement factors were also found in the MPE, and C5 was associated with poor overall survival in the lung …
Tracking the Early Stage of Triplet-Induced Photodamage in a DNA Dimer and Oligomer Containing 5-Methylcytosine.
Jin P, Wang JN, Wang X, Jia M, Pan H, Mei Y, Chen J. Jin P, et al. J Phys Chem B. 2023 Aug 10;127(31):6878-6886. doi: 10.1021/acs.jpcb.3c02454. Epub 2023 Jul 25. J Phys Chem B. 2023. PMID: 37490365
Methylation at the C5 position of cytosine, a naturally occurring epigenetic modification on DNA, shows a high correlation with mutational hotspots in disease such as skin cancer. ...Herein, a charge transfer (CT) triplet state, generated via intersystem crossing (ISC) fro …
Methylation at the C5 position of cytosine, a naturally occurring epigenetic modification on DNA, shows a high correlation with mutat …
Super-resolution Ultrasound Microvascular Angiography for Spinal Cord Penumbra Imaging.
Yu J, Dong H, Ta D, Xie R, Xu K. Yu J, et al. Ultrasound Med Biol. 2023 Sep;49(9):2140-2151. doi: 10.1016/j.ultrasmedbio.2023.06.009. Epub 2023 Jul 12. Ultrasound Med Biol. 2023. PMID: 37451953
METHODS: ULM microvasculature imaging was performed on rats with all laminae removed to obtain the blood supply in major spinal cord segments (C5-L5). For adult rats with spinal cord penumbra induced by compression injury (1 s, 10 s and 15 s), ULM imaging was conducted. .. …
METHODS: ULM microvasculature imaging was performed on rats with all laminae removed to obtain the blood supply in major spinal cord segment …
Reductive Hydrogenation of Sulfido-Bridged Tantalum Alkyl Complexes: A Mechanistic Insight.
Carbó JJ, Gómez M, Hernández-Prieto C, Hernán-Gómez A, Martín A, Mena M, Puiggalí-Jou J, Ricart JM, Santamaría C. Carbó JJ, et al. Inorg Chem. 2023 Jul 3;62(26):10100-10109. doi: 10.1021/acs.inorgchem.3c00043. Epub 2023 Jun 15. Inorg Chem. 2023. PMID: 37319404 Free PMC article.
Hydrogenolysis of a series of alkyl sulfido-bridged tantalum(IV) dinuclear complexes [Ta(eta(5)-C(5)Me(5))R(mu-S)](2) [R = Me, nBu (1), Et, CH(2)SiMe(3), C(3)H(5), Ph, CH(2)Ph (2), p-MeC(6)H(4)CH(2) (3)] has led quantitatively to the Ta(III) tetrametallic sulfide cl …
Hydrogenolysis of a series of alkyl sulfido-bridged tantalum(IV) dinuclear complexes [Ta(eta(5)-C(5)Me(5))R(mu-S)](2) [R = Me, nBu (1 …
Application of a scoring system in Japanese patients diagnosed with atypical hemolytic uremic syndrome to assess the relationship between the score and clinical responses to eculizumab.
Wada H, Teranishi H, Shimono A, Kato N, Maruyama S, Matsumoto M. Wada H, et al. Thromb J. 2023 Apr 18;21(1):43. doi: 10.1186/s12959-023-00489-0. Thromb J. 2023. PMID: 37072821 Free PMC article.
The TMA/aHUS score system could become a supporting tool for the clinical diagnosis of aHUS and probability of response to treatment with a C5 inhibitor. TRIAL REGISTRATION: This study was conducted as per good PMS practice guidelines for drugs (MHLW Ministerial Ordinance …
The TMA/aHUS score system could become a supporting tool for the clinical diagnosis of aHUS and probability of response to treatment with a …
160 results