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The "Prochaska" microtiter plate bioassay for inducers of NQO1.
Fahey JW, Dinkova-Kostova AT, Stephenson KK, Talalay P. Fahey JW, et al. Among authors: talalay p. Methods Enzymol. 2004;382:243-58. doi: 10.1016/S0076-6879(04)82014-7. Methods Enzymol. 2004. PMID: 15047106 Review. No abstract available.
Direct evidence that sulfhydryl groups of Keap1 are the sensors regulating induction of phase 2 enzymes that protect against carcinogens and oxidants.
Dinkova-Kostova AT, Holtzclaw WD, Cole RN, Itoh K, Wakabayashi N, Katoh Y, Yamamoto M, Talalay P. Dinkova-Kostova AT, et al. Among authors: talalay p. Proc Natl Acad Sci U S A. 2002 Sep 3;99(18):11908-13. doi: 10.1073/pnas.172398899. Epub 2002 Aug 22. Proc Natl Acad Sci U S A. 2002. PMID: 12193649 Free PMC article.
246 results