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Mechanisms of hepatic very low-density lipoprotein overproduction in insulin resistance.
Adeli K, Taghibiglou C, Van Iderstine SC, Lewis GF. Adeli K, et al. Among authors: taghibiglou c. Trends Cardiovasc Med. 2001 Jul;11(5):170-6. doi: 10.1016/s1050-1738(01)00084-6. Trends Cardiovasc Med. 2001. PMID: 11597827 Review.
Mechanisms involved in cholesterol-induced neuronal insulin resistance.
Taghibiglou C, Bradley CA, Gaertner T, Li Y, Wang Y, Wang YT. Taghibiglou C, et al. Neuropharmacology. 2009 Sep;57(3):268-76. doi: 10.1016/j.neuropharm.2009.05.013. Epub 2009 Jun 10. Neuropharmacology. 2009. PMID: 19523477
A biochemical and functional characterization of diet-induced brain insulin resistance.
Mielke JG, Taghibiglou C, Liu L, Zhang Y, Jia Z, Adeli K, Wang YT. Mielke JG, et al. Among authors: taghibiglou c. J Neurochem. 2005 Jun;93(6):1568-78. doi: 10.1111/j.1471-4159.2005.03155.x. J Neurochem. 2005. PMID: 15935073
Oleate-mediated stimulation of microsomal triglyceride transfer protein (MTP) gene promoter: implications for hepatic MTP overexpression in insulin resistance.
Qiu W, Taghibiglou C, Avramoglu RK, Van Iderstine SC, Naples M, Ashrafpour H, Mhapsekar S, Sato R, Adeli K. Qiu W, et al. Among authors: taghibiglou c. Biochemistry. 2005 Mar 1;44(8):3041-9. doi: 10.1021/bi047803+. Biochemistry. 2005. PMID: 15723548
Ameliorated hepatic insulin resistance is associated with normalization of microsomal triglyceride transfer protein expression and reduction in very low density lipoprotein assembly and secretion in the fructose-fed hamster.
Carpentier A, Taghibiglou C, Leung N, Szeto L, Van Iderstine SC, Uffelman KD, Buckingham R, Adeli K, Lewis GF. Carpentier A, et al. Among authors: taghibiglou c. J Biol Chem. 2002 Aug 9;277(32):28795-802. doi: 10.1074/jbc.M204568200. Epub 2002 Jun 4. J Biol Chem. 2002. PMID: 12048212
Simvastatin, an HMG-CoA reductase inhibitor, induces the synthesis and secretion of apolipoprotein AI in HepG2 cells and primary hamster hepatocytes.
Bonn V, Cheung RC, Chen B, Taghibiglou C, Van Iderstine SC, Adeli K. Bonn V, et al. Among authors: taghibiglou c. Atherosclerosis. 2002 Jul;163(1):59-68. doi: 10.1016/s0021-9150(01)00754-7. Atherosclerosis. 2002. PMID: 12048122
Treatment with atorvastatin ameliorates hepatic very-low-density lipoprotein overproduction in an animal model of insulin resistance, the fructose-fed Syrian golden hamster: evidence that reduced hypertriglyceridemia is accompanied by improved hepatic insulin sensitivity.
Mangaloglu L, Cheung RC, Van Iderstine SC, Taghibiglou C, Pontrelli L, Adeli K. Mangaloglu L, et al. Among authors: taghibiglou c. Metabolism. 2002 Apr;51(4):409-18. doi: 10.1053/meta.2002.30954. Metabolism. 2002. PMID: 11912545
Hepatic very low density lipoprotein-ApoB overproduction is associated with attenuated hepatic insulin signaling and overexpression of protein-tyrosine phosphatase 1B in a fructose-fed hamster model of insulin resistance.
Taghibiglou C, Rashid-Kolvear F, Van Iderstine SC, Le-Tien H, Fantus IG, Lewis GF, Adeli K. Taghibiglou C, et al. J Biol Chem. 2002 Jan 4;277(1):793-803. doi: 10.1074/jbc.M106737200. Epub 2001 Oct 11. J Biol Chem. 2002. PMID: 11598116
Intracellular mechanisms mediating the inhibition of apoB-containing lipoprotein synthesis and secretion in HepG2 cells by avasimibe (CI-1011), a novel acyl-coenzyme A: cholesterol acyltransferase (ACAT) inhibitor.
Taghibiglou C, Van Iderstine SC, Kulinski A, Rudy D, Adeli K. Taghibiglou C, et al. Biochem Pharmacol. 2002 Feb 1;63(3):349-60. doi: 10.1016/s0006-2952(01)00918-2. Biochem Pharmacol. 2002. PMID: 11853686
Down regulation of brain cellular prion protein in an animal model of insulin resistance: possible implication in increased prevalence of stroke in pre-diabetics/diabetics.
Pham N, Dhar A, Khalaj S, Desai K, Taghibiglou C. Pham N, et al. Among authors: taghibiglou c. Biochem Biophys Res Commun. 2014 May 30;448(2):151-6. doi: 10.1016/j.bbrc.2014.04.071. Epub 2014 Apr 26. Biochem Biophys Res Commun. 2014. PMID: 24780399
Since one of the physiological functions of the cellular prion protein (PrP(C)) is neuroprotection, we studied effects of brain insulin resistance on the expression of PrP(C) in fructose-fed rats as an animal model of prediabetes. ...Considering a neuroprotective ro …
Since one of the physiological functions of the cellular prion protein (PrP(C)) is neuroprotection, we studied effects of brain insul …
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