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Intranasal inoculation of a recombinant influenza virus containing exogenous nucleotides in the NS segment induces mucosal immune response against the exogenous gene product in mice.
Takasuka N, Enami M, Itamura S, Takemori T. Takasuka N, et al. Vaccine. 2002 Feb 22;20(11-12):1579-85. doi: 10.1016/s0264-410x(01)00491-1. Vaccine. 2002. PMID: 11858865
NS2Acat induced delayed-type hypersensitivity (DTH) and sensitized the CAT-specific T lymphocytes in the regional lymph nodes, which proliferated and synthesized several cytokines in vitro upon antigenic challenge. ...
NS2Acat induced delayed-type hypersensitivity (DTH) and sensitized the CAT-specific T lymphocytes in the regional lymph nodes, which …
Protective neutralizing influenza antibody response in the absence of T follicular helper cells.
Miyauchi K, Sugimoto-Ishige A, Harada Y, Adachi Y, Usami Y, Kaji T, Inoue K, Hasegawa H, Watanabe T, Hijikata A, Fukuyama S, Maemura T, Okada-Hatakeyama M, Ohara O, Kawaoka Y, Takahashi Y, Takemori T, Kubo M. Miyauchi K, et al. Nat Immunol. 2016 Dec;17(12):1447-1458. doi: 10.1038/ni.3563. Epub 2016 Oct 31. Nat Immunol. 2016. PMID: 27798619
Virus infection induces the development of T follicular helper (T(FH)) and T helper 1 (T(H)1) cells. Although T(FH) cells are important in anti-viral humoral immunity, the contribution of T(H)1 cells to a protective antibody response rema …
Virus infection induces the development of T follicular helper (T(FH)) and T helper 1 (T(H)1) cells. Although …
Formalin-treated UV-inactivated SARS coronavirus vaccine retains its immunogenicity and promotes Th2-type immune responses.
Tsunetsugu-Yokota Y, Ato M, Takahashi Y, Hashimoto S, Kaji T, Kuraoka M, Yamamoto K, Mitsuki YY, Yamamoto T, Oshima M, Ohnishi K, Takemori T. Tsunetsugu-Yokota Y, et al. Jpn J Infect Dis. 2007 May;60(2-3):106-12. Jpn J Infect Dis. 2007. PMID: 17515642
Severe acute respiratory syndrome (SARS) coronavirus: application of monoclonal antibodies and development of an effective vaccine.
Tsunetsugu-Yokota Y, Ohnishi K, Takemori T. Tsunetsugu-Yokota Y, et al. Rev Med Virol. 2006 Mar-Apr;16(2):117-31. doi: 10.1002/rmv.492. Rev Med Virol. 2006. PMID: 16518829 Free PMC article. Review.
Induction of protective immunity against severe acute respiratory syndrome coronavirus (SARS-CoV) infection using highly attenuated recombinant vaccinia virus DIs.
Ishii K, Hasegawa H, Nagata N, Mizutani T, Morikawa S, Suzuki T, Taguchi F, Tashiro M, Takemori T, Miyamura T, Tsunetsugu-Yokota Y. Ishii K, et al. Virology. 2006 Aug 1;351(2):368-80. doi: 10.1016/j.virol.2006.03.020. Epub 2006 May 6. Virology. 2006. PMID: 16678878 Free PMC article.
These rDIs elicited SARS-CoV-specific serum IgG antibody and T-cell responses in vaccinated mice following intranasal or subcutaneous administration. ...
These rDIs elicited SARS-CoV-specific serum IgG antibody and T-cell responses in vaccinated mice following intranasal or subcutaneous …
Influenza A whole virion vaccine induces a rapid reduction of peripheral blood leukocytes via interferon-α-dependent apoptosis.
Ato M, Takahashi Y, Fujii H, Hashimoto S, Kaji T, Itamura S, Horiuchi Y, Arakawa Y, Tashiro M, Takemori T. Ato M, et al. Vaccine. 2013 Apr 19;31(17):2184-90. doi: 10.1016/j.vaccine.2013.02.016. Epub 2013 Feb 19. Vaccine. 2013. PMID: 23434386
HIV-1 Nef impairs multiple T-cell functions in antigen-specific immune response in mice.
Fujii H, Ato M, Takahashi Y, Otake K, Hashimoto S, Kaji T, Tsunetsugu-Yokota Y, Fujita M, Adachi A, Nakayama T, Taniguchi M, Koyasu S, Takemori T. Fujii H, et al. Int Immunol. 2011 Jul;23(7):433-41. doi: 10.1093/intimm/dxr031. Epub 2011 Jun 3. Int Immunol. 2011. PMID: 21642447
Likewise, the in vivo effects of Nef transgenic mouse models supported T-cell hyperresponse by Nef. However, the interpretation is complicated by Nef expression early in the development of T cells in these animal models. Here, we analyzed the consequence of Nef expr …
Likewise, the in vivo effects of Nef transgenic mouse models supported T-cell hyperresponse by Nef. However, the interpretation is co …
Highly attenuated vaccinia virus DIs as a potential SARS vaccine.
Ishii K, Hasegawa H, Nagata N, Mizutani T, Morikawa S, Tashiro M, Suzuki T, Taguchi F, Takemori T, Miyamura T, Tsunetsugu-Yokota Y. Ishii K, et al. Adv Exp Med Biol. 2006;581:593-6. doi: 10.1007/978-0-387-33012-9_107. Adv Exp Med Biol. 2006. PMID: 17037603 Free PMC article. No abstract available.
Novel role of the Ras cascade in memory B cell response.
Takahashi Y, Inamine A, Hashimoto S, Haraguchi S, Yoshioka E, Kojima N, Abe R, Takemori T. Takahashi Y, et al. Immunity. 2005 Aug;23(2):127-38. doi: 10.1016/j.immuni.2005.06.010. Immunity. 2005. PMID: 16111632
Here, we report that in T cell-dependent response, the role of the Ras cascade is confined to memory B cells and possibly marginal zone B cells. ...
Here, we report that in T cell-dependent response, the role of the Ras cascade is confined to memory B cells and possibly marginal zo …
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