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386 results

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Discovery of a novel class of potent human deoxyuridine triphosphatase inhibitors remarkably enhancing the antitumor activity of thymidylate synthase inhibitors.
Miyahara S, Miyakoshi H, Yokogawa T, Chong KT, Taguchi J, Muto T, Endoh K, Yano W, Wakasa T, Ueno H, Takao Y, Fujioka A, Hashimoto A, Itou K, Yamamura K, Nomura M, Nagasawa H, Shuto S, Fukuoka M. Miyahara S, et al. Among authors: taguchi j. J Med Chem. 2012 Apr 12;55(7):2970-80. doi: 10.1021/jm201628y. Epub 2012 Mar 26. J Med Chem. 2012. PMID: 22339362
Synthesis and discovery of N-carbonylpyrrolidine- or N-sulfonylpyrrolidine-containing uracil derivatives as potent human deoxyuridine triphosphatase inhibitors.
Miyakoshi H, Miyahara S, Yokogawa T, Chong KT, Taguchi J, Endoh K, Yano W, Wakasa T, Ueno H, Takao Y, Nomura M, Shuto S, Nagasawa H, Fukuoka M. Miyakoshi H, et al. Among authors: taguchi j. J Med Chem. 2012 Apr 12;55(7):2960-9. doi: 10.1021/jm201627n. Epub 2012 Mar 26. J Med Chem. 2012. PMID: 22404301
Discovery of highly potent human deoxyuridine triphosphatase inhibitors based on the conformation restriction strategy.
Miyahara S, Miyakoshi H, Yokogawa T, Chong KT, Taguchi J, Muto T, Endoh K, Yano W, Wakasa T, Ueno H, Takao Y, Fujioka A, Hashimoto A, Itou K, Yamamura K, Nomura M, Nagasawa H, Shuto S, Fukuoka M. Miyahara S, et al. Among authors: taguchi j. J Med Chem. 2012 Jun 14;55(11):5483-96. doi: 10.1021/jm300416h. Epub 2012 May 30. J Med Chem. 2012. PMID: 22607122
1,2,3-Triazole-containing uracil derivatives with excellent pharmacokinetics as a novel class of potent human deoxyuridine triphosphatase inhibitors.
Miyakoshi H, Miyahara S, Yokogawa T, Endoh K, Muto T, Yano W, Wakasa T, Ueno H, Chong KT, Taguchi J, Nomura M, Takao Y, Fujioka A, Hashimoto A, Itou K, Yamamura K, Shuto S, Nagasawa H, Fukuoka M. Miyakoshi H, et al. Among authors: taguchi j. J Med Chem. 2012 Jul 26;55(14):6427-37. doi: 10.1021/jm3004174. Epub 2012 Jul 3. J Med Chem. 2012. PMID: 22715973
TAS-114, a First-in-Class Dual dUTPase/DPD Inhibitor, Demonstrates Potential to Improve Therapeutic Efficacy of Fluoropyrimidine-Based Chemotherapy.
Yano W, Yokogawa T, Wakasa T, Yamamura K, Fujioka A, Yoshisue K, Matsushima E, Miyahara S, Miyakoshi H, Taguchi J, Chong KT, Takao Y, Fukuoka M, Matsuo K. Yano W, et al. Among authors: taguchi j. Mol Cancer Ther. 2018 Aug;17(8):1683-1693. doi: 10.1158/1535-7163.MCT-17-0911. Epub 2018 May 10. Mol Cancer Ther. 2018. PMID: 29748212
Retrospective analysis of percutaneous intervention of the renal artery in transplanted kidneys in children and adolescents at a tertiary public hospital.
Faccinetto ACB, Santos GRF, Taguchi JC, Orellana HC, Galhardo A, Kanhouche G, Barteczko MLM, Tedesco Júnior H, Bravo-Valenzuela NJM, Moises VA, Pestana JOM, Silva CMC, Barbosa AHP. Faccinetto ACB, et al. Among authors: taguchi jc. PLoS One. 2024 Mar 29;19(3):e0297975. doi: 10.1371/journal.pone.0297975. eCollection 2024. PLoS One. 2024. PMID: 38551934 Free PMC article.
Impact of adaptive radiotherapy on survival in locally advanced nasopharyngeal carcinoma treated with concurrent chemoradiotherapy.
Uchinami Y, Yasuda K, Minatogawa H, Dekura Y, Nishikawa N, Kinoshita R, Nishioka K, Katoh N, Mori T, Otsuka M, Miyamoto N, Suzuki R, Kobashi K, Shimizu Y, Taguchi J, Tsushima N, Kano S, Homma A, Aoyama H. Uchinami Y, et al. Among authors: taguchi j. Radiat Oncol J. 2024 Mar;42(1):74-82. doi: 10.3857/roj.2023.00374. Epub 2024 Mar 18. Radiat Oncol J. 2024. PMID: 38549386 Free PMC article.
386 results