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Marked strain differences in the pharmacokinetics of an alpha4beta1 integrin antagonist, 4-[1-[3-Chloro-4-[N-(2-methylphenyl)-ureido]phenylacetyl]-(4S)-fluoro-(2S)-pyrrolidine-2-yl]-methoxybenzoic Acid (D01-4582), in Sprague-Dawley rats are associated with albumin genetic polymorphism.
Ito T, Takahashi M, Sudo K, Sugiyama Y. Ito T, et al. Among authors: takahashi m. J Pharmacol Exp Ther. 2007 Jan;320(1):124-32. doi: 10.1124/jpet.106.111948. Epub 2006 Oct 12. J Pharmacol Exp Ther. 2007. PMID: 17038508
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