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Vitamin D and diabetes.
Takiishi T, Gysemans C, Bouillon R, Mathieu C. Takiishi T, et al. Endocrinol Metab Clin North Am. 2010 Jun;39(2):419-46, table of contents. doi: 10.1016/j.ecl.2010.02.013. Endocrinol Metab Clin North Am. 2010. PMID: 20511061 Review.
Reversal of Diabetes in NOD Mice by Clinical-Grade Proinsulin and IL-10-Secreting Lactococcus lactis in Combination With Low-Dose Anti-CD3 Depends on the Induction of Foxp3-Positive T Cells.
Takiishi T, Cook DP, Korf H, Sebastiani G, Mancarella F, Cunha JP, Wasserfall C, Casares N, Lasarte JJ, Steidler L, Rottiers P, Dotta F, Gysemans C, Mathieu C. Takiishi T, et al. Diabetes. 2017 Feb;66(2):448-459. doi: 10.2337/db15-1625. Epub 2016 Nov 8. Diabetes. 2017. PMID: 28108611 Free article.
Combining MK626, a novel DPP-4 inhibitor, and low-dose monoclonal CD3 antibody for stable remission of new-onset diabetes in mice.
Ding L, Gysemans CA, Stangé G, Heremans Y, Yuchi Y, Takiishi T, Korf H, Chintinne M, Carr RD, Heimberg H, Pipeleers D, Mathieu C. Ding L, et al. Among authors: takiishi t. PLoS One. 2014 Sep 30;9(9):e107935. doi: 10.1371/journal.pone.0107935. eCollection 2014. PLoS One. 2014. PMID: 25268801 Free PMC article.
Oral delivery of glutamic acid decarboxylase (GAD)-65 and IL10 by Lactococcus lactis reverses diabetes in recent-onset NOD mice.
Robert S, Gysemans C, Takiishi T, Korf H, Spagnuolo I, Sebastiani G, Van Huynegem K, Steidler L, Caluwaerts S, Demetter P, Wasserfall CH, Atkinson MA, Dotta F, Rottiers P, Van Belle TL, Mathieu C. Robert S, et al. Among authors: takiishi t. Diabetes. 2014 Aug;63(8):2876-87. doi: 10.2337/db13-1236. Epub 2014 Mar 27. Diabetes. 2014. PMID: 24677716 Free article.
Dietary supplementation with high doses of regular vitamin D3 safely reduces diabetes incidence in NOD mice when given early and long term.
Takiishi T, Ding L, Baeke F, Spagnuolo I, Sebastiani G, Laureys J, Verstuyf A, Carmeliet G, Dotta F, Van Belle TL, Gysemans CA, Mathieu C. Takiishi T, et al. Diabetes. 2014 Jun;63(6):2026-36. doi: 10.2337/db13-1559. Epub 2014 Feb 18. Diabetes. 2014. PMID: 24550187 Free article.
1,25-Dihydroxyvitamin D3 curtails the inflammatory and T cell stimulatory capacity of macrophages through an IL-10-dependent mechanism.
Korf H, Wenes M, Stijlemans B, Takiishi T, Robert S, Miani M, Eizirik DL, Gysemans C, Mathieu C. Korf H, et al. Among authors: takiishi t. Immunobiology. 2012 Dec;217(12):1292-300. doi: 10.1016/j.imbio.2012.07.018. Epub 2012 Aug 1. Immunobiology. 2012. PMID: 22944250
Vitamin D and diabetes.
Takiishi T, Gysemans C, Bouillon R, Mathieu C. Takiishi T, et al. Rheum Dis Clin North Am. 2012 Feb;38(1):179-206. doi: 10.1016/j.rdc.2012.03.015. Epub 2012 Apr 12. Rheum Dis Clin North Am. 2012. PMID: 22525851
Reversal of autoimmune diabetes by restoration of antigen-specific tolerance using genetically modified Lactococcus lactis in mice.
Takiishi T, Korf H, Van Belle TL, Robert S, Grieco FA, Caluwaerts S, Galleri L, Spagnuolo I, Steidler L, Van Huynegem K, Demetter P, Wasserfall C, Atkinson MA, Dotta F, Rottiers P, Gysemans C, Mathieu C. Takiishi T, et al. J Clin Invest. 2012 May;122(5):1717-25. doi: 10.1172/JCI60530. Epub 2012 Apr 9. J Clin Invest. 2012. PMID: 22484814 Free PMC article.
Vitamin D: modulator of the immune system.
Baeke F, Takiishi T, Korf H, Gysemans C, Mathieu C. Baeke F, et al. Curr Opin Pharmacol. 2010 Aug;10(4):482-96. doi: 10.1016/j.coph.2010.04.001. Epub 2010 Apr 27. Curr Opin Pharmacol. 2010. PMID: 20427238 Review.
Here, we describe 1,25(OH)(2)D(3) as an immunomodulator targeting various immune cells, including monocytes, macrophages, dendritic cells (DCs), as well as T-lymphocytes and B-lymphocytes, hence modulating both innate and adaptive immune responses. ...
Here, we describe 1,25(OH)(2)D(3) as an immunomodulator targeting various immune cells, including monocytes, macrophages, dendritic cells (D …
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