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Involvement of prostaglandin E receptor subtype EP(4) in colon carcinogenesis.
Mutoh M, Watanabe K, Kitamura T, Shoji Y, Takahashi M, Kawamori T, Tani K, Kobayashi M, Maruyama T, Kobayashi K, Ohuchida S, Sugimoto Y, Narumiya S, Sugimura T, Wakabayashi K. Mutoh M, et al. Among authors: takahashi m. Cancer Res. 2002 Jan 1;62(1):28-32. Cancer Res. 2002. PMID: 11782353
Colonic adenocarcinomas rapidly induced by the combined treatment with 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine and dextran sodium sulfate in male ICR mice possess beta-catenin gene mutations and increases immunoreactivity for beta-catenin, cyclooxygenase-2 and inducible nitric oxide synthase.
Tanaka T, Suzuki R, Kohno H, Sugie S, Takahashi M, Wakabayashi K. Tanaka T, et al. Among authors: takahashi m. Carcinogenesis. 2005 Jan;26(1):229-38. doi: 10.1093/carcin/bgh292. Epub 2004 Sep 30. Carcinogenesis. 2005. PMID: 15459021
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