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Bone morphogenetic protein 7 is elevated in patients with chronic liver disease and exerts fibrogenic effects on human hepatic stellate cells.
Tacke F, Gäbele E, Bataille F, Schwabe RF, Hellerbrand C, Klebl F, Straub RH, Luedde T, Manns MP, Trautwein C, Brenner DA, Schölmerich J, Schnabl B. Tacke F, et al. Dig Dis Sci. 2007 Dec;52(12):3404-15. doi: 10.1007/s10620-007-9758-8. Epub 2007 Apr 6. Dig Dis Sci. 2007. PMID: 17415633
Up-regulated eotaxin plasma levels in chronic liver disease patients indicate hepatic inflammation, advanced fibrosis and adverse clinical course.
Tacke F, Trautwein C, Yagmur E, Hellerbrand C, Wiest R, Brenner DA, Schnabl B. Tacke F, et al. J Gastroenterol Hepatol. 2007 Aug;22(8):1256-64. doi: 10.1111/j.1440-1746.2006.04621.x. J Gastroenterol Hepatol. 2007. PMID: 17688666
Inflammatory pathways in liver homeostasis and liver injury.
Tacke F, Luedde T, Trautwein C. Tacke F, et al. Clin Rev Allergy Immunol. 2009 Feb;36(1):4-12. doi: 10.1007/s12016-008-8091-0. Clin Rev Allergy Immunol. 2009. PMID: 18600481 Review.
Chemokine-directed immune cell infiltration in acute and chronic liver disease.
Karlmark KR, Wasmuth HE, Trautwein C, Tacke F. Karlmark KR, et al. Expert Rev Gastroenterol Hepatol. 2008 Apr;2(2):233-42. doi: 10.1586/17474124.2.2.233. Expert Rev Gastroenterol Hepatol. 2008. PMID: 19072358 Review.
Monocytes and macrophages as cellular targets in liver fibrosis.
Heymann F, Trautwein C, Tacke F. Heymann F, et al. Inflamm Allergy Drug Targets. 2009 Sep;8(4):307-18. doi: 10.2174/187152809789352230. Inflamm Allergy Drug Targets. 2009. PMID: 19534673 Review.
Hepatic recruitment of the inflammatory Gr1+ monocyte subset upon liver injury promotes hepatic fibrosis.
Karlmark KR, Weiskirchen R, Zimmermann HW, Gassler N, Ginhoux F, Weber C, Merad M, Luedde T, Trautwein C, Tacke F. Karlmark KR, et al. Hepatology. 2009 Jul;50(1):261-74. doi: 10.1002/hep.22950. Hepatology. 2009. PMID: 19554540
The chemokine scavenging receptor D6 limits acute toxic liver injury in vivo.
Berres ML, Trautwein C, Zaldivar MM, Schmitz P, Pauels K, Lira SA, Tacke F, Wasmuth HE. Berres ML, et al. Biol Chem. 2009 Oct;390(10):1039-45. doi: 10.1515/BC.2009.119. Biol Chem. 2009. PMID: 19642876
Analysis of antigen-presenting functionality of cultured rat hepatic stellate cells and transdifferentiated myofibroblasts.
Bomble M, Tacke F, Rink L, Kovalenko E, Weiskirchen R. Bomble M, et al. Biochem Biophys Res Commun. 2010 May 28;396(2):342-7. doi: 10.1016/j.bbrc.2010.04.094. Epub 2010 Apr 18. Biochem Biophys Res Commun. 2010. PMID: 20403338
TAK1 suppresses a NEMO-dependent but NF-kappaB-independent pathway to liver cancer.
Bettermann K, Vucur M, Haybaeck J, Koppe C, Janssen J, Heymann F, Weber A, Weiskirchen R, Liedtke C, Gassler N, Müller M, de Vos R, Wolf MJ, Boege Y, Seleznik GM, Zeller N, Erny D, Fuchs T, Zoller S, Cairo S, Buendia MA, Prinz M, Akira S, Tacke F, Heikenwalder M, Trautwein C, Luedde T. Bettermann K, et al. Cancer Cell. 2010 May 18;17(5):481-96. doi: 10.1016/j.ccr.2010.03.021. Cancer Cell. 2010. PMID: 20478530
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