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Antioxidant functions of sulforaphane: a potent inducer of Phase II detoxication enzymes.
Fahey JW, Talalay P. Fahey JW, et al. Among authors: talalay p. Food Chem Toxicol. 1999 Sep-Oct;37(9-10):973-9. doi: 10.1016/s0278-6915(99)00082-4. Food Chem Toxicol. 1999. PMID: 10541453 Review. No abstract available.
Protection of humans by plant glucosinolates: efficiency of conversion of glucosinolates to isothiocyanates by the gastrointestinal microflora.
Fahey JW, Wehage SL, Holtzclaw WD, Kensler TW, Egner PA, Shapiro TA, Talalay P. Fahey JW, et al. Among authors: talalay p. Cancer Prev Res (Phila). 2012 Apr;5(4):603-11. doi: 10.1158/1940-6207.CAPR-11-0538. Epub 2012 Feb 7. Cancer Prev Res (Phila). 2012. PMID: 22318753 Free PMC article.
Relevance of anti-inflammatory and antioxidant activities of exemestane and synergism with sulforaphane for disease prevention.
Liu H, Talalay P. Liu H, et al. Among authors: talalay p. Proc Natl Acad Sci U S A. 2013 Nov 19;110(47):19065-70. doi: 10.1073/pnas.1318247110. Epub 2013 Nov 4. Proc Natl Acad Sci U S A. 2013. PMID: 24191056 Free PMC article.
We show here that exemestane transcriptionally activates NAD(P)H:quinone oxidoreductase 1 (NQO1) and heme oxygenase 1 (HO-1), typical chemoprotective gene products, in a wide variety of mouse, rat, and human cells. ...
We show here that exemestane transcriptionally activates NAD(P)H:quinone oxidoreductase 1 (NQO1) and heme oxygenase 1 (HO-1), typical …
Urease from Helicobacter pylori is inactivated by sulforaphane and other isothiocyanates.
Fahey JW, Stephenson KK, Wade KL, Talalay P. Fahey JW, et al. Among authors: talalay p. Biochem Biophys Res Commun. 2013 May 24;435(1):1-7. doi: 10.1016/j.bbrc.2013.03.126. Epub 2013 Apr 11. Biochem Biophys Res Commun. 2013. PMID: 23583386 Free PMC article.
Neuroprotective effects of sulforaphane after contusive spinal cord injury.
Benedict AL, Mountney A, Hurtado A, Bryan KE, Schnaar RL, Dinkova-Kostova AT, Talalay P. Benedict AL, et al. Among authors: talalay p. J Neurotrauma. 2012 Nov 1;29(16):2576-86. doi: 10.1089/neu.2012.2474. Epub 2012 Sep 20. J Neurotrauma. 2012. PMID: 22853439 Free PMC article.
Sulforaphane (SF), an isothiocyanate derived from broccoli, is a potent naturally-occurring inducer of the Keap1/Nrf2/ARE pathway, leading to upregulation of genes encoding cytoprotective proteins such as NAD(P)H: quinone oxidoreductase 1, and GSH-regulatory enzymes. ...
Sulforaphane (SF), an isothiocyanate derived from broccoli, is a potent naturally-occurring inducer of the Keap1/Nrf2/ARE pathway, leading t …
Inactivation of tautomerase activity of macrophage migration inhibitory factor by sulforaphane: a potential biomarker for anti-inflammatory intervention.
Healy ZR, Liu H, Holtzclaw WD, Talalay P. Healy ZR, et al. Among authors: talalay p. Cancer Epidemiol Biomarkers Prev. 2011 Jul;20(7):1516-23. doi: 10.1158/1055-9965.EPI-11-0279. Epub 2011 May 20. Cancer Epidemiol Biomarkers Prev. 2011. PMID: 21602309 Free PMC article.
Stimulation of phagocytosis by sulforaphane.
Suganuma H, Fahey JW, Bryan KE, Healy ZR, Talalay P. Suganuma H, et al. Among authors: talalay p. Biochem Biophys Res Commun. 2011 Feb 4;405(1):146-51. doi: 10.1016/j.bbrc.2011.01.025. Epub 2011 Jan 8. Biochem Biophys Res Commun. 2011. PMID: 21219867 Free PMC article.
Electrophilic tuning of the chemoprotective natural product sulforaphane.
Ahn YH, Hwang Y, Liu H, Wang XJ, Zhang Y, Stephenson KK, Boronina TN, Cole RN, Dinkova-Kostova AT, Talalay P, Cole PA. Ahn YH, et al. Among authors: talalay p. Proc Natl Acad Sci U S A. 2010 May 25;107(21):9590-5. doi: 10.1073/pnas.1004104107. Epub 2010 May 3. Proc Natl Acad Sci U S A. 2010. PMID: 20439747 Free PMC article.
Direct and indirect antioxidant properties of inducers of cytoprotective proteins.
Dinkova-Kostova AT, Talalay P. Dinkova-Kostova AT, et al. Among authors: talalay p. Mol Nutr Food Res. 2008 Jun;52 Suppl 1:S128-38. doi: 10.1002/mnfr.200700195. Mol Nutr Food Res. 2008. PMID: 18327872 Review.
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