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Some anti-chronic inflammatory compounds are DNA polymerase lambda-specific inhibitors.
Mizushina Y, Hirota M, Murakami C, Ishidoh T, Kamisuki S, Shimazaki N, Takemura M, Perpelescu M, Suzuki M, Yoshida H, Sugawara F, Koiwai O, Sakaguchi K. Mizushina Y, et al. Among authors: takemura m. Biochem Pharmacol. 2003 Nov 15;66(10):1935-44. doi: 10.1016/s0006-2952(03)00551-3. Biochem Pharmacol. 2003. PMID: 14599551
A plant phytotoxin, solanapyrone A, is an inhibitor of DNA polymerase beta and lambda.
Mizushina Y, Kamisuki S, Kasai N, Shimazaki N, Takemura M, Asahara H, Linn S, Yoshida S, Matsukage A, Koiwai O, Sugawara F, Yoshida H, Sakaguchi K. Mizushina Y, et al. Among authors: takemura m. J Biol Chem. 2002 Jan 4;277(1):630-8. doi: 10.1074/jbc.M105144200. Epub 2001 Oct 24. J Biol Chem. 2002. PMID: 11677229 Free article.
Vitamin A-related compounds, all-trans retinal and retinoic acids, selectively inhibit activities of mammalian replicative DNA polymerases.
Murakami C, Takemura M, Sugiyama Y, Kamisuki S, Asahara H, Kawasaki M, Ishidoh T, Linn S, Yoshida S, Sugawara F, Yoshida H, Sakaguchi K, Mizushina Y. Murakami C, et al. Among authors: takemura m. Biochim Biophys Acta. 2002 Feb 20;1574(1):85-92. doi: 10.1016/s0167-4781(01)00348-7. Biochim Biophys Acta. 2002. PMID: 11955616
A sulphoquinovosyl diacylglycerol is a DNA polymerase epsilon inhibitor.
Mizushina Y, Xu X, Asahara H, Takeuchi R, Oshige M, Shimazaki N, Takemura M, Yamaguchi T, Kuroda K, Linn S, Yoshida H, Koiwai O, Saneyoshi M, Sugawara F, Sakaguchi K. Mizushina Y, et al. Among authors: takemura m. Biochem J. 2003 Feb 15;370(Pt 1):299-305. doi: 10.1042/BJ20021737. Biochem J. 2003. PMID: 12435270 Free PMC article.
Petasiphenol: a DNA polymerase lambda inhibitor.
Mizushina Y, Kamisuki S, Kasai N, Ishidoh T, Shimazaki N, Takemura M, Asahara H, Linn S, Yoshida S, Koiwai O, Sugawara F, Yoshida H, Sakaguchi K. Mizushina Y, et al. Among authors: takemura m. Biochemistry. 2002 Dec 10;41(49):14463-71. doi: 10.1021/bi020476q. Biochemistry. 2002. PMID: 12463744
1,003 results