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Targeted disruption of the MyD88 gene results in loss of IL-1- and IL-18-mediated function.
Adachi O, Kawai T, Takeda K, Matsumoto M, Tsutsui H, Sakagami M, Nakanishi K, Akira S. Adachi O, et al. Immunity. 1998 Jul;9(1):143-50. doi: 10.1016/s1074-7613(00)80596-8. Immunity. 1998. PMID: 9697844
Essential role of nuclear factor (NF)-kappaB-inducing kinase and inhibitor of kappaB (IkappaB) kinase alpha in NF-kappaB activation through lymphotoxin beta receptor, but not through tumor necrosis factor receptor I.
Matsushima A, Kaisho T, Rennert PD, Nakano H, Kurosawa K, Uchida D, Takeda K, Akira S, Matsumoto M. Matsushima A, et al. J Exp Med. 2001 Mar 5;193(5):631-6. doi: 10.1084/jem.193.5.631. J Exp Med. 2001. PMID: 11238593 Free PMC article.
Induction of Smad6 mRNA by bone morphogenetic proteins.
Takase M, Imamura T, Sampath TK, Takeda K, Ichijo H, Miyazono K, Kawabata M. Takase M, et al. Biochem Biophys Res Commun. 1998 Mar 6;244(1):26-9. doi: 10.1006/bbrc.1998.8200. Biochem Biophys Res Commun. 1998. PMID: 9514869
Roles of bone morphogenetic protein type I receptors and Smad proteins in osteoblast and chondroblast differentiation.
Fujii M, Takeda K, Imamura T, Aoki H, Sampath TK, Enomoto S, Kawabata M, Kato M, Ichijo H, Miyazono K. Fujii M, et al. Mol Biol Cell. 1999 Nov;10(11):3801-13. doi: 10.1091/mbc.10.11.3801. Mol Biol Cell. 1999. PMID: 10564272 Free PMC article.
ASK1 is essential for JNK/SAPK activation by TRAF2.
Nishitoh H, Saitoh M, Mochida Y, Takeda K, Nakano H, Rothe M, Miyazono K, Ichijo H. Nishitoh H, et al. Mol Cell. 1998 Sep;2(3):389-95. doi: 10.1016/s1097-2765(00)80283-x. Mol Cell. 1998. PMID: 9774977
Mammalian thioredoxin is a direct inhibitor of apoptosis signal-regulating kinase (ASK) 1.
Saitoh M, Nishitoh H, Fujii M, Takeda K, Tobiume K, Sawada Y, Kawabata M, Miyazono K, Ichijo H. Saitoh M, et al. EMBO J. 1998 May 1;17(9):2596-606. doi: 10.1093/emboj/17.9.2596. EMBO J. 1998. PMID: 9564042 Free PMC article.
Modulation of responses to TGF-beta by 1, 25 dihydroxyvitamin D3 in MG-63 osteoblastic cells: possible involvement of regulation of TGF-beta type II receptor.
Iimura T, Oida S, Ichijo H, Goseki M, Maruoka Y, Takeda K, Sasaki S. Iimura T, et al. Biochem Biophys Res Commun. 1994 Oct 28;204(2):918-23. doi: 10.1006/bbrc.1994.2547. Biochem Biophys Res Commun. 1994. PMID: 7980561
Plasmodium berghei infection in mice induces liver injury by an IL-12- and toll-like receptor/myeloid differentiation factor 88-dependent mechanism.
Adachi K, Tsutsui H, Kashiwamura S, Seki E, Nakano H, Takeuchi O, Takeda K, Okumura K, Van Kaer L, Okamura H, Akira S, Nakanishi K. Adachi K, et al. J Immunol. 2001 Nov 15;167(10):5928-34. doi: 10.4049/jimmunol.167.10.5928. J Immunol. 2001. PMID: 11698470
Potentiality of interleukin-18 as a useful reagent for treatment and prevention of Leishmania major infection.
Ohkusu K, Yoshimoto T, Takeda K, Ogura T, Kashiwamura S, Iwakura Y, Akira S, Okamura H, Nakanishi K. Ohkusu K, et al. Infect Immun. 2000 May;68(5):2449-56. doi: 10.1128/iai.68.5.2449-2456.2000. Infect Immun. 2000. PMID: 10768930 Free PMC article.
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