Takasaki W - Search Results

1

Species differences in enantioselective 2-oxidations of RS-8359, a selective and reversible MAO-A inhibitor, and cinchona alkaloids by aldehyde oxidase.

Itoh K, Yamamura M, Takasaki W, Sasaki T, Masubuchi A, Tanaka Y. Itoh K, et al. Among authors: takasaki w. Biopharm Drug Dispos. 2006 Apr;27(3):133-9. doi: 10.1002/bdd.494. Biopharm Drug Dispos. 2006. PMID: 16400710

2

Enantioselective 2-hydroxylation of RS-8359, a selective and reversible MAO-A inhibitor, by cytochrome P450 in mouse and rat liver microsomes.

Itoh K, Nishiya Y, Takasaki W, Adachi M, Tanaka Y. Itoh K, et al. Among authors: takasaki w. Chirality. 2006 Aug;18(8):592-8. doi: 10.1002/chir.20291. Chirality. 2006. PMID: 16642492

3

Stereoselective pharmacokinetics of RS-8359, a selective and reversible MAO-A inhibitor, by species-dependent drug-metabolizing enzymes.

Takasaki W, Yamamura M, Nozaki A, Nitanai T, Sasahara K, Itoh K, Tanaka Y. Takasaki W, et al. Chirality. 2005 Mar;17(3):135-41. doi: 10.1002/chir.20124. Chirality. 2005. PMID: 15704197

4

Stereoselective pharmacokinetics of RS-8359, a selective and reversible inhibitor of A-type monoamine oxidase, in rats, mice, dogs, and monkeys.

Takasaki W, Yamamura M, Shigehara E, Suzuki Y, Tonohiro T, Hara T, Tanaka Y. Takasaki W, et al. Biol Pharm Bull. 1999 May;22(5):498-503. doi: 10.1248/bpb.22.498. Biol Pharm Bull. 1999. PMID: 10375171

5

Generation and functional characterization of mice with a disrupted glutathione S-transferase, theta 1 gene.

Fujimoto K, Arakawa S, Watanabe T, Yasumo H, Ando Y, Takasaki W, Manabe S, Yamoto T, Oda S. Fujimoto K, et al. Among authors: takasaki w. Drug Metab Dispos. 2007 Dec;35(12):2196-202. doi: 10.1124/dmd.107.017905. Epub 2007 Sep 7. Drug Metab Dispos. 2007. PMID: 17827337

6

Characterization of phenotypes in Gstm1-null mice by cytosolic and in vivo metabolic studies using 1,2-dichloro-4-nitrobenzene.

Fujimoto K, Arakawa S, Shibaya Y, Miida H, Ando Y, Yasumo H, Hara A, Uchiyama M, Iwabuchi H, Takasaki W, Manabe S, Yamoto T. Fujimoto K, et al. Among authors: takasaki w. Drug Metab Dispos. 2006 Sep;34(9):1495-501. doi: 10.1124/dmd.106.010009. Epub 2006 Jun 7. Drug Metab Dispos. 2006. PMID: 16760226

7

A comparison of the effects of 3-hydroxy-3-methylglutaryl-coenzyme a (HMG-CoA) reductase inhibitors on the CYP3A4-dependent oxidation of mexazolam in vitro.

Ishigami M, Honda T, Takasaki W, Ikeda T, Komai T, Ito K, Sugiyama Y. Ishigami M, et al. Among authors: takasaki w. Drug Metab Dispos. 2001 Mar;29(3):282-8. Drug Metab Dispos. 2001. PMID: 11181496

8

Characterization of UDP-glucuronosyltransferases (UGTS) involved in the metabolism of troglitazone in rats and humans.

Yoshigae Y, Konno K, Takasaki W, Ikeda T. Yoshigae Y, et al. Among authors: takasaki w. J Toxicol Sci. 2000 Dec;25(5):433-41. doi: 10.2131/jts.25.5_433. J Toxicol Sci. 2000. PMID: 11201174

9

Highly frequent anti-idiotype antibody in cynomolgus monkeys developed against mouse-derived regions of anti-Fas antibody humanized by complementarity determining region grafting.

Saito-Yabe M, Yoshigae Y, Takasaki W, Kurihara A, Ikeda T, Okazaki O. Saito-Yabe M, et al. Among authors: takasaki w. Br J Pharmacol. 2009 Sep;158(2):548-57. doi: 10.1111/j.1476-5381.2009.00326.x. Epub 2009 Jul 23. Br J Pharmacol. 2009. PMID: 19645714 Free PMC article.

10

Stereoselective determination of the active metabolites of a new anti-inflammatory agent (CS-670) in human and rat plasma using antibody-mediated extraction and high-performance liquid chromatography.

Takasaki W, Asami M, Muramatsu S, Hayashi R, Tanaka Y, Kawabata K, Hoshiyama K. Takasaki W, et al. J Chromatogr. 1993 Mar 5;613(1):67-77. doi: 10.1016/0378-4347(93)80198-d. J Chromatogr. 1993. PMID: 8458904

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