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The Prediction of the Relative Importance of CYP3A/P-glycoprotein to the Nonlinear Intestinal Absorption of Drugs by Advanced Compartmental Absorption and Transit Model.
Takano J, Maeda K, Bolger MB, Sugiyama Y. Takano J, et al. Drug Metab Dispos. 2016 Nov;44(11):1808-1818. doi: 10.1124/dmd.116.070011. Epub 2016 Aug 18. Drug Metab Dispos. 2016. PMID: 27538919
Predicting drug-drug interactions involving the inhibition of intestinal CYP3A4 and P-glycoprotein.
Tachibana T, Kato M, Takano J, Sugiyama Y. Tachibana T, et al. Among authors: takano j. Curr Drug Metab. 2010 Nov;11(9):762-77. doi: 10.2174/138920010794328922. Curr Drug Metab. 2010. PMID: 21189139 Review.
Organic Anion Transporting Polypeptide 1a4 is Responsible for the Hepatic Uptake of Cardiac Glycosides in Mice.
Takano J, Maeda K, Kusuhara H, Sugiyama Y. Takano J, et al. Drug Metab Dispos. 2018 May;46(5):652-657. doi: 10.1124/dmd.117.079483. Epub 2018 Jan 18. Drug Metab Dispos. 2018. PMID: 29348124
Nonlinear pharmacokinetics of oral quinidine and verapamil in healthy subjects: a clinical microdosing study.
Maeda K, Takano J, Ikeda Y, Fujita T, Oyama Y, Nozawa K, Kumagai Y, Sugiyama Y. Maeda K, et al. Among authors: takano j. Clin Pharmacol Ther. 2011 Aug;90(2):263-70. doi: 10.1038/clpt.2011.108. Epub 2011 Jun 29. Clin Pharmacol Ther. 2011. PMID: 21716273 Clinical Trial.
Radiosynthesis of novel pitavastatin derivative ([18 F]PTV-F1) as a tracer for hepatic OATP using a one-pot synthetic procedure.
Kimura H, Yagi Y, Arimitsu K, Maeda K, Ikejiri K, Takano JI, Kusuhara H, Kagawa S, Ono M, Sugiyama Y, Saji H. Kimura H, et al. J Labelled Comp Radiopharm. 2016 Nov;59(13):565-575. doi: 10.1002/jlcr.3464. Epub 2016 Oct 2. J Labelled Comp Radiopharm. 2016. PMID: 27696476
Direct and rapid genotyping of SLCO1B1 388A>G and 521T>C in human blood specimens using the SmartAmp-2 method.
Yoshida K, Takano J, Ishizu Y, Lezhava A, Ieiri I, Maeda K, Hayashizaki Y, Sugiyama Y. Yoshida K, et al. Among authors: takano j. AAPS J. 2013 Apr;15(2):618-22. doi: 10.1208/s12248-013-9471-9. Epub 2013 Mar 8. AAPS J. 2013. PMID: 23471819 Free PMC article.
Quantitative prediction of in vivo drug interactions between nevirapine and antifungal agents from in vitro data in rats.
Kishimoto W, Takano J, Senda C, Ishiguro N, Sakai K, Igarashi T. Kishimoto W, et al. Among authors: takano j. Biol Pharm Bull. 2000 Sep;23(9):1027-32. doi: 10.1248/bpb.23.1027. Biol Pharm Bull. 2000. PMID: 10993198
In Vitro Mechanistic Study of the Distribution of Lascufloxacin into Epithelial Lining Fluid.
Ohya K, Takano J, Manita S. Ohya K, et al. Among authors: takano j. Antimicrob Agents Chemother. 2019 Mar 27;63(4):e02208-18. doi: 10.1128/AAC.02208-18. Print 2019 Apr. Antimicrob Agents Chemother. 2019. PMID: 30718243 Free PMC article.
Development of pH-Independent Drug Release Formulation Using Lipocalin-Type Prostaglandin D Synthase.
Mizoguchi M, Nakatsuji M, Takano J, Ishibashi O, Wada K, Inui T. Mizoguchi M, et al. Among authors: takano j. J Pharm Sci. 2016 Sep;105(9):2735-2742. doi: 10.1016/S0022-3549(15)00176-8. Epub 2016 Jan 25. J Pharm Sci. 2016. PMID: 26886322
Tocilizumab, a humanized anti-IL-6R antibody, as an emerging therapeutic option for rheumatoid arthritis: molecular and cellular mechanistic insights.
Hashizume M, Tan SL, Takano J, Ohsawa K, Hasada I, Hanasaki A, Ito I, Mihara M, Nishida K. Hashizume M, et al. Among authors: takano j. Int Rev Immunol. 2015 May;34(3):265-79. doi: 10.3109/08830185.2014.938325. Epub 2014 Aug 6. Int Rev Immunol. 2015. PMID: 25099958 Review.
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