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Page 1
Intrinsic Immunogenicity of Small Cell Lung Carcinoma Revealed by Its Cellular Plasticity.
Mahadevan NR, Knelson EH, Wolff JO, Vajdi A, Saigí M, Campisi M, Hong D, Thai TC, Piel B, Han S, Reinhold BB, Duke-Cohan JS, Poitras MJ, Taus LJ, Lizotte PH, Portell A, Quadros V, Santucci AD, Murayama T, Cañadas I, Kitajima S, Akitsu A, Fridrikh M, Watanabe H, Reardon B, Gokhale PC, Paweletz CP, Awad MM, Van Allen EM, Lako A, Wang XT, Chen B, Hong F, Sholl LM, Tolstorukov MY, Pfaff K, Jänne PA, Gjini E, Edwards R, Rodig S, Reinherz EL, Oser MG, Barbie DA. Mahadevan NR, et al. Among authors: murayama t. Cancer Discov. 2021 Aug;11(8):1952-1969. doi: 10.1158/2159-8290.CD-20-0913. Epub 2021 Mar 11. Cancer Discov. 2021. PMID: 33707236 Free PMC article.
RNA sensing induced by chromosome missegregation augments anti-tumor immunity.
Sasaki N, Homme M, Murayama T, Osaki T, Tenma T, An T, Takegami Y, Tani T, Gedeon PC, Kobayashi Y, Cañadas I, Barbie DA, Yao R, Kitajima S. Sasaki N, et al. Among authors: murayama t. Mol Cell. 2025 Feb 20;85(4):770-786.e7. doi: 10.1016/j.molcel.2024.11.025. Epub 2024 Dec 19. Mol Cell. 2025. PMID: 39706184 Free PMC article.
Targeting TREX1 Induces Innate Immune Response in Drug-Resistant Small-Cell Lung Cancer.
Murayama T, Mahadevan NR, Meador CB, Ivanova EV, Pan Y, Knelson EH, Tani T, Nakayama J, Ma X, Thai TC, Hung YP, Kim W, Watanabe H, Cai KQ, Hata AN, Paweletz CP, Barbie DA, Cañadas I. Murayama T, et al. Cancer Res Commun. 2024 Sep 1;4(9):2399-2414. doi: 10.1158/2767-9764.CRC-24-0360. Cancer Res Commun. 2024. PMID: 39177280 Free PMC article.
The membrane-linked adaptor FRS2β fashions a cytokine-rich inflammatory microenvironment that promotes breast cancer carcinogenesis.
Takeuchi Y, Kimura N, Murayama T, Machida Y, Iejima D, Nishimura T, Terashima M, Wang Y, Li M, Sakamoto R, Yamamoto M, Itano N, Inoue Y, Ito M, Yoshida N, Inoue JI, Akashi K, Saya H, Fujita K, Kuroda M, Kitabayashi I, Voon D, Suzuki T, Tojo A, Gotoh N. Takeuchi Y, et al. Among authors: murayama t. Proc Natl Acad Sci U S A. 2021 Oct 26;118(43):e2103658118. doi: 10.1073/pnas.2103658118. Proc Natl Acad Sci U S A. 2021. PMID: 34663724 Free PMC article.
MCM10 compensates for Myc-induced DNA replication stress in breast cancer stem-like cells.
Murayama T, Takeuchi Y, Yamawaki K, Natsume T, Li M, Marcela RN, Nishimura T, Kogure Y, Nakata A, Tominaga K, Sasahara A, Yano M, Ishikawa S, Ohta T, Ikeda K, Horie-Inoue K, Inoue S, Seki M, Suzuki Y, Sugano S, Enomoto T, Tanabe M, Tada KI, Kanemaki MT, Okamoto K, Tojo A, Gotoh N. Murayama T, et al. Cancer Sci. 2021 Mar;112(3):1209-1224. doi: 10.1111/cas.14776. Epub 2021 Jan 22. Cancer Sci. 2021. PMID: 33340428 Free PMC article.
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