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Targeting all transforming growth factor-β isoforms with an Fc chimeric receptor impairs tumor growth and angiogenesis of oral squamous cell cancer.
Takahashi K, Akatsu Y, Podyma-Inoue KA, Matsumoto T, Takahashi H, Yoshimatsu Y, Koinuma D, Shirouzu M, Miyazono K, Watabe T. Takahashi K, et al. Among authors: takahashi h. J Biol Chem. 2020 Sep 4;295(36):12559-12572. doi: 10.1074/jbc.RA120.012492. Epub 2020 Jul 6. J Biol Chem. 2020. PMID: 32631954 Free PMC article.
Interleukin-13 receptor α2 is a novel marker and potential therapeutic target for human melanoma.
Okamoto H, Yoshimatsu Y, Tomizawa T, Kunita A, Takayama R, Morikawa T, Komura D, Takahashi K, Oshima T, Sato M, Komai M, Podyma-Inoue KA, Uchida H, Hamada H, Fujiu K, Ishikawa S, Fukayama M, Fukuhara T, Watabe T. Okamoto H, et al. Among authors: takahashi k. Sci Rep. 2019 Feb 4;9(1):1281. doi: 10.1038/s41598-019-39018-3. Sci Rep. 2019. PMID: 30718742 Free PMC article.
TGF-β generates a population of cancer cells residing in G1 phase with high motility and metastatic potential via KRTAP2-3.
Takahashi K, Podyma-Inoue KA, Saito M, Sakakitani S, Sugauchi A, Iida K, Iwabuchi S, Koinuma D, Kurioka K, Konishi T, Tanaka S, Kaida A, Miura M, Hashimoto S, Okada M, Uchihashi T, Miyazono K, Watabe T. Takahashi K, et al. Cell Rep. 2022 Sep 27;40(13):111411. doi: 10.1016/j.celrep.2022.111411. Cell Rep. 2022. PMID: 36170816 Free article.
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