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Two-step mechanism of induction of the gene expression of a prototypic cancer-protective enzyme by diphenols.
Bensasson RV, Zoete V, Dinkova-Kostova AT, Talalay P. Bensasson RV, et al. Among authors: talalay p. Chem Res Toxicol. 2008 Apr;21(4):805-12. doi: 10.1021/tx7002883. Epub 2008 Mar 25. Chem Res Toxicol. 2008. PMID: 18361512
On the mechanisms of induction of cancer-protective enzymes: a unifying proposal.
Prochaska HJ, De Long MJ, Talalay P. Prochaska HJ, et al. Among authors: talalay p. Proc Natl Acad Sci U S A. 1985 Dec;82(23):8232-6. doi: 10.1073/pnas.82.23.8232. Proc Natl Acad Sci U S A. 1985. PMID: 3934671 Free PMC article.
Mercurials and dimercaptans: synergism in the induction of chemoprotective enzymes.
Putzer RR, Zhang Y, Prestera T, Holtzclaw WD, Wade KL, Talalay P. Putzer RR, et al. Among authors: talalay p. Chem Res Toxicol. 1995 Jan-Feb;8(1):103-10. doi: 10.1021/tx00043a014. Chem Res Toxicol. 1995. PMID: 7703353
Chemoprotection against cancer by phase 2 enzyme induction.
Talalay P, Fahey JW, Holtzclaw WD, Prestera T, Zhang Y. Talalay P, et al. Toxicol Lett. 1995 Dec;82-83:173-9. doi: 10.1016/0378-4274(95)03553-2. Toxicol Lett. 1995. PMID: 8597048 Review.
Potency ranking of triterpenoids as inducers of a cytoprotective enzyme and as inhibitors of a cellular inflammatory response via their electron affinity and their electrophilicity index.
Bensasson RV, Zoete V, Berthier G, Talalay P, Dinkova-Kostova AT. Bensasson RV, et al. Among authors: talalay p. Chem Biol Interact. 2010 Jul 30;186(2):118-26. doi: 10.1016/j.cbi.2010.04.026. Epub 2010 Apr 28. Chem Biol Interact. 2010. PMID: 20433811 Free PMC article.
Redox ranking of inducers of a cancer-protective enzyme via the energy of their highest occupied molecular orbital.
Zoete V, Rougée M, Dinkova-Kostova AT, Talalay P, Bensasson RV. Zoete V, et al. Among authors: talalay p. Free Radic Biol Med. 2004 Jun 1;36(11):1418-23. doi: 10.1016/j.freeradbiomed.2004.03.008. Free Radic Biol Med. 2004. PMID: 15135178
Extremely potent triterpenoid inducers of the phase 2 response: correlations of protection against oxidant and inflammatory stress.
Dinkova-Kostova AT, Liby KT, Stephenson KK, Holtzclaw WD, Gao X, Suh N, Williams C, Risingsong R, Honda T, Gribble GW, Sporn MB, Talalay P. Dinkova-Kostova AT, et al. Among authors: talalay p. Proc Natl Acad Sci U S A. 2005 Mar 22;102(12):4584-9. doi: 10.1073/pnas.0500815102. Epub 2005 Mar 14. Proc Natl Acad Sci U S A. 2005. PMID: 15767573 Free PMC article.
Coordinate regulation of enzyme markers for inflammation and for protection against oxidants and electrophiles.
Liu H, Dinkova-Kostova AT, Talalay P. Liu H, et al. Among authors: talalay p. Proc Natl Acad Sci U S A. 2008 Oct 14;105(41):15926-31. doi: 10.1073/pnas.0808346105. Epub 2008 Oct 6. Proc Natl Acad Sci U S A. 2008. PMID: 18838692 Free PMC article.
An exceptionally potent inducer of cytoprotective enzymes: elucidation of the structural features that determine inducer potency and reactivity with Keap1.
Dinkova-Kostova AT, Talalay P, Sharkey J, Zhang Y, Holtzclaw WD, Wang XJ, David E, Schiavoni KH, Finlayson S, Mierke DF, Honda T. Dinkova-Kostova AT, et al. Among authors: talalay p. J Biol Chem. 2010 Oct 29;285(44):33747-55. doi: 10.1074/jbc.M110.163485. Epub 2010 Aug 26. J Biol Chem. 2010. PMID: 20801881 Free PMC article.
Induction of phase 2 genes by sulforaphane protects retinal pigment epithelial cells against photooxidative damage.
Gao X, Talalay P. Gao X, et al. Among authors: talalay p. Proc Natl Acad Sci U S A. 2004 Jul 13;101(28):10446-51. doi: 10.1073/pnas.0403886101. Epub 2004 Jun 30. Proc Natl Acad Sci U S A. 2004. PMID: 15229324 Free PMC article.
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