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HSP90 at the hub of protein homeostasis: emerging mechanistic insights.
Taipale M, Jarosz DF, Lindquist S. Taipale M, et al. Nat Rev Mol Cell Biol. 2010 Jul;11(7):515-28. doi: 10.1038/nrm2918. Epub 2010 Jun 9. Nat Rev Mol Cell Biol. 2010. PMID: 20531426 Review.
Protein homeostasis and the phenotypic manifestation of genetic diversity: principles and mechanisms.
Jarosz DF, Taipale M, Lindquist S. Jarosz DF, et al. Among authors: taipale m. Annu Rev Genet. 2010;44:189-216. doi: 10.1146/annurev.genet.40.110405.090412. Annu Rev Genet. 2010. PMID: 21047258 Review.
Quantitative analysis of HSP90-client interactions reveals principles of substrate recognition.
Taipale M, Krykbaeva I, Koeva M, Kayatekin C, Westover KD, Karras GI, Lindquist S. Taipale M, et al. Cell. 2012 Aug 31;150(5):987-1001. doi: 10.1016/j.cell.2012.06.047. Cell. 2012. PMID: 22939624 Free PMC article.
Widespread regulation of translation by elongation pausing in heat shock.
Shalgi R, Hurt JA, Krykbaeva I, Taipale M, Lindquist S, Burge CB. Shalgi R, et al. Among authors: taipale m. Mol Cell. 2013 Feb 7;49(3):439-52. doi: 10.1016/j.molcel.2012.11.028. Epub 2013 Jan 3. Mol Cell. 2013. PMID: 23290915 Free PMC article.
Chaperones as thermodynamic sensors of drug-target interactions reveal kinase inhibitor specificities in living cells.
Taipale M, Krykbaeva I, Whitesell L, Santagata S, Zhang J, Liu Q, Gray NS, Lindquist S. Taipale M, et al. Nat Biotechnol. 2013 Jul;31(7):630-7. doi: 10.1038/nbt.2620. Epub 2013 Jun 30. Nat Biotechnol. 2013. PMID: 23811600 Free PMC article.
The mammalian-membrane two-hybrid assay (MaMTH) for probing membrane-protein interactions in human cells.
Petschnigg J, Groisman B, Kotlyar M, Taipale M, Zheng Y, Kurat CF, Sayad A, Sierra JR, Mattiazzi Usaj M, Snider J, Nachman A, Krykbaeva I, Tsao MS, Moffat J, Pawson T, Lindquist S, Jurisica I, Stagljar I. Petschnigg J, et al. Among authors: taipale m. Nat Methods. 2014 May;11(5):585-92. doi: 10.1038/nmeth.2895. Epub 2014 Mar 23. Nat Methods. 2014. PMID: 24658140
Genome-wide prediction and validation of peptides that bind human prosurvival Bcl-2 proteins.
DeBartolo J, Taipale M, Keating AE. DeBartolo J, et al. Among authors: taipale m. PLoS Comput Biol. 2014 Jun 26;10(6):e1003693. doi: 10.1371/journal.pcbi.1003693. eCollection 2014 Jun. PLoS Comput Biol. 2014. PMID: 24967846 Free PMC article.
A quantitative chaperone interaction network reveals the architecture of cellular protein homeostasis pathways.
Taipale M, Tucker G, Peng J, Krykbaeva I, Lin ZY, Larsen B, Choi H, Berger B, Gingras AC, Lindquist S. Taipale M, et al. Cell. 2014 Jul 17;158(2):434-448. doi: 10.1016/j.cell.2014.05.039. Cell. 2014. PMID: 25036637 Free PMC article.
Widespread macromolecular interaction perturbations in human genetic disorders.
Sahni N, Yi S, Taipale M, Fuxman Bass JI, Coulombe-Huntington J, Yang F, Peng J, Weile J, Karras GI, Wang Y, Kovács IA, Kamburov A, Krykbaeva I, Lam MH, Tucker G, Khurana V, Sharma A, Liu YY, Yachie N, Zhong Q, Shen Y, Palagi A, San-Miguel A, Fan C, Balcha D, Dricot A, Jordan DM, Walsh JM, Shah AA, Yang X, Stoyanova AK, Leighton A, Calderwood MA, Jacob Y, Cusick ME, Salehi-Ashtiani K, Whitesell LJ, Sunyaev S, Berger B, Barabási AL, Charloteaux B, Hill DE, Hao T, Roth FP, Xia Y, Walhout AJM, Lindquist S, Vidal M. Sahni N, et al. Among authors: taipale m. Cell. 2015 Apr 23;161(3):647-660. doi: 10.1016/j.cell.2015.04.013. Cell. 2015. PMID: 25910212 Free PMC article.
An inter-species protein-protein interaction network across vast evolutionary distance.
Zhong Q, Pevzner SJ, Hao T, Wang Y, Mosca R, Menche J, Taipale M, Taşan M, Fan C, Yang X, Haley P, Murray RR, Mer F, Gebreab F, Tam S, MacWilliams A, Dricot A, Reichert P, Santhanam B, Ghamsari L, Calderwood MA, Rolland T, Charloteaux B, Lindquist S, Barabási AL, Hill DE, Aloy P, Cusick ME, Xia Y, Roth FP, Vidal M. Zhong Q, et al. Among authors: taipale m. Mol Syst Biol. 2016 Apr 22;12(4):865. doi: 10.15252/msb.20156484. Mol Syst Biol. 2016. PMID: 27107014 Free PMC article.
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