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390 results
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Histogram analysis of pharmacokinetic parameters by bootstrap resampling from one-point sampling data in animal experiments.
Takemoto S, Yamaoka K, Nishikawa M, Takakura Y. Takemoto S, et al. Drug Metab Pharmacokinet. 2006 Dec;21(6):458-64. doi: 10.2133/dmpk.21.458. Drug Metab Pharmacokinet. 2006. PMID: 17220561
Enhanced generation of cytotoxic T lymphocytes by heat shock protein 70 fusion proteins harboring both CD8(+) T cell and CD4(+) T cell epitopes.
Takemoto S, Nishikawa M, Guan X, Ohno Y, Yata T, Takakura Y. Takemoto S, et al. Mol Pharm. 2010 Oct 4;7(5):1715-23. doi: 10.1021/mp1001069. Epub 2010 Sep 3. Mol Pharm. 2010. PMID: 20695521
Development of a novel Hsp70-based DNA vaccine as a multifunctional antigen delivery system.
Yamaoka A, Guan X, Takemoto S, Nishikawa M, Takakura Y. Yamaoka A, et al. Among authors: takemoto s. J Control Release. 2010 Mar 19;142(3):411-5. doi: 10.1016/j.jconrel.2009.11.005. Epub 2009 Nov 11. J Control Release. 2010. PMID: 19913062
Bootstrap method-based estimation of the minimum sample number for obtaining pharmacokinetic parameters in preclinical experiments.
Takemoto S, Yamaoka K, Nishikawa M, Yano Y, Takakura Y. Takemoto S, et al. J Pharm Sci. 2010 Apr;99(4):2176-84. doi: 10.1002/jps.21975. J Pharm Sci. 2010. PMID: 19902519
Induction of tumor-specific immune response by gene transfer of Hsp70-cell-penetrating peptide fusion protein to tumors in mice.
Nishikawa M, Otsuki T, Ota A, Guan X, Takemoto S, Takahashi Y, Takakura Y. Nishikawa M, et al. Among authors: takemoto s. Mol Ther. 2010 Feb;18(2):421-8. doi: 10.1038/mt.2009.203. Epub 2009 Sep 1. Mol Ther. 2010. PMID: 19724264 Free PMC article.
Enhanced generation of cytotoxic T lymphocytes by increased cytosolic delivery of MHC class I epitope fused to mouse heat shock protein 70 via polyhistidine conjugation.
Takemoto S, Nishikawa M, Otsuki T, Yamaoka A, Maeda K, Ota A, Takakura Y. Takemoto S, et al. J Control Release. 2009 Apr 2;135(1):11-8. doi: 10.1016/j.jconrel.2008.11.024. Epub 2008 Dec 3. J Control Release. 2009. PMID: 19100299
Heat shock protein derivatives for delivery of antigens to antigen presenting cells.
Nishikawa M, Takemoto S, Takakura Y. Nishikawa M, et al. Among authors: takemoto s. Int J Pharm. 2008 Apr 16;354(1-2):23-7. doi: 10.1016/j.ijpharm.2007.09.030. Epub 2007 Sep 29. Int J Pharm. 2008. PMID: 17980980 Review.
Hsp-based tumor vaccines: state-of-the-art and future directions.
Takakura Y, Takemoto S, Nishikawa M. Takakura Y, et al. Among authors: takemoto s. Curr Opin Mol Ther. 2007 Aug;9(4):385-91. Curr Opin Mol Ther. 2007. PMID: 17694451 Review.
[Development of heat shock proteins with controlled distribution properties and their application to vaccine delivery].
Nishikawa M, Takemoto S, Takakura Y. Nishikawa M, et al. Among authors: takemoto s. Yakugaku Zasshi. 2007 Feb;127(2):293-300. doi: 10.1248/yakushi.127.293. Yakugaku Zasshi. 2007. PMID: 17268149 Review. Japanese.
Pharmacokinetic and tissue distribution mechanism of mouse recombinant heat shock protein 70 in mice.
Takemoto S, Nishikawa M, Takakura Y. Takemoto S, et al. Pharm Res. 2005 Mar;22(3):419-26. doi: 10.1007/s11095-004-1880-0. Pharm Res. 2005. PMID: 15835748
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