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MKC-231, a choline uptake enhancer: (2) Effect on synthesis and release of acetylcholine in AF64A-treated rats.
Takashina K, Bessho T, Mori R, Eguchi J, Saito K. Takashina K, et al. J Neural Transm (Vienna). 2008 Jul;115(7):1027-35. doi: 10.1007/s00702-008-0048-1. Epub 2008 Apr 30. J Neural Transm (Vienna). 2008. PMID: 18446264
AF64A (3 nmol/brain, i.c.v.) produced significant reduction of high-affinity choline uptake (HACU) and high K+-induced ACh release in hippocampal synaptosomes. ...In hippocampal slices superfused with choline-containing artificial cerebro-spinal fluid (ACSF), high K
AF64A (3 nmol/brain, i.c.v.) produced significant reduction of high-affinity choline uptake (HACU) and high K+-induced ACh release in …
MKC-231, a choline uptake enhancer: (3) Mode of action of MKC-231 in the enhancement of high-affinity choline uptake.
Takashina K, Bessho T, Mori R, Kawai K, Eguchi J, Saito K. Takashina K, et al. J Neural Transm (Vienna). 2008 Jul;115(7):1037-46. doi: 10.1007/s00702-008-0049-0. Epub 2008 May 7. J Neural Transm (Vienna). 2008. PMID: 18461273
MKC-231, a choline-uptake enhancer: (1) long-lasting cognitive improvement after repeated administration in AF64A-treated rats.
Bessho T, Takashina K, Eguchi J, Komatsu T, Saito K. Bessho T, et al. J Neural Transm (Vienna). 2008 Jul;115(7):1019-25. doi: 10.1007/s00702-008-0053-4. Epub 2008 May 7. J Neural Transm (Vienna). 2008. PMID: 18461272
Effect of the novel high affinity choline uptake enhancer 2-(2-oxopyrrolidin-1-yl)-N-(2,3-dimethyl-5,6,7,8-tetrahydrofuro[2,3-b] quinolin-4-yl)acetoamide on deficits of water maze learning in rats.
Bessho T, Takashina K, Tabata R, Ohshima C, Chaki H, Yamabe H, Egawa M, Tobe A, Saito K. Bessho T, et al. Arzneimittelforschung. 1996 Apr;46(4):369-73. Arzneimittelforschung. 1996. PMID: 8740080
Anti-aging effect of DX-9386 in senescence accelerated mouse.
Zhang Y, Takashina K, Saito H, Nishiyama N. Zhang Y, et al. Biol Pharm Bull. 1994 Jun;17(6):866-8. doi: 10.1248/bpb.17.866. Biol Pharm Bull. 1994. PMID: 7951158
Preferential impairment of avoidance performances in amygdala-lesioned mice.
Takashina K, Saito H, Nishiyama N. Takashina K, et al. Jpn J Pharmacol. 1995 Feb;67(2):107-15. doi: 10.1254/jjp.67.107. Jpn J Pharmacol. 1995. PMID: 7616685
Characterization of putrescine production in nongrowing Vibrio parahaemolyticus cells in response to external osmolality.
Yamamoto S, Yamasaki K, Takashina K, Katsu T, Shinoda S. Yamamoto S, et al. Microbiol Immunol. 1989;33(1):11-21. doi: 10.1111/j.1348-0421.1989.tb01493.x. Microbiol Immunol. 1989. PMID: 2543889
The cation efflux from cells, measured as the K+ release, was observed whenever the increase in Put production occurred. Furthermore, in vitro experiments showed that NaCl and KCl inhibited ADC to a similar extent, about 70% inhibition being observed at 200 mM. ...These re …
The cation efflux from cells, measured as the K+ release, was observed whenever the increase in Put production occurred. Furthermore, …
MicroRNA expression profiles of neuron-derived extracellular vesicles in plasma from patients with amyotrophic lateral sclerosis.
Katsu M, Hama Y, Utsumi J, Takashina K, Yasumatsu H, Mori F, Wakabayashi K, Shoji M, Sasaki H. Katsu M, et al. Among authors: takashina k. Neurosci Lett. 2019 Aug 24;708:134176. doi: 10.1016/j.neulet.2019.03.048. Epub 2019 Jun 4. Neurosci Lett. 2019. PMID: 31173847
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